1.An Exploration of Medical English Teaching in Medical College
Chinese Journal of Medical Education Research 2006;0(08):-
The current situation demands that the medical English teaching in medical colleges should aim to cultivate more practical and professional medical staff.To improve teaching,the exploration was made and some suggestions were put forward.
2.Study of cognitive function impairment in 45 patients with epilepsy
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(10):-
Objective To investigate the characteristics of cognitive function impairment in patients with epilepsy. Methods Forty-five epilepsy patients and twenty age-,gender-,and education-matched healthy controls were submitted to a wide neuropsychological battery,including Raven's standard progressive matrices,auditory verbal memory test,logical memory test,visual memory test,Stroop color words test,trail making test,verbal fluency test,Boston naming test,math and complex figure test,etc. Results The epilepsy patients performed significantly worse than the controls in the verbal delayed memory,verbal short memory,cued recall,immediated recall of logical memory test,visual spatial memory,attention,information processing speed test,word finding difficulty and logical reasoning.Conclusion There exists impairment in various cognitive domains in patients with epilepsy,and the main impaired areas are memory,executive functions and logical reasoning.
3.Effect of ERK pathway inhibitor U0126 on cell cycle of leukemia K562 cell lines
Journal of Third Military Medical University 1988;0(05):-
Objective To study the mechanism of extracellular signal-regulated kinase (ERK) pathway inhibitor U0126 on cell cycle of K562 cell lines. Methods The mRNA and protein expressions of ERK, Cyclin D2, Cyclin E in and P27 K562 cell lines after 10 ?mol/L U0126 treatment for 12, 24 and 72 h were detected by RT-PCR and Western blot, respectively. The cell cycle was determined by flow cytometry. Results The mRNA and protein expressions of ERK, Cyclin D2 and Cyclin E in K562 cell lines after U0126 treatment were decreased, while those of P27 were increased. The percentage of cells in G0/G1 phase was increased and that in S phase was decreased. All data mentioned above showed significant difference between the K562 cell lines before and after U0126 treatment(P
4.Relationship of visual quality and postoperative dominant eye changes with age-related cataract
International Eye Science 2015;(5):866-868
? AlM: To investigate age - related cataract and its postoperative dominant eye changes and visual quality of patients.
?METHODS: Totally 102 patients ( 204 eyes ) with age-related cataract in our hospital from January 2013 to November 2014 were selected, and according to preoperative best corrected visual acuity ( BCVA ) were divided into two groups, in which the both eyes BCVA difference ≥2 lines ( 78 cases, 156 eyes ) was group A, and both eyes BCVA difference ≤1 line ( 24 cases, 48 eyes ) was group B. Dominant eyes were detected preoperatively and at postoperative 1 and 3mo. Contrast sensitivity and investigated visual satisfaction were tested.
?RESULTS: Preoperative dominant eye corrected visual acuity was 0. 34 ± 0. 11, significantly higher than that of the non-dominant eye (0. 15 ± 0. 09), and there was statistically significant difference ( P < 0. 05 ); At postoperative 1 and 3mo,between corrected visual acuity difference dominant eyes and the non-dominant eyes was not statistically significant ( P>0. 05 ); At postoperative 3mo, 17 cases in the group A had dominant eye changes, and change rate was 21. 79% (17/78). At postoperative 3mo, the dominant eye change rate in the group B was 20. 83% (5/24), and there was no statistical significant difference between the two groups ( P > 0. 05 ). The dominant eye change group and non- change groups patients with different spatial frequency contrast sensitivity test showed no statistical significance ( P >0. 05 ), Postoperative 3mo after operationvisual satisfaction questionnaire display, score of group A was (91. 35±10. 26) points, score of group B was (90. 15±9. 75) points (P>0. 05), the dominant eye change group score was (90. 08±9. 77) points, score non-change group was (91. 43±10. 22) points (P>0. 05).
?CONCLUSlON: The dominant eye changes exist in postoperative eyes with age-related cataract, but there is no effect on visual quality.
