2.Expression and clinical significance of inhibitor-of-apoptosis Livin in laryngeal squamous carcinoma
Hong XIAO ; Changyou JI ; Jichuan CHEN
Journal of Third Military Medical University 2003;0(11):-
0.05),but had positive relationship with the clinical stages and lymphatic metastasis of the tumor. Conclusion Livin ? is highly expressed in the tissues and peripheral blood cell from the patients of laryngeal squamous carcinoma,which is closely related to the clinical stages and lymphatic metastasis of the tumor.
3.32 sequela patients of ankle fracture treated with modulated medium frequency low frequency current hydroelectric bath
Chinese Journal of Rehabilitation Theory and Practice 2004;10(6):360-361
ObjectiveTo observe effects of modulated medium frequency low frequency current hydroelectric bath therapy on sequela of ankle fracture.Methods32 sequela patients of ankle fracture were treated with ZM-C type intellectual faculties intermediate frequency therapeutics instrument. Modulated medium frequency square all wave,the frequency of carry wave was 4 KHz,and the frequency of modulated wave was 100 Hz. The water temperature was 40℃. 30 minutes was a time,12 times was a course. Before and after treatment,results were contrasted themselves.ResultsAfter treatment,32 patients all got satisfactory effects,the shorter of the course,the better of the effect.ConclusionThe modulated medium frequency low frequency current hydroelectric bath therapy is a simple,safe and better effect method for sequela of ankle fracture.
6.Changes of the Soleus Muscle Mass and Expression of Myosin Heavy Chain Isoforms mRNA after Acute Spinal Cord Transection
Xiao-hua FAN ; Shu-rong JI ; Hong-jun ZHOU
Chinese Journal of Rehabilitation Theory and Practice 2006;12(4):298-300
ObjectiveTo investigate the rule of changes of the soleus mass and expression of myosin heavy chain (MHC) isoforms mRNA.Methods40 female Wistar rats were divided randomly into the control group and three spinal cord transection (ST) groups, ST7, ST15, and ST30 with 10 animals in each group. Rats in ST groups were subjected to a complete ST between T8 and T10 levels. The right soleus was dissected and weighed at 7, 15, 30 days after ST, and the expression of MHC mRNA isoforms was measured by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR).ResultsThe Absolute and relative soleus masses in three ST groups were lower significantly than those of control group (P<0.05). The soleus mass in ST15 and ST30 groups were lower than that of ST7 group (P<0.05). The soleus of control group predominantly expressed MHC-I and some MHC-IIa, whereas the soleus began to express MHC-IIx and MHC-IIb after ST, except for MHC-I and MHC-IIa. ST induced consistently down-regulation of MHC-I mRNA and up-regulation of MHC-IIx and MHC-IIa at three time points after ST. The level of MHC-IIb mRNA expression was very low at three time points after ST.ConclusionST can influence the soleus mass at early stage after ST. ST induces a shift toward a faster muscle phenotype from slow to fast MHC isoform. MHC demonstrates plasticity in response to decrease neuromuscular activation.
7.Early Stage Syphilis: Clinical and Pathological Analysis of 1200 Cases
Xiao-Ping LV ; Hui JI ; Xiao-Zhuang XU ; Si-Ning FANG ; Feng XIONG ; Xiao-Fang HUANG ; Fang-Juan LI ; Xiao-Hong DU ;
Chinese Journal of Nosocomiology 2006;0(02):-
OBJECTIVE To study the clinic feature and cause of misdiagnosis of early stage syphilis and evaluate the significance of histopathology in the diagnosis of the disease. METHODS Totally 1 200 early syphilis cases were analyzed.The serologic test for syphilis was performed.Thirty five of them were performed with histopathological examination. RESULTS The primary syphilis was found to be commonly misdiagnosed as chancroid,genital herpes,scabies nodules and ulcus vulvae acutum.For secondary syphilis,macular syphilide and maculopapular syphilide were easily misdiagnosed as pityriasis rosea or dermatitis.The papulosquamous syphilide was commonly misdiagnosed as psoriasis.The condyloma latum was commonly misdiagnosed as condyloma acuminatum. CONCLUSIONS The serologic test is important in diagnosis of primary syphilis.The histopathologic test plays a role in diagnosis of primary syphilis,condyloma latum and papulosquamous syphilide,but of limited value in diagnosis of macular syphilide.
