Objective:To investigate the effect of enhanced external counterpulsation(EECP)on serum nitric oxide(NO),malondialdehyde(MDA) and superoxide dismutase(SOD) in patients with coronary heart disease(CHD) and its mechanism.Methods:The serum NO,MDA and SOD levels of 54 cases of CHD and 20 normal controls were tested.Patients were divided into EECP group(30cases) and medication group(24 cases).The serum concentrations of NO,MDA and SOD of each group before and after treatment were compared for the correlation analysis.Results:Before treatment,compared with the normal controls,the serum levels in CHD patients were as follows.NO were much lower(P0.05).Correlation analyses showed that in EECP group,there was negative correlation between NO and SOD(r=-0.47,P

Animals ; Brain ; growth & development ; metabolism ; Emotions ; Glucocorticoids ; therapeutic use ; Humans ; Memory ; RNA, Messenger ; analysis ; Receptors, Glucocorticoid ; analysis ; genetics ; physiology

Cardiovascular Diseases ; complications ; prevention & control ; Diabetes Mellitus, Type 2 ; complications ; prevention & control ; Humans ; Metabolic Syndrome ; complications ; prevention & control

Objective To investigate the correlation between NT‐proBNP ,hs‐CRP level ,echocardiography and early avascu‐lar necrosis of coronary artery syndrome (ACS) ,coronary artery lesion degree .Methods 142 patients admitted in this hospital for chest pain from March 2013 to February 2014 were enrolled ,and all patients′history ,electrocardiogram (ECG) ,plasma levels of N‐terminal pro‐Brain Natriuretic Peptide (NT‐proBNP) ,hypersensitive C‐reative protein (hs‐CRP) and cTnT were recorded or tested within 24 hours ,while left ventricular ejection fraction (LVEF) and left ventricular end‐diastolic diameter (LVEDd) were recorded by echocardiography .According to the history and coronary angiography results conducted during hospitalization ,patients were di‐vided into acute ST segment elevation myocardial infarction (STEMI) group ,acute non‐ST segment elevation myocardial infarction (NSTEMI) group ,unstable angina pectoris (UA) group and control group (normal coronary angiography ,cTnT and ECG) .Pa‐tients with abnormal coronary angiography results were further divided into single vessel lesion group ,double vessel lesion group and triple vessel lesion group .The differences of plasma NT‐proBNP level ,hs‐CRP level and LVEF in each group ,and multivariate linear regression analysis were conducted to find out the independent risk factors for elevated plasma NT‐proBNP .Results 102 ACS patients and 40 normal patients were enrolled .Plasma levels of NT‐proBNP ,hs‐CRP and LVEF in NSTEMI group (n=30) and STEMI group (n=32) were significant different from UA group (n=40) and control group (n=40) respectively (P<0 .05) . The NT‐proBNP levels in control group and triple vessel lesion group (n=41) were respectively significant different from both sin‐gle vessel lesion group (n=30) and double vessel lesion group (n=31) (P<0 .05) .Multivariate linear regression analysis showed that ,plasma hs‐CRP level (P=0 .007) ,coronary artery lesion degree (P=0 .00) and history of diabetes (P=0 .006) were positive associated factors of NT‐proBNP level ,while LVEF was the negative associated factors of NT‐proBNP level(P=0 .036) .Conclusion Plasma NT‐proBNP level ,hs‐CRP level and LVEF are closely related to ACS ,and they might play an important role in determi‐ning the extent of early ischemic necrosis and clinical classification .Plasma NT‐proBNP level could be an important molecular mark‐er to reflect the degree of coronary artery lesion .

To evaluate the curative effect and drug tolerance in the treatment of severe bacterial keratitis and conjunctivitis by levofloxacin.
●METHODS: Totally 195 patients with severe bacterial keratitis and conjunctivitis were included in this study. Based on the sequence of enrollment, they were randomly divided into three groups: group A ( 65 patients) received levofloxacin, group B ( 65 patients) received suture method under microscope, group C received suture method with loupe besides the same basic operative treatment in the two groups. The curative effect and drug tolerance were observed and compared statistically.
●RESULTS: ln group A, 54 cases were cured, in the rate of 83. 1%, 7 cases ( 10. 8%) were excellent, 3 cases (4. 6%) were valid, 1 case (1. 5%) was invalid. ln group B, 25 cases (38. 5%) were cured, 6 cases (9. 2%) were excellent, 23 cases (35. 4%) were valid, 11 cases (16. 9%) were invalid. ln group C, 4 cases (6. 2%) were cured, 3 cases (4. 6%) were excellent, 36 cases (55. 4%) were valid, 22 cases (33. 8%) were invalid. The curative effect and drug tolerance among groups had obvious differences (P<0. 05).
●CONCLUSlON: Levofloxaoin is effective and safe for the treatment of bacterial conjunctivitis and keratitis, which is not resistant and worthy of promotion.

