Recently the National Science Foundation of China (NSFC) has put forward some measures to promote the development of women science and technology (S&T) talents.The paper analyzes the NSFC funded projects undertaken by women S&T researchers at Pekiing University Health Science Center from 2006 to 2010.To address the problems revealed in the analysis,the paper proposes the suggestions to further develop women S&T talents with the support of National Science Foundation of China.

This paper analyzes the distribution and achievements of the Science Foundation for Youth undertaken by female scientists at Peking University Health Science Center from 2002 to 2012.It reveals the importance of the Science Foundation for Youth in the development of female scientists.

OBJECTIVE:To investigate the effects of atorvastatin combined with valsartan on efficacy,safety and related indi-cators in patients with chronic nephritis. METHODS:86 patients with chronic nephritis were randomly divided into control group (43 cases)and observation group(43 cases). All patients were given low-salt,low-protein and high-quality diet with protein intake of 0.8 g/(kg·d),appropriately given Cyclophosphamide tablet,Prednisone tablet,Penicillin V potassium tablet and other conven-tional treatment. Based on it,control group was given 160 mg valsartan,once a day in early morning. Observation group was addi-tionally given 20 mg atorvastatin,once a day before bedtime. They were treated for 6 months. Clinical efficacy,24 h protein amount (24 h pro),serum creatinine (Scr),blood urea nitrogen (BUN),glomerular filtration rate (GFR),C-reactive protein (CRP),total cholesterol (TC),triglyceride (TG ),low density lipoprotein (LDL) and high density lipoprotein (HDL) in 2 groups were observed,and incidence of adverse reactions was followed-up for 9 months. RESULTS:The total effective rate in ob-servation group was significantly higher than control group,the difference was statistically significant(P<0.05). Before treatment, there were no significant differences in 24 h pro,Scr,BUN,GFR,CRP,TC,TG,LDL and HDL between 2 groups(P>0.05). After treatment,24 h pro,Scr,BUN and CRP in 2 groups were significantly lower than before,and observation group was lower than control group,GFR was significantly higher than before,and observation group was higher than control group,the differenc-es were statistically significant(P<0.05). TC and LDL in 2 groups were significantly lower than before,HDL was higher than be-fore,the differences were statistically significant(P<0.05);but there were no significant differences in the TG between 2 groups and before and after treatment(P>0.05). And there was no significant differences in the incidence of adverse reactions between 2 groups (P>0.05). CONCLUSIONS:Based on the conventional treatment,the efficacy of atorvastatin combined with valsartan is superior to valsartan alone in the treatment of chronic nephritis,and it can significantly improve renal functions,with similar short-term safety.

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Objective:To develop the attitudes toward gay men and lesbians in Chinese context.Methods:Based on the sex differences in homosexual researches and the three factors of attitude,the initial Scale included two subscales of gay men and lesbians,and selected items from cognition,emotion and behavior;used the initial scale firstly to test 353 college students,then selected items through 4 methods;secondly,investigated 404 college students and 533 community residents with the ultimate scale in order to assess it in reliability and validity,10 days after the first testing session,193 students were re-tested.Results:Developed the attitudes toward lesbians and gay men scale of 20 items;the test-retest coefficients of total-scale was 0.959,the Cronbach's ? coefficient of the total-scale was 0.898,the split-half reliability was 0.912.Factor Analysis indicated there were three components in the scale including moral judgement,emotional reaction,and social communication.Conclusion:The attitudes toward lesbians and gay men scale has a high reliability and a good validity and can be used in researches of the public Attitudes toward homosexual.