8.Expression of ProEXC, p16 and Ki-67 in cervical intraepithelial lesion by immunohistochemistry: diagnostic and clinical significance.
Qi-chang YANG ; Hong-bin LIU ; Yan ZHU ; Xiao-juan ZHANG ; Yi SHEN ; Xiao-hua JI
Chinese Journal of Pathology 2012;41(6):405-407
Adult
;
Aged
;
Aged, 80 and over
;
Antibodies, Monoclonal
;
metabolism
;
Antigens, Neoplasm
;
immunology
;
metabolism
;
Biomarkers, Tumor
;
metabolism
;
Carcinoma, Squamous Cell
;
diagnosis
;
metabolism
;
pathology
;
Cell Cycle Proteins
;
immunology
;
metabolism
;
Cervical Intraepithelial Neoplasia
;
diagnosis
;
metabolism
;
pathology
;
Cyclin-Dependent Kinase Inhibitor p16
;
metabolism
;
DNA Topoisomerases, Type II
;
immunology
;
metabolism
;
DNA-Binding Proteins
;
immunology
;
metabolism
;
Female
;
Humans
;
Immunohistochemistry
;
Ki-67 Antigen
;
metabolism
;
Middle Aged
;
Minichromosome Maintenance Complex Component 2
;
Nuclear Proteins
;
immunology
;
metabolism
;
Uterine Cervical Neoplasms
;
diagnosis
;
metabolism
;
pathology
;
Young Adult
9.Study on the relationship between hepatocellular carcinoma and the interaction between polymorphisms in DNA repair gene XPD and environmental factors
Xiao-Yun ZENG ; Xiao-Qiang QIU ; Long JI ; Hong-Ping YU
Chinese Journal of Epidemiology 2009;30(7):702-705
Objective To study the relationship between hepatocellular carcinoma and the interaction of polymorphisms in DNA repair gene XPD with environmental factors. Methods A hospital-based ease-control study on hepatoeellular carcinoma was conducted. All the hepatocellular carcinoma eases (n=300) were newly diagnosed and controls (n=312) were diagnosed with non-tumor cases. XPD genotype (Lys751 Gin and Asp312 Ash) from blood derived DNA was determined using TaqMan MGB Real-time PCR. Unconditional logistic regression was used to estimate the odds ratios (ORs) and 95% confidence intervals (CIs). Results For XPD condon 751 genotypes, there was no significant difference between frequencies of the AC or CC among patients and controls (P>0.05) (referent AA). The frequency of XPD312A allelic gene was higher in eases than that in controls and was associated with an increased risk (adjusted OR = 2.62,95% CI: 1.626-4.222) for hepatocellular carcinoma when compared with GG genotype. Interactions were found between infection of HBsAg and XPD312 (OR=7.348), as well as between smoking and non-wild type gene of XPD751 (0R=4.291) and XPD312 (OR=5.341). Conclusion DNA repair XPD312A allelic gene might increase the risk of Hepatocellular carcinoma. Interactions between HBsAg infection, smoking and XPD were observed in Hepatocellular carcinoma.
10.Evaluation of an immunohistochemcal combination for diagnosis of prostate adenocarcinoma
Xiao-Hua LE ; Xiao-Jun ZHOU ; Min-Hong PAN ; Hang-Bo ZHOU ; Zhen-Feng LU ; Ji-Zhou GOU ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(10):-
0.05).Conclusion The immunohistoehemical combination of P504S,PSA,PAP,p63 and 341?E12 is a good adjuvant method to diagnose prostate adenocarcinoma.