Objective To investigate the clinical features of children's acute appendicitis in order to reduce the misdiagnose rate.Method Collect and retrospective analyse 77 cases clinical data of children's acute appendicitis from January 2008 to December 2011 in our hospital.Results There are 77 cases abdominal pain,61 cases fever,48 cases vomiting in 77 children,22 cases(28.57％) misdiagnosis or missed diagnosis in total.17 cases with appendix perforation,the perforation rate is 22.07％.49 cases receive surgery,28 cases receive conservative treatment.All are improved and cured and discharged.Conclusions The main clinical features of children's acute appendicitis is abdominal pain,fever and vomiting.When clinical features is not classic,there is higher rate of misdiagnosis and missed diagnosis,especially for infants.Stress that for children with unreasonable abdominal pain and fever,it is necessary to check leukocyte,CRP and type-B ultrasonic,observe the abdominal sign continually,in order to diagnose and treat early.

Objective To investigate phthalate esters in the muscle tissues of fresh water fish in fishponds in Pearl River Delta and Hong Kong,China,Nov,2005.Methods The samples from Pearl River Delta and Hong Kong,China,were analyzed by capillary gas chromatography with FID detector through the procedure of freeze-dried,soxhlet extraction,decontaminating with alumina-silica gel columniation in Nov,2005.Results The concentration of six sorts of PAEs was detected.The concentration of DEHP was 16.10 mg/kg(dry weight),19.81 mg/kg and 11.03 mg/kg in crucian carp,grass carp and tilapia from Pearl River Delta,while being 35.97,37.98 and 26.12 mg/kg for the same species from HK respectively,but the DMP showed the lowest value,only about 0.54 mg/kg.The concentration of DBP and BOP ranged from 3 to 10 mg/kg.Conclusion The fresh water fish from Pearl River Delta were polluted by DEHP,DBP and BOP significantly and the level of pollution is different among various areas.

Objective To investigate the residues of antibiotics such as quinolones in fishes from Guangzhou aquatic products market.Methods The residues of three kinds of quinolones(NFLX,CPFX and ENFX) in four kinds of fishes collected from five agriculture products markets in Guangzhou were determined by RP-HPLC.Results NFLX was detected in all samples,ranged from 2.19-192.8 ng/g with the maximum concentration of 192.8 ng/g,the detection rate of CPFX was 40% with the average concentration of 4.34 ng/g,ranged form 0-25.36 ng/g,the detection rate of ENFX was 45% with the average concentration of 6.83 ng/g.Three kinds of quinolones were found with high detection rate in Micropterus salmoides and Anguilla japonica,the average detection rates of NFLX,CPFX and ENFX in muscle tissues of Micropterus salmoides were 100%,40% and 100% respectively,that in Anguilla japonica were 100%,40% and 80% respectively.Low rate of ENFX was found in Monopterus albus and Ctenopharyngodon idellus muscle tissues,the average detection rates were 20% and 10%.Higher pharmaceuticals concentrations were detected in the liver than those in the muscle tissue.Conclusion The residues of quinolones in the muscle tissue of fish sold in Guangzhou is considered eligible based on the related standards.

Objective To evaluate the clinical diagnostic criteria of latent autoimmune diabetes of adults(LADA).Methods A total of 268 subjects consisted of 168 patients with type 2 diabetes(T2DM) and of 100 normal controls were involved in the study.The body mass index(BMI) was calculated by formula(kg/m~2) and the levels of fasting blood glucose(FBG),postprandial blood glucose(PBG),fasting C-peptide(FC-P),postprandial Cpeptide(PC-P),GAD antibody(GADA),ICA,IAA and IA-2 antibody were detected. The patients with positive antibody in T2DM group were considered as LADA and the others in T2DM group still as T2DM.Results The GADA,ICA,IA-2 antibody and IAA antibody were detected in 21.18%,14.29%,1.19% and 0.60% of patients with T2DM,respectively.The indexes such as the age of onset ≤ 40 years old,overt symptom,ketosis,without chronic complication and hypertension,BMI90.00%).Conclusion The GADA is the most specific antibody in the diagnosis of patients with autoimmune diabetes.The indexes such as the age of onset≤40 years,overt symptom,ketosis,without chronic complication and hypertension,BMI

Objective To research the thickness of adults frontal bones in many parts and analyze the mean-ing. Methods We chose 130 dry skulls of the Chinese people including 70 male skulls and 60 female skulls and ver-tically devided the frontal bones according the devidement of the superciliary arch into 4 parts on average. Then we measured the thickness of the frontal squama,the frontal tuber,the forehead and temple,the superciliary arch,the or-bital surface and the frontal sinus using the ruler, vernier caliper and protractor. Results We got the thickness of the frontal squama,the frontal tuber,the forehead and temple,the superciliary arch,the orbital surface and the frontal si-nus and calculated the average datas. What's more,besides the thickness of the frontal tuber,forehead and temple,the superciliary arch had statistical significance(P < 0.05) between males and females, other parts of the frontal bones had no statistical significance(P>0. 05). Conclusion We measured the thickness of the frontal squama,the frontal tu-ber,the forehead and temple,the superciliary arch,the orbital surface and the frontal sinus and the datas will had good guiding roles to our department's work.

Objective:To compare the knowledge of endoscopic screening of gastrointestinal cancers between digestive healthcare workers and new chatbots (chatGPT and new Bing).Methods:A test with twenty-three questions of endoscopic screening of gastrointestinal cancers was conducted, focusing on the appropriate age of screening, high-risk factors, the follow-up time, and the advantages and risks of digestive endoscopy. Digestive healthcare workers were invited to complete the test through electronic questionnaires. New Bing and chatGPT were used to answer each question for 10 rounds. The primary endpoint was the correct rate of all answers. The answer accuracy between digestive healthcare workers and new chatbots were compared using variance analysis, and the factors that affected the accuracy of the answers in digestive healthcare workers were explored using univariate and multivariable liner regression analysis.Results:The results of the test completed by 76 digestive healthcare workers (21 residents, 28 digestive nurses, and 27 digestive doctors) were analyzed. The accuracies were 36.4%±10.9%, 34.5%±10.2%, 52.2%± 12.6%, 46.3%±9.8% and 67.1%±9.3% in residents, digestive nurses, digestive doctors, chatGPT, and new Bing, respectively, with significant difference ( F=22.6, P<0.001). The accuracy was highest in new Bing ( P<0.001). The accuracy was comparable between chatGPT and digestive doctors (LSD- t=-1.398, P=0.166), and both higher than that of digestive nurses (LSD- t=2.956, P=0.004; LSD- t=5.955, P<0.001) and residents (LSD- t=2.402, P=0.018; LSD- t=4.951, P<0.001). Furthermore, the accuracy was comparable between digestive nurses and residents (LSD- t=-0.574, P=0.567). Compared with new Bing, digestive doctors had lower accuracy in answering questions related to adverse events of screening, follow-up recommendation of intestinal metaplasia, high risk factors and screening methods for colon cancer ( P<0.05), but higher accuracy in answering questions related to endoscopic adverse events and screening methods for esophageal cancer ( P<0.05). Multivariable liner regression analysis showed that being digestive doctors ( β=11.7, t=3.054, P=0.003) and questionnaire response time (≥7.6 min) ( β=7.8, t=2.894, P=0.005) were independent factors for the answer accuracy of digestive healthcare workers. Conclusion:Compared with digestive healthcare workers, New chatbots—new Bing has higher accuracy in answering gastrointestinal cancer screening-related questions, but performs poorly in answering questions such as adverse events of endoscopy and screening methods for esophageal cancer.