Principles of constructing medical information technology curriculum system were pro-posed revolving round the core problem of how to combine needs of developing life science with culturing talents who can independently apply information technology knowledge in studying and researching. De-tailed implementing measures for constructing medical information technology curriculum system were summarized after repeated practical teaching. Longitudinal classification based on discipline and trans-verse classification based on teaching level were combined to construct the whole standard course. Finally, courses were appropriately distributed according to detailed culturing objectives for students in medical universities and colleges,thus a suitable medical information technology curriculum system in medical universities and colleges was formed.

After the need of medical information professionals was analyzed, the reform of training model for medi-cal information professionals in Department of Information Management and Information System, Hubei Medical and Pharmaceutical College, was described in aspects of the position of its training target, construction of its teaching team, optimization of its course teaching system structure, updating of its teaching methods, and improvement of its practical ability training system in order to provide certain beneficial experiences and reference for the training of medical information professionals in higher education institutions.

Objective To approach the clinical characteristics of extrapulmonary complication induced by mycoplasma pneumoniae(MP) infection and infectious mononucleosis syndrome. Methods The MP-IgM(+), EBV- IgM(+) were determined by enzyme- linked immunosorbent assay.There were 18 cases infected with MP and infectous mononucleosis syndrome with abnormal fever,cervix lyphadenectasis,pharyngitis,liver and spleen intumescence,lung infection, and so on.They were analyzed by reviewing.Results There were 8 cases(44.4%) with extrapulmonary complication, among them 3 cases(16.6%) with liver injury,1 case (5.56%) with heart injury,2 cases(11.1%) with both heart and liver injuries,1 case(5.56%) with urinary system injury (nephritis), 1 case (5.56%) with nervous system injury (encephalitis).The complication usually arised 1 week after primary affection, but had no typical clinical symptoms.There was only 1 case with encephalitis who expressed the symptom of nervous system symptom firstly, and was clinically dia- gnosed by assistant examinations. All the cases recovered after 3 weeks′ treatment with macrolides, 5-7 days with ganciclovir, and also with regular complication and support treatments.Conclusions The incidence of extrapulmonary complication induced by MP infection and infectous mononucleosis syndrome is higher than that by the single infection, and its clinical symptom isn′t obvious and is easy to be covered by original illness. And a few showing the extrapulmonary as the first symptom is easily mistakenly diagnosed .As a result, the prognosis is favorable if we make subsidiary inspection and diagnosis as soon as possible and give it with regular treatment.

The diagnosis of myocardial damage in systemic lupus erythematosus(SLE) is mainly based on clinical symptoms,physical examinations and electrocardiographic abnormality,echocardiographic changes,and myocardial enzymologic diversity in general.In recent years,it has been suggested that cardiac troponin I possesses high sensitivity and specificity in the diagnosis of myocardial damage.Lupus myocardial damage is diagnosed definitively depending on endomyocardial biopsy.Its treatment has been empirical,and hormone combined with immunodepressive is routine treatment.According to pathogenetic condition,there are still several therapies such as intravenous immunoglobulin therapy,blood purification and autologous hematopoietic stem cell transplantation,extracorporeal membrane oxygenation,and so on.Most often,myocardial dysfunction in SLE is of subclinical progression,and that early diagnosis and prompt treatment may play an important role in relieving patients' condition,raising quality of life and improving prognosis.

Reflex sympathetic dystrophy after stroke,also called shoulder-hand syndrome(SHS),is a common complication of stroke.It is presumed that SHS is consequence of many factors,including periphery injury,effect of sympathetic never system,neurogenic inflammation,and plasticity of central nervous system.

Objective To review the contents and effects of behavioral risk factor surveillance system (BRFSS) and analyzed the application of BRFSS,citizens' health condition and its related risk factors in China.Then summarize the related problems in using BRFSS.Methods The literatures about Chinese research of BRFSS were searched from four databases in China,and a qualitative analysis was conducted.Results 18 case control or cohort studies were involved in the final qualitative analysis,the results showed that there was a positive tendency of people' s health related knowledge.However,people' s improvement of health behavior was at a slow speed,and the most popular health related risk factors consisted of smoking,alcohol drinking,lack of physical exercise,unbalanced diets,overweight,etc.Conclusion By using BRFSS,people' s health status and related risk factors could be accessed with flexibility timely and accurately.Thus can make great contributions for accessing,analyzing and tracking health status and health behavior of the population,finding the targeted population and evaluating effectiveness of health intervention,and this will also be helpful for the performance of health promotion programs and formulation of health policy.In addition,new technologies should be added into survey approaches and guarantee of data quality.

Objective To explore the relationship between apolipoprotein E ( ApoE ) genotype and diabetic nephropathy (DN) in Chinese Han population of Guangdong province. Methods 63 cases of DN patients were selected as group A; 57 diabetes patients without complications as group B; 55 healthy persons as group C. ApoE genotype of all objects were measured. Results ApoE2 in the group A was the highest, while the differences in other groups were not obvious. Detection of ApoE3 and ApoE4 was not obvious in three groups. The Level of triglyceride (TG) was highest inε2 group, and the level of total cholesterol (TC) and low density lipoprotein LDL-C were highest in ε4 groups. Conclusions In Chinese Han population of Guangdong province , ApoE gene polymorphism and DN are closely interrelated , and the occurrence ofε2 is proportionate to DN.

Objective To study the method of development of PHT PB resistant amygdala kindled rats. Methods By examining the effects of the antiepileptic drugs PHT and PB in a group of rapidly kindled rats,the 40 animals with different sensitivity to these drugs were selected. Then using immunohistochemistry method to determinate the expression of PGP in the brain of the rats. Results Using determination of the after discharge threshold for evaluation of PHT′s and PB′s anticonvulsant effects, 6 animals showed no increase in their ADT at repeated test trials with PHT or PB (from PHT PB resistant rats), and 6 animals exhibited reproducible increase in ADT about 100% after injection of PHT or PB (from PHT PB nonresistant rats). The immunohisto chemistry for P glycoprotein showed increased staining in capillary endothelium in the samples from PHT PB resistant rats as compared with staining in PHT PB nonresistant rats,in extensive fields of bilateral cerebral hemispheres ( P

Objective To investigate the effect of insulin resistance(IR) on the persons with abnormal blood glucose who underwent dietary interventions.Methods 194 individuals with abnormal blood glucose were selected from hyperlipidemia population taking the community intervention program in districts of Beijing.The insulin resistance and insulin action index(IAI) were calculated with fasting blood glucose(FBG) and fasting blood insulin(FINS),and analyzed the relationship of variety on their blood glucose,serum lipids and body weight,body mass index(BMI),waist circumference,waist hip ratio(WHR).Results 1) Blood glucose(FBG),triglyceride(TG),waist circumference and WHR had significant positive relationship with IR but negative with IAI;2) In the intervention group,FBG and TG were reduced significantly in the subgroup with highest IAI.Conclusions IR was related with blood glucose,serum lipids,waist circumference and WHR,but no significant relation with body weight and BMI;It was possible that IR had some effect on dietary intervention.