1.Investigation of the Clinic Application of Decompressive Craniotomy
Journal of Kunming Medical University 2006;0(06):-
Most literature consider that the application of decompressive craniotomy with severe brain injury is a great significance,especially in the treatment of refractory in intracranial hypertension after severe traumatic brain injuries to better effect,But its surgical indications and efficacy remains controversial.A review of recent literature at home and abroad,focusing on the surgical indications,surgical methods,timing,effects and complications of decompressive craniectomy for craniocerebral trauma
2.0253-2654(2001)02-0012-04 THE PRELIMINARY RESEARCH ABOUT THE REASONS OF BUSTING BAGS OCCASIONALLY DURING SOY STORAGE
Zhiyuan SUN ; Huanshu LIU ; Xiaobin ZHANG
Microbiology 2001;28(2):12-15
Shan Qi soy has busting bags, bacteria sum overproof, continue acidification and other problems occasionally during the storage. It's probably caused by the Lactobacillus continue growth in the soy. We tried expounding the relationship between growth and producing acid when Lactobacillus growing in the thin fermented material.
3.Methods on application of Chinese medicine to protect ancient books
Xiaobin XU ; Fanhong MENG ; Haishu SUN
International Journal of Traditional Chinese Medicine 2014;36(2):156-158
Objective Pest control is one of the measures in protecting ancient books.To conclude pest control methods of Heilongjiang University of Chinese Medicine Library,a suitable method for promotion can be found.Methods By integrating the practical experience of protecting ancient books in Heilongjiang University,this article discussed concrete applications of Lysimachia foenum-gracum Hance to protect ancient books from infestation.Results The pest control mechanism of Lysimachia foenum-gracum was analyzed.The best pest control effects can be achieved when we identify the origin,choose the right picking season,identify authenticity of the medicine,and correctly use it.Conclusion Using Chinese traditional medicine to keep away insect is an environmental friendly way,which is worthy of generalizing.
4.Experimental study on restenosis after percutaneous coronary intervention: effects of fenofibrate on proliferation and apoptosis of cultured human umbilical vein endothelial cells
Guoju SUN ; Xiumei XIE ; Xiaobin CHEN
Chinese Journal of Interventional Cardiology 1993;0(03):-
Objective To establish the cell model of restenosis in vitro and investigate the effects of fenofibrate on the prevention and treatment of the restenosis.Methods Human umbilical vein endothelial cells(HUVECs) were cultured in vitro.The study was designated to 5 groups:(1) control group,(2) LPC group,(3) low-concentration fenofibrate(10 ?mol/L) group,(4) midium-concentration fenofibrate(50 ?mol/L) group,and(5) high-concentration fenofibrate(100 ?mol/L) group.Proliferation and apoptosis of HUVECs were assessed by MTT assay,flow cytometry(FCM) and fluorescence microscopy respectively.Results Compared with the control group,LPC could inhibit the growth and induce apoptosis of HUVECs as well as decrease NO production in HUVECs.Fenofibrate could increase the proliferation and decrease the apoptosis of HUVECs,and also enhance NO production of HUVECs.Conclusion Fenofibrate could improve proliferation and reduce apoptosis and enhance NO production of HUVECs through lysophosphatidylcholine,which may be an important route for fenofibrate to prevent and treat the restenosis after percutaneous coronary intervention.
5.The experimental study of the healing process in the injured rotator cuff
Xiaobin WANG ; Gongyi HUANG ; Changtai SUN
Chinese Journal of Orthopaedics 2000;0(11):-
Objective To observe the reparative response and expression of basic fibroblast growth factor (bFGF) protein in the rotator cuff subjected to subacromial impingement. Methods Subacromial impingement of the infraspinatus tendon was experimentally created in 50 male SD rats by thickening the undersurface of the acromion with one platelike bony transplantation of the ipsilateral scapular spine. The contralateral shoulders that had undergone a sham operation were used as controls. The rats were sacrificed at 3, 7, 14, 28, and 56 th day, the whole shoulder joint was removed for detecting bFGF protein and the reparative response in the impinged infraspinatus tendon. Computer image analysis system were used to monitor the expression intensity and numbers of positive cells of bFGF protein. The OD scores and the size of area represent the expression intensity and numbers of positive cells respectively. Results All rats with experimental subacromial impingement showed an infraspinatus tear on the bursal side of the tendon. The shoulders in the control group were found intact without any alteration. There was proliferating cells in the fragmented tendons and vascularised connective tissue covering the area of ruptured area, whose source was the subacromial bursa. Few tenocytes and bursal cells expressed bFGF protein in unwounded tendons. In contrast, tendons subjected to impingement exhibited an increased signal for bFGF protein in both resident tenocytes concentrated along the epitenon and infiltrating fibroblasts and inflammatory cells from the subacromial bursa. Conclusion The bFGF protein is upregulated during tendon healing and the subacromial bursa is the main source of both bFGF secreting and rotator cuff repair; one should preserve as much as possible the subacromial bursa.