5.Research progress of miRNAs regulating TLRs signaling pathway in sepsis
Chinese Journal of Emergency Medicine 2016;25(12):1340-1343
Sepsis refers to the infection caused by systemic inflammatory response syndrome.Sepsis is one of the leading causes of death in critically ill patients in the ICU and its morbidity and mortality are increasing year by year globally.According to statistics,in China,the incidence of sepsis in ICU is 8.68% and the mortality rate can be as high as 44.7%,therefore,severe sepsis in the field of medicine to become one of the problems to be overcome.MicroRNAs (miRNAs) play an important role in the pathogenesis of sepsis through the TLRs / NF-κB signaling pathways,which play an important role in immune regulation.In this review,the progress of miRNAs involved in TLRs signaling pathway in sepsis is reviewed.
6.Review and Analysis of Processing Technology and Active Ingredients of Medicinal Leech
China Pharmacist 2014;(10):1760-1762
Theancientandmodernprocessingmethods,activeingredientresearch,andqualitycomparisonbeforeandafterthe processing of medicinal leech were reviewed in the paper. Combined with the results of anticoagulation test on Whitmania pigra Whit-man, the article drew a conclusion that different varieties of medicinal leech had different active ingredients of anticoagulation, Whitma-nia pigra Whitman had active ingredients of anticoagulation with promising heat stability, and the processing technology should be dealt with according to the clinic use.
7.Gut microbiota and nonalcoholic fatty liver disease
Journal of Clinical Hepatology 2017;33(4):774-779
Nonalcoholic fatty liver disease (NAFLD) is a common liver disease with multiple factors involved,and its incidence is gradually increasing around the world.Recent studies have found that gut microbiota is involved in the development and progression of NAFLD.This article summarizes the association between gut microbiota and NAFLD from the aspects of influencing factors for gut microbiota and the roles of gut microbiota and its metabolites in the development and progression of NAFLD and points out that the intervention of gut microbiota and its metabolites may be a new target for the prevention and treatment of NAFLD.
8.A case report of facial malignant granuloma.
Chinese Journal of Pediatrics 2004;42(3):165-165
9.Application of inquiring the real time ratio of patients and nurses in nursing human resource dynamic management
Chinese Journal of Practical Nursing 2013;29(36):5-7
Objective To discuss the application effect of real time ratio of patients and nurses in nursing human resource dynamic management.Methods Our hospital made full use of the information platform,inquiring the real time ratio of patients and nurses,in combination with mobile nurse library,implement dynamic vertical management of nursing human resources on the level of the hospital-wide nursing management.The overall manpower cost remained the same through internal reasonable adjustment to achieve the best configuration of human resources and met the clinical needs effectively.Results The running effect was satisfactory from July 2012 till now.All the mobile nurses allocated were 71 person-times and the satisfaction degree of patients increased to 97.96% in the first half of 2013.Conclusions Application of real time ratio of patients and nurses shows good effect,which is worthy of wide application.
10.Investigation and countermeasures of current situation of professional title and education back-ground of nursing human resourse in Liaoning province
Chinese Journal of Practical Nursing 2009;25(3):6-8
Objective To investigate and analyze the structure change of professional title and educa-tion background of nursing human resourse in Liaoning province in recent 3 years and raise up suggestions which suit for the structure and development of human resource of current nursing model. Methods Investi-gation scales for nursing human resource in Liaoning province were sent out to 85 hospitals in Liaoning province.SPSS 12.0 software was used to carry out statisdcal discription for these data. Results The main professional fide was primary. The main education background was junior college and technical secondary school in third-class hospitals and technical secondary school in second-class and first-class hospitals. Conclusions The professional title and education background of nursing human resourse in Liaoning province was not reasonable with imbalanced structure in various level of hespitals.The countermeasures included reform of nursing education, reasonable allocation and effective utilization of current nursing human resource and sys-tematization of continuing education.