Objective To study Evaluation of serum soluble ST2 protein and brain natriuretic peptide(NT-proBNP)in patients with acute heart failure and prognosis of patients with acute heart failure.Methods Fifty cases patients with acute heart failure from April 2014 to April 2015 in the First Hospital of Traditional Chinese and Western Medicine of Beijing were researched.Detection of all patients with serum ST2,NT-proBNP,50 patients with acute heart failure were divided into heart failure group,50 healthy persons were selected as the control group.The control group and the observation group general heart failure data,the observation group and the control group of cardiac biomarker blood level,cardiac function level NT-proBNP blood concentration level,classification of cardiac function between ST2 blood concentration level were compared.Results Cr,BUN of heart failure group were higher than the control group,there was no significant difference between other indicators(P＞0.05).ST2((0.46±0.07)ng/L)in heart failure group was lower than the control group((0.66±0.20)ng/L),NT-proBNP((4160.20±57.49)ng/L)was higher than the control group((58.97±4.39)ng/L),heart function IV NT-proBNP blood concentration of the highest(9 428.29±75.93)ng/L,followed by grade III(1 921.01±30.27)ng/L,the second lowest(321.02±16.80)ng/L,(P＜0.01).Heart function IV level ST2 blood concentration was the highest(1.95±0.69)ng/L,followed by grade III(1.27±0.61)ng/L,class II minimum(0.78±0.24)ng/L(P＜0.01).Conclusion The serum ST2 and NT-proBNP are used to detect the patients with acute heart failure,can provide accurate diagnosis basis,has a very important value judgment on the classification and prognosis.

Sepsis refers to the infection caused by systemic inflammatory response syndrome.Sepsis is one of the leading causes of death in critically ill patients in the ICU and its morbidity and mortality are increasing year by year globally.According to statistics,in China,the incidence of sepsis in ICU is 8.68％ and the mortality rate can be as high as 44.7％,therefore,severe sepsis in the field of medicine to become one of the problems to be overcome.MicroRNAs (miRNAs) play an important role in the pathogenesis of sepsis through the TLRs / NF-κB signaling pathways,which play an important role in immune regulation.In this review,the progress of miRNAs involved in TLRs signaling pathway in sepsis is reviewed.

Objective To observe the effect of ShenQi Wuweizi Tablet (Tablet composed of pilose asiabell root, astragalus root, and schisandra fruit) on anxiety before college entrance examination.Methods Totally 227 patients were randomized into a treatment group (113 cases, treated with Shenqi Wuweizi Tablet, 3 tablets each time and 3 time a day), and a control group (114 cases, treated with alprazolam, 0.4 mg each time and 3 times a day). The treatment course was 6 weeks for both groups. Before treatment and at the end of the 1st, 2nd, 4th and 6th week of treatment, the clinical effect was assessed with Hamilton Anxiety Scale (HAMA) and Clinical Global Impression (CGI), and Self-Rating Anxiety Scale (SAS). And at the same time, the untoward reactions was also observed.Results At the end of the 1st week of treatment, the HAMA score was significantly decreased in the control group (P

Objective To discuss the MRI feature of meningeal metastasis and correlation of peritumoral brain edema and vascular endothelial growth factor(VEGF)expression.Methods 48 patients with meningeal metas-tasis were observed with plain and enhanced 1 .5 T magnetic resonance imaging scans,surgical removal of the tumor tissues was measured with VEGF immunohistochemistry.Results The patients with MC showed three types MRI fea-ture.The more vascular endothelial growth factor of the tumor tissues expressed,the more peritumoral brain edema (χ2 =33.34,P<0.01 ).Conclusion MRI scanning is necessary for clinical diagnosis in MC.There are positive correlation between the expression of vascular endothelial growth factor of the tumor tissues and peritumoral brain edema(P<0.01).

Thyroid cancer is the most common endocrine gland malignanct tumor. Numerous studies have found that the content of peripheral blood circulating RNA in various cancer types is aberrantly expressed, which could be a potential biological diagnostic marker and therapeutic target. Tissue-speciifc messenger RNA has a dysregulated expression and may be used for the diagnosis and residual/metastatic detection of thyroid cancer. Recent studies have showed that non-coding RNA (ncRNA) could act as oncogene or tumor suppressor gene in bacteria, fungi and mam-mals. It plays a regulatory role in occurrence and development of tumors and stably exists in peripheral blood. It is hopeful that it will become a new marker for diagnosis of tumors. This review introduces some latest research progress on circulating RNA associated with thyroid cancer; and emphatically discuss the role of mRNA, microRNA (miRNA), long non-coding RNA (lncRNA) and circular RNA (circRNA) in thyroid tumorigenesis and metastasis.