6.Clinical application of transendoscopic Doppler ultrasonography: a preliminary study
Cong ZHAO ; Xiaobin SUN ; Wei SHI
Chinese Journal of Digestive Endoscopy 2001;0(01):-
Objective To evaluate the clinical application of transendoscopic Doppler ultrasonogra-phy in various gastrointestinal diseases. Methods Transendoscopic Doppler ultrasonography was performed in 59 patients with various gastrointestinal diseases. Results The Doppler signals were detected beneath the peptic ulcer base in 29 of 39 patients (74. 4% ) . For acute ulcer bleeding and non - bleeding, the Doppler - positive rates were 87. 5% and 65. 2% , respectively, and the measured depth of vessels were 0. 49 mm and 0. 65mm (P
7.Research on the layout and construction preparation for 3.0T high-field nuclear magnetic resonance equipment room
Jijiang SUN ; Xiaobin HE ; Yansheng BU
China Medical Equipment 2013;(10):53-54,55
Objective:To do the research on the layout and construction preparation for 3.0T high-field nuclear magnetic resonance equipment room, greatly shorten the construction time and save money for hospital by the safe and convenient usage. Methods: According to the specific characteristics of hospital sitting in full consideration of transportation and distribution, ventilation, bearing, electromagnetic interference and so on, we implement gradually, were ready to work in the construction. Results: Computer room location requirements bearing within 10 tons, magnets, center of 3 m in ferromagnetic material to do assessment, and moving around the car and the transformer must be beyond 3G line, required a special transformer and the capacity of more than 150 kVA. Equipment grounding resistance is less than 2 ohms, shielding room of insulation is greater than 1000 ohms. Super tube is higher than 3.8 m above the ground, there be no air conditioning air inlet. Water-cooled machine well ventilated, northern region need to get the winter outdoor antifreeze. Exhaust air change per hour between magnet design of not less than 12 times. Conclusion: Hospital construction for large equipment and ancillary equipment is installed in the process of each link to match reasonably, pay attention to the collaboration between different units and at the same time. Reasonable equipment layout and construction preparation is the guarantee of equipment installation smoothly.
8.Advance in Transplants for Spinal Cord Injury (review)
Xiaobin CHEN ; Tiansheng SUN ; Zhouyong MA
Chinese Journal of Rehabilitation Theory and Practice 2007;13(11):1005-1007
Several transplantation strategies have made some advance in promoting axonal regeneration and partial functional recovery in animal models of spinal cord injury and in some clinical trials.This article reviews the transplants used in recent laboratory studies and phase 1 clinical trials,introduces their application condition and mechanism of action,etc.
9.Retrospective analysis on simultaneous bilateral total hip arthoplasty in 93 patients
Ruyin HU ; Xiaobin TIAN ; Li SUN ; Bin QIU ; Wei HAN
Chinese Journal of Trauma 2011;27(7):622-626
Objective To retrospectively study the perioperative complications and postoperative function recovery of 93 patients treated with simultaneous bilateral total hip arthroplasty (THA). Methods A total of 93 patients (186 hips) undergone simultaneous bilateral THA from January 1999 to January 2009 in our hospital were involved in this study. There were 70 males and 23 females (at age range of 25-65 years, average 41. 8 years). The preoperative diagnosis included bilateral avascular necrosis of femoral head in 48 patients, rheumatoid arthritis in 11, developmental dysplasia of the hip in 26 and ankylosing spondylitis in 8. The intraoperative blood loss, Harris scores before operation and at final followup as well as perioperative complications were analyzed. Results All the patients were followed up for average 65 months (12-118 months), which showed femur fracture in one patient and infection six months after discharge in one patient. The Harris score was increased from (36.7 ±6.1) points preoperatively to (91.2±6.2) points at the final follow-up. Hip pain disappeared in 92 patients after operation and radiograph showed no loosening. Actebular loosening occurred in one patient 49 months after operation and was revised accordingly. Conclusion Under strict control of operation indications, suitable choice and implantation of the prosthesis and emphasis on perioperative management and postoperative rehabilitation, simultaneous bilateral THA is a safe and effective choice for bilateral hip diseases.
10.The impact of operative timing on clinical outcomes in elderly hip fracture
Xiaowei WANG ; Tiansheng SUN ; Shuqing LIU ; Xiaobin CHEN ; Congcong QIN
Chinese Journal of Orthopaedics 2010;30(12):1171-1174
Objective To study the effect of operative timing on clinical outcomes in elderly hip fracture. Methods Two hundred sixty-seven patients with hip fracture were treated from July 2006 to May 2008. The patients who had an operation within two days (the early surgery group) were compared with the outcome for those who had an operation more than two days (the later surgery group). Outcomes measured were mortality, post-operative complications, operative details, the comorbidity and the activities of daily living of patients. Results One hundred and sixteen patients were included in the study. There were 45 cases in the early surgery group, including 13 males and 32 females. The patients ranged from sixty-five to eightyeight years old, with an average age of 78.76 years. While there were 71 patients in the late surgery group,including 24 males and 47 females. The patients ranged from sixty-six to one hundred and three years old,with an average age of 80.00 years. The demographic data of patients show no significant difference in two groups. There was no difference in intraoperative conditions such as anesthesia, amount of bleeding, type of fixation between two groups. Patients in early surgery group experienced shorter length of hospital stay, and fewer pulmonary complications. The mortality of early surgery group do not show a significant increase at discharge, 6 month, 12 month postoperatively compared to that of the later surgery group. However patients in the early surgery group show a significant increase of ADL scores at discharge, 6 month postoperatively,but not at 12 month. Conclusion The timing of surgery has an impact on clinical outcome in elderly hip fracture. Early surgery was associated with improved function in the first 6 month postoperatively, but not 12months, but it was not associated with mortality.