1.The association of single nucleotide polymorphisms in 5'-regulatory region of ?_2-adrenoceptor gene with hypertension in the elderly
Hong WU ; Junhua XIAO ; Gangming CAI
Chinese Journal of Geriatrics 2001;0(01):-
0 05). The frequency of genotype AA (26 67 %) of the SNPs at position -1 023 bp in severe hypertension group was significantly different from that in normal group(6 98 %, P
2.Obstructive sleep-disordered breathing in infants.
Xiao-hong CAI ; Liang-xing WANG
Chinese Journal of Pediatrics 2013;51(10):753-755
Continuous Positive Airway Pressure
;
Facial Bones
;
abnormalities
;
Humans
;
Infant
;
Larynx
;
pathology
;
Oxygen Inhalation Therapy
;
Pharynx
;
pathology
;
Polysomnography
;
Respiration
;
Risk Factors
;
Sleep Apnea Syndromes
;
diagnosis
;
etiology
;
therapy
;
Sleep Apnea, Obstructive
;
diagnosis
;
etiology
;
therapy
3.The lateral epicondylitisnamed rationality:a systematic review
Ke XIONG ; Wei FAN ; Hong AN ; Xiao CAI ; Tingyi HU
Chinese Journal of Medical Education Research 2015;(1):78-83
Objective By analysis oflateralepicondylitis patients MRI features to explore the lateralepicondylitis namedrationality and authorized its opinions for the ninth edition surgery textbook. Methods Cochrane's systematic review methods were used to retrieve the literature about lateralepi-condylitis patients MRI features fromCochrane Library, Medline, OVID, EMBASE, Chinese biomedical literature database (CBM), VIP, CNKI, Wan fang digital journals, and totally 31 articles were reviewed. 13 articles met the inclusion criteria for the lateral epicondyle of humerus elbow in patients with MRI findings. In accordance with the case-control data RevMan 5.0 software was used for Meta analysis withodds ratio (OR) as count data statistics. Interval estimation wasmade of 95% confidence interval (CI). When the datacannot be performed Meta analysis, only qualitative analysis was made. Results 13 studies met the inclusion criteria, including 315 ipsilateralelbows (5 patients with bilateral disease, 305 patients with unilateral disease) and 169 asymptomatic side of the elbow (98 cases of patients with the contralateral elbow, 71 cases of healthy volunteers). The results of Meta analysis suggested that pa-tients and healthy volunteers of elbow MRI showed statistically significance [OR=88.55, 95%CI=(29.20, 268.57)]. Between ipsilateral elbow and contra lateral of elbow MRI showed statistically significance [OR=80.17, 95%CI=(21.53, 298.59)]. MRI analysis showed that in addition to signs of extensor tendon injury, the elbow was also widely associated with other changes, such as radial collateral ligament in-jury, bone marrow edema, joint effusion, tendon tear, and elbows muscle edema. Conclusion Through MRI findings,the maln pathological changes of the so-called lateralepicondyliti-saremalnly for total ex-tensor tendon and adjacent tissue of chronic injury, Naming the current external humeral epicondylitis is unreasonable. Therefore, periarthritis of lateral epicondyle of humerus seems to be the best appropri-ate term to be usedwhenthe ninth edition surgery textbooksisauthorized.
4.A study on apoptosis of lymphocytes and expression of apoptotic protein in patiens with idiopathic thrombocytopenic purpura
Fang LIU ; Hong XIAO ; Qiong MENG ; Kangrong CAI
Chinese Journal of Immunology 1985;0(03):-
Objective:To investigate the relations between the changes of apoptotic lymphocytes and expression of apoptotic protein and idiopathic thrombocytopenic purpura(ITP).Methods:Flow cytometry was used to detect the percentages of the apoptotic lymphocytes and the expression of Fas,FasL on peripheral lymphocytes,and the serum levels of sFas、sFasL were also determined by a sandwich enzyme-linked immunosorbent assay(ELISA),in 25 patients with ITP.Results:The percentages of the apoptotic lymphocytes(3.35?1.43) and the expression of Fas(32.17?6.54) and FasL(41.14?6.76)were all increased significantly in treated patients whose platelets recovered to normal( P
9.Effect of down-regulation of nucleolin on adriamycin-induced apoptosis and inhibition of proliferation in breast cancer cells.
Xiao-cai TIAN ; Xian-ling LIU ; Chun-hong HU
Chinese Journal of Oncology 2010;32(4):271-272
Antibiotics, Antineoplastic
;
pharmacology
;
Apoptosis
;
drug effects
;
Breast Neoplasms
;
metabolism
;
pathology
;
Cell Line, Tumor
;
Cell Proliferation
;
drug effects
;
Down-Regulation
;
Doxorubicin
;
pharmacology
;
Female
;
Humans
;
Oligonucleotides, Antisense
;
pharmacology
;
Phosphoproteins
;
metabolism
;
RNA-Binding Proteins
;
metabolism
;
Random Allocation
10.Discuss The Strategy of the Development of Scientific Research Secretary in Clinical Department
Xiao CAI ; Ning NING ; Hong ZHI ; Hao GUO
Chinese Journal of Medical Science Research Management 2016;29(3):216-217,221
Scientific research management has become a crucial work in each hospital.The quality of scientific research management directly affects the level of scientific research development.Scientific research secretaries act as the direct participants and grassroots community of scientific research management,whose strengths and weaknesses of development related to the level of scientific research management directly.This study put forward several countermeasures on the barriers of hospital scientific research secretaries development,aiming to promote the development of hospital's scientific research and discipline construction.