1.The relation between local temperature rise and therapeutic effects of focused ultrasound on chronic cervicitis
Journal of Chongqing Medical University 1986;0(03):-
Objective:To explore the relation between therapeutic effects of focused ultrasound(FU)on chronic cervicitis and local temperature rise.Methods:132 cases of chronic cervicitis were treated by FU and local temperature rise was measured. 120 patients were followed up regularly for the following 3 months to observe therapeutic effects and adverse effects.Results: The overall effective rate of FU in treatment of chronic cervicitis unitarily was 97.5%.When the temperature of targeted tissue immediately after FU exposure was between 40℃and 43℃,the therapeutic effects tended to he satisfactory(98.33%)with little adverse effects.Conclusion:A satisfactory therapeutic efficacy could be achieved with single session FU in treatment of chronic cervicitis.And local temperature rise measurement,as a quantification method,is helpful to improve the therapeutic effects.
2.Medical Students' Self-education of Divergent Thinking
Chinese Journal of Medical Education Research 2005;0(05):-
Raising students'divergent thinking should be combined with the whole college education.But for the medical students,it is more vital to realize the importance of divergent thinking,make full use of education resources in university,consciously urge themselves to break through the limits of routines,develop their divergent thinking and make various measures to reinforce the self-education of divergent thinking.
3.Quinolones-induced Allergic Shock: Literature Review of 165 Cases
China Pharmacy 1991;0(05):-
OBJECTIVE:To discuss the general pattern and the characteristics of quinolones-induced allergic shocks.ME_THODS:A total of 165 quinolones-induced allergic shock cases reported in the domestic periodicals in recent 10 years were statistically classified and analyzed.RESULTS:Ten kinds of quinolones involved allergy shocks with ciprofloxacin,ofloxacin and norfloxacin respectively dominated the first 3 places,which account for 69.70% of the total.The incidence of allergy shocks was the highest when used intravenously(64.85%),in particular within the first 30min(70.30%) with the mortality at 2.42%.CO_NCLUSION:Attention should be paid to severe adverse drug reactions in the clinic so as to ensure safe drug use.
4.Gitelman syndrome caused by SLC12A3 gene mutations: a report of pedigree analysis
Journal of Clinical Pediatrics 2017;35(1):33-36
Objective To explore the gene diagnosis of Gitelman syndrome.Methods The clinical data of a child with Gitelman syndrome were retrospectively analyzed along with gene detection results of his elder sister and parents.Results A 6-year-old boy was hospitalized for fever and hypokalemia.Gene detection of SLC12A found a new locus mutation of EXON21 c.2522A>G p.(Asp841Gly) and a heterozygosis of EXON16 c.1946C>T p.(Thr649Met).The diagnosis of Gitelman syndrome was confirmed.His mother carried a heterozygosis mutation of EXON21 c.2522A>G p.(Asp841Gly),while his father and elder sister carried a heterozygosis mutation of EXON16 c.1946C>T p.(Thr649Met).Conclusion Gene detection of SLC12A is helpful in the diagnosis of Gitelman syndrome.The newly discovered mutation of SLC12A3 gene has enriched the mutation spectrum of Gitelman syndrome.
5.Progress in the study of risk factors of age-related macular degeneration
International Eye Science 2014;(6):1054-1057
Age-related macular degeneration ( AMD ) is one of a leading worldwide cause of blindness. AMD is a multifactorial disease, and major risk factors include increasing age, current smoking, previous cataract surgery, environmental factors, nutritional factors, genetic markers through genetic regulate complement, lipid, angiogenesis and extracellular matrix. In addition to treatment, epidemiology, risk factors and genetics research of AMD have been significantly progressed. This article will review risk factors of AMD.
6.The effect of floating-needle therapy combined with rehabilitation training for the hand function recovery of post-stroke patients.
Chinese Acupuncture & Moxibustion 2015;35(8):758-762
OBJECTIVETo explore the improvement of hand motion function,spasm and self-care ability of daily life for stroke patients treated with floating-needle combined with rehabilitation training.
