Objective: To explore the differences between the internal social adaptation and external social behaviors of freshmen. Methods: Make a survey of 198 freshmen on the internal adaptation and external by General Well-Being Schedule and Undergraduate Social Adaptation Questionnaires. Results:Freshmen' social adaptation mainly involves three factors: interpersonal communication, the state of campus life and performance of studies. The Cronbach alpha of 3 factors were 0.82, 0.87 and 0.90,and the re-test reliability was r=0.73 (P

Basic research in interventional radiology,including transcatheter artery perfusion especially,is progressing slowly due to lack of proper method.Microdialysis technique,a kind of accurate sampling technique in vivo,may help to solve the problem.Just as its name implies,microdialysis means tiny dialysis with advantages of authenticity,exactness and less error.Furthermore it has been applied widely and should be received with great attention and popularity.

The articles concerning intensive effect and progress of interventional therapy for hepatocellular carcinoma (HCC) recurrence were comprehensively reviewed. Along with unceasing abundance of all interventional methods (including transcatheter arterial chemoemblization (TACE),percutaneous dehydrated ethanol injection,radio frequency ablation,percutaneous microwave therapy,argon-helium cryoablation,high-intensity focused ultrasound and radionuclide interventional therapy,etc),combined interven-tional therapies mainly TACE were increasingly appreciated in postoperative HCC recurrence,but still have to be further standardized. With further emerging and maturing of new technologies,such as antiangiogenesis,gene therapy and targeted therapy on HCC metastatic and recurrence specific cycle; the effect of combined therapy will be further promoted. Interventional therapy will play an important role in the prevention and treatment of postoperative HCC recurrence in the foreseen furture.

Objective:To study the cognitive features of text anxiety. Methods: The cognitive features of text anxiety were explored by exploratory factor analysis and confirmatory factor analysis on the basis of interview,questionnaire surveying and criterion.Results:There were 6 cognitive factors leading to test anxiety: self-test, worrying, magnifying conclusion, resistance, preparing, self-efficacy.Conclusion: The 6 factors of cognition about text are related to text anxiety

Objective To explore the antagonistic effect of Schistosoma japonicum soluble adult worm antigen (SWA)and solu-ble egg antigen (SEA)in the mice with type 1 diabetes.Methods The 24 successful modeling type 1 diabetes mice were randomly divided into three groups (A,B,C group,n=8).SWA and SEA of Schistosoma japonicum were prepared.Mice in A group were immunized by abdominal subcutaneous multi-point injection SWA.Mice in B group were immunized by abdominal subcutaneous multi-point injection SEA.And mice models of C group were immunized by PBS instead of antigen through abdominal subcutaneous injection.The mice got immunization once a week,a total of four times.4 weeks later,the mice were sacrificed,and serum speci-mens were collected for the determination of serum levels of IL-4 and IFN-γby double-antibody sandwich ELISA,while pancreas tissues were collected and the pathological changes were observed.Results The serum IL-4 level of B group [(23.87 ±4.85)pg/mL]was higher than C group [(4.39 ± 0.56 )pg/mL],with significant differences (P < 0.01 ),while the serum IFN-γ level [(271.85±26.04)pg/mL]was lower than C group [(362.79 ±32.50)pg/mL],also with significant differences (P <0.01).The serum IL-4 and IFN-γof A group were (5.09±0.37)pg/mL and (379.56±34.47)pg/mL,which had no difference with C group (P >0.05).The islet structure of mice in B group was not intact,however,the lymphocytic infiltration in B group was less than C group,and there was no lymphocytic infiltration in pancreatic islets in B group.Compared with C group,the pancreas of mice in A group did not have significant changes,lymphocytes infiltration was still visible in islets.The number of residual islet cells de-creased,and visible minority islet structure was destroyed.Conclusion SEA of Schistosoma japonicum has certain antagonism effect on type 1 diabetes in experimental mice.Its mechanism may be the reduction of Th1 response and the enhancement of Th2 response through increasing IL-4 level and decreasing IFN-γlevel.

The interventional therapy of chemoembolization is the first management of choice in treating unresectable hepatic carcinomas but with some side effects including liver function damage and bone marrow restraints which may affect the patients'life expectancy and living quality in the long run.The advancement of the combination of interventional treatment with Chinese drugs in managing liver carcinomas is a special presentation by the auther for further recommondation.

Objective To investigate the effect of SMAD3 knockout on the reproduction of male mice.Methods Adult wild type females were mated with knockout or wild type males;Testis were performed with HE and TUNEL staining;Cauda epididymal sperms were counted and analyzed with morphology and motility.Results Wild-type / knock-out pairs resulted in a pregnancy rate of 92% with an average litter size of 5.45? 0.78 and a live birth rate of(87?19)%.In the wild-type / wild-type pairs,100% females were pregnant,the litter size was 6.01? 1.03,and the live rate was(97?15)%,there was no significant difference between the two groups.Histological analysis showed a relatively normal spermatogenesis in knockout testis,and TUNEL analysis did not demonstrate more apoptotic cells in knock-out testis.The cauda epididymal sperm number was normal,and there was no obvious difference in the sperm motility and morphology in the knock-out males.Conclusion The function of SMAD3 can be compensated in male reproduction.

OBJECTIVE To analyze the reasons causing hospital infection in surgical intensive care unit(SICU) in order to make the intervention strategy.METHODS The underlying diseases,age,interventional manipulation and medical staff versus hospital infection and the status of pathogens in SICU were analyzed.RESULTS Severe diseases among old patients caused hospital infection easily.More times of interventional manipulation made the occurrence of hospital infection more frequent.The inappropriate use of antibiotics caused resistant pathogens.SICU established incorrectly and the lack of medical staff increased cross-infection possibly.CONCLUSIONS In order to control infection in SICU,the effective measures should be taken,including strengthening the regulations of administration about SICU,enhancing the antiseptic measures for severe patients,anddecreasing interventional manipulation.

Praziquantel is the only effective drug of choice against five huaman species of schistosomes. Main adva-ntages of praziquantel include convenient oral administration, high safety and efficacy as well as short treatment course. To better understand the mode of action of praziqantel against schistosomes would be helpful for further development of new broad-spectrum anthelminthics. This paper summarizes the 30 years′ research progress on the mode of action of the drug against schistosomes proceeded by domestic and abroad laboratories.

AIM: To analyze biomechanical characteristics after artificial intervertebral disc implantation. METHODS: A computer-based online search of Pubmed database and Chinese Journal Full-text Database was undertaken to identify articles about artificial lumbar intervertebral disc application. In addition, the articles published in authoritative journal in recent 5 years were selected firstly. Repetitive studies or Meta analysis were excluded. The references of each article were looked up, and summarized. RESULTS: ①Artificial intervertebral disc can rebuild and retain normal physiologic activities of spine. How to design the rotation center of each lumbar moving segment to make it move with flexion, extension, lateral flexion and rotation, and axial rotation along with lumbar lateral flexion. ②Although the material and design are different, current used several prostheses have common movement mechanism, i.e. ball-joint, similar to Fernst joint metal ball, which is not found in normal intervertebral disc. ③With the development of intervertebral disc replacement, it has become an novel technique to treat intervertebral lumbodorsal pain. Although many prosthesis is under exploration, some reports and short-follow up results have suggested intervertebral disc replacement retains spine activity, significantly relieves pain in short period of time, and improves life of quality. But the long-term follow up is little. CONCLUSION: It is documented that artificial intervertebral disc can remain enough height of intervertebral space and lumbar motion function. The short-term clinical outcomes are fair, but long-term effect still needs further clinical experiments and long-term follow up.