?AIM: To explore the application of 25G vitreous cavity perfusion in phacoemulsification for cataract after vitrectomy.?METHODS:Forty-eight patients (50 eyes) with cataract after pars planavitrectomy in our hospital from September 2013 to September 2014 were selected to receive phacoemulsification and implantation of artificial lens with 25G vitreous cavity perfusion. Best corrected visual acuity ( BCVA ) , intraocular pressure ( IOP ) , postoperative discomfort, healing of scleral puncture and postoperative complications were observed.?RESULTS: All patients underwent surgery successfully. Compared to before operation, there was less patients with BCVA ≤0. 1, more patients with BCVA 0. 3-0. 5,>0. 5,>0. 3 (P<0. 05). The visual acuity of 1 eye decreased because of vitreous hemorrhage caused by original fundus lesion recurrence. The mean IOP before operation and at 1, 7d, 6mo after operation were 14. 67±0. 62mmHg, 14.75±0.56mmHg, 14.86±0.58mmHg, 14.88±0.59mmHg, respectively. There were no statistically significant differences of IOP between that before operation and those at 1, 7d, 6mo after operation (P>0. 05). No obvious eye discomfort and severe complications after operation were observed.? CONCLUSION: The effect of 25G vitreous cavity perfusion in phacoemulsification for cataract after vitrectomy is good and it can maintain IOP, keep anterior chamber stable and decrease the complications risk.

Objective To study Evaluation of serum soluble ST2 protein and brain natriuretic peptide(NT-proBNP)in patients with acute heart failure and prognosis of patients with acute heart failure.Methods Fifty cases patients with acute heart failure from April 2014 to April 2015 in the First Hospital of Traditional Chinese and Western Medicine of Beijing were researched.Detection of all patients with serum ST2,NT-proBNP,50 patients with acute heart failure were divided into heart failure group,50 healthy persons were selected as the control group.The control group and the observation group general heart failure data,the observation group and the control group of cardiac biomarker blood level,cardiac function level NT-proBNP blood concentration level,classification of cardiac function between ST2 blood concentration level were compared.Results Cr,BUN of heart failure group were higher than the control group,there was no significant difference between other indicators(P＞0.05).ST2((0.46±0.07)ng/L)in heart failure group was lower than the control group((0.66±0.20)ng/L),NT-proBNP((4160.20±57.49)ng/L)was higher than the control group((58.97±4.39)ng/L),heart function IV NT-proBNP blood concentration of the highest(9 428.29±75.93)ng/L,followed by grade III(1 921.01±30.27)ng/L,the second lowest(321.02±16.80)ng/L,(P＜0.01).Heart function IV level ST2 blood concentration was the highest(1.95±0.69)ng/L,followed by grade III(1.27±0.61)ng/L,class II minimum(0.78±0.24)ng/L(P＜0.01).Conclusion The serum ST2 and NT-proBNP are used to detect the patients with acute heart failure,can provide accurate diagnosis basis,has a very important value judgment on the classification and prognosis.

Character Repertoires are supported by DICOM to encode Characters in different languages, in which UTF-8 and GB18030 are for Chinese characters. Each of them can replace Acquiesced Character Repertoire in Attribute Specific Character Set so that Chinese characters can be encoded in data elements. Utility programs compatible with DICOM are also required to support UTF-8 or GB 18030 for unerring representation and encoding.

Objective To examine the expression of macrophage migration inhibitory factor(MIF)in lung tissues of rats with experimental pulmonary fibrosis and to discuss its effects on pulmonary fibrosis.Methods36 male SD rats were randomly divided into two groups:the pulmonary fibrosis group and the control group.Rat pulmonary fibrosis was induced by an intratracheal injection of bleomycin.The following tests were undedaken: HE and Masson staining of lung section,immunohistochemical staining of protein of MIF in the lung,RT-PCR of MIFmRNA in the lung.ResultsCompared with the control group,the mRNA and protein expression of lung MIF on day 7 to 28 in pulmonary fibrosis increased and reached the peak on day 14 after an intratracheal injection of bleomycin(P

The method of reinforcement and elimination are frequently used in TCM therapy on malignant tumor,as mediation method is seldom used.But Dr.CHEN Yi realizes that spirit being invalid is the key to the invasion of malignant tumor,and depression is the key to the pathogenesis of tumor,qi stagnation and blood stasis is its main characteristic.Under the guidance of the spirit-regulating and depression-relieving,on the base of mediation therapy,Dr.CHEN Yi uses Xiaoyao Powder,combined with the therapies of activating blood,dispelling dampness,resolving phlegm,purging the pathogenic fire,promoting digestion,in treating malignant tumor to dredge meridians,make qi and blood unobstructed,eliminate the stagnation,and it has gotten satisfactory results which include improving the patients’life quality,constraining tumor’s development,prolonging patients’ survival time.This text is a brief instruction to the application principle and theoretic basis of CHEN Yi’s law of regulating spirit and relieving depression in malignant tumor therapy.