Objective To investigate the effect of Verisyse iris-claw intraocular lens implantation on correction of high myopia.Methods9 patients with highly myopic (18 eyes and diopter between-6.75 DS to-28.00 DS) were treated with Verisyse intraocular lens implantation. All the treated eyes were observed for uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure, anterior segment changes and corneal endothelium preoperatively and postoperatively.ResultsThe implantation was successfully performed in all of 18 eyes. After 3 months, 11 eyes (61.1%) had the uncorrected visual acuity (UCVA) ≥0.5; 9 eyes (50.0%) had the best corrected visual acuity (BCVA) ≥0.8. UCVA and BCVA of every eye were significant improved ( P<0.01); the mean corneal astigmatism and mean intraocular pressure were not different from preoperation ( P>0.05). In all patients, one eye was oval and 2 other eyes showed decentered phakic IOL; 2 patients (2 eyes) complained of halo and glare; no severe complications occurred.ConclusionThe implantation of Verisyse iris-claw intraocular lens for the correction of high myopia has a significantly effect.

ObjectiveTo study the effect of negative pressure suction during laser in situ keratomileusis (LASIK) on rabbit retinal structure.Methods32 New Zealand white rabbits were randomly divided into normal control, experimental control, negative suction 45 seconds and negative suction 3 minutes groups. Experimental control groups were treated only using eximer laser. In negative suction groups, rabbit eyes were suction for 45 seconds or 3 minutes by negative pressure generator. The tissues of optic nerve and retina both after negative pressure suction and of normal rabbit eyes were examined with electron and light microscope 0, 7, 14, 28 days after operation. ResultsThere was no change in the tissues of optic nerve and retina between normal control and experimental control. After the negative pressure suction for 45 s, the optic nerve and retinal cells changed lightly at different time point. After the negative pressure suction for 3 min, the optic nerve fibers and retinal cells changed sharply during postoperative instant to 14th days, which can be recovered until 28 days after operation.ConclusionUltrastructural changes of retina and optic nerve may be induced by acute intraocular pressure elevation caused by negative pressure suction during LASIK.