METHODSEighty hand spasm patients of post-stroke within one year after stroke were randomly divided into an observation group and a control group, 40 cases in each one. In the two groups, rehabilitation was adopted for eight weeks,once a day,40 min one time. In the observation group, based on the above treatment and according to muscle fascia trigger point, 2~3 points in both the internal and external sides of forearm were treated with floating-needle. The positive or passive flexion and extension of wrist and knuckle till the relief of spasm hand was combined. The floating-needle therapy was given for eight weeks, on the first three days once a day and later once every other day. Modified Ashworth Scale(MAS), activity of daily life(ADL, Barthel index) scores and Fugl-Meyer(FMA) scores were used to assess the spasm hand degree,activity of daily life and hand motion function before and after 7-day, 14-day and 8-week treatment.
RESULTSAfter 7-day, 14-day and 8-week treatment, MAS scores were apparently lower than those before treatment in the two groups(all P<0. 05), and Barthel scores and FMA scores were obviously higher than those before-treatment(all P<0. 05). After 14-day and 8-week treatment, FMA scores in the observation group were markedly higher than those in the control group(both P<0. 05).
CONCLUSIONFloating-needle therapy combined with rehabilitation training and simple rehabilitation training could both improve hand spasm degree, hand function and activity of daily life of post-stroke patients, but floating-needle therapy combined with rehabilitation training is superior to simple rehabilitation training for the improvement of hand function.
Acupuncture Therapy ; instrumentation ; methods ; Adult ; Aged ; Combined Modality Therapy ; Female ; Hand ; physiopathology ; Humans ; Male ; Middle Aged ; Needles ; Range of Motion, Articular ; Recovery of Function ; Stroke ; therapy ; Stroke Rehabilitation ; Treatment Outcome
7.Practice and reflection on training geriatric postgraduates of clinical medicine
Chinese Journal of Medical Education Research 2012;11(2):132-134
In our university,the training for geriatric postgraduates of clinical medicine is now in the initial stage.Therefore,it is important to explore the training model to improve the quality of postgraduate.The program focused on cultivating geriatric postgraduates' ability of diagnosis and treatment,helping them have the concept of integral service and enhancing their teaching and thinking ability of clinical sciences to provide high-level comprehensive geriatric doctors for the society.
8.Analysis of clinical and pathological characteristics on henoch-schonlein purpura nephritis
Journal of Applied Clinical Pediatrics 2004;0(09):-
Objective To analyze the clinical and pathological characteristics and laboratory outcomes in henoch-schonlein purpura nephritis(HSPN) patients.Methods Twenty patients with HSPN were respectively studied. The clinical characteristics and laboratory outcomes were compared between patients with different glomerulus and renal tubule pathologic classification respectively. Results Patients with grade Ⅲ had a higher proteinuria rate than those with grade Ⅱ,and the glomerulus and renal tubule pathologic markedly changed in grade Ⅲ than that in grade Ⅱ.The HSPN patients had a higher concentration of IgA,C 3 in plasma and of minimal protein in urine than that in normal groups.Conclusions There are both glomerulus and renal tubule pathologic changes in HSPN patients. The basic pathologic changes are parallel and correlated with clinical manifestation.
9.Gut microbiota and nonalcoholic fatty liver disease
Journal of Clinical Hepatology 2017;33(4):774-779
Nonalcoholic fatty liver disease (NAFLD) is a common liver disease with multiple factors involved,and its incidence is gradually increasing around the world.Recent studies have found that gut microbiota is involved in the development and progression of NAFLD.This article summarizes the association between gut microbiota and NAFLD from the aspects of influencing factors for gut microbiota and the roles of gut microbiota and its metabolites in the development and progression of NAFLD and points out that the intervention of gut microbiota and its metabolites may be a new target for the prevention and treatment of NAFLD.
10.Inhibition of curcumin on proliferation of human osteosarcoma U-2OS cells
Journal of Xi'an Jiaotong University(Medical Sciences) 2004;0(05):-
Objective To observe the inhibition of different concentrations of curcumin on cell growth,and explore the molecular mechanism of curcumin on human osteosarcoma.Methods Curcumin of different concentrations(0,10,20 and 40?mol/L) was administered to U-2OS cells of human osteosarcoma for 12h,24h and 48h,respectively.The proliferation of U-2OS cells was measured by MTT assay.Results Curcumin significantly inhibited the proliferation of PC-3 cells in vitro in concentration-and time-dependent manners.The higher the concentration of curcumin,the stronger the inhibition was(10?mol/L,20?mol/L,40?mol/L of r=-0.9638,-0.9778 and-0.9764,respectively,P