1.Effect of propofol preconditioning on activities of ATPase on myocardial cell membrane in rats with myocardial ischemia-reperfusion injury
The Journal of Clinical Anesthesiology 2009;25(5):433-434
Objective To investigate the effect of propofol preconditioning on activities of ATPase on myocardial cell membrane in rats with myocardial ischemia-reperfusion injury. Methods Forty Sprague-Dawiey rats were subject to 30 min ischemia and 60 min reperfusion and randomly assigned to five groups, six rats per group: control(C) group; ischernia-reperfusion (IR) group; propofol preconditioning group(P, according to the dosage of propofol, P was assigned to three KM+-ATPase and Ca2+-Mg2+-ATPase of left ventricle myocardial tissue were measured by chemical colorirnetric method. The rnyocardium pathomorphism was observed with light microscopes. Results The activities of Na+-K+-ATPase and Ca2+-Mg2+-ATPase in ischemia-reperfusion group were lower than control group and propofol preconditioning group(P<0. 05 or P<0.01). Conclusion Propofol preconditioning can produced cardioprotective effect against ischemia-reperfusion injury by recovering the ATPase activities of myocardial tissue.
2."An interpretation of the newly revised standard on ""Definition and Demarcation of Water-borne Iodine-excess Areas and Iodine-excess Endemic areas"""
Qingzhen JIA ; Xiangdong ZHANG
Chinese Journal of Endemiology 2017;36(3):226-229
In order to solve some limitations and difficulties in guiding the practical work of determination and classification of the areas of high water iodine and the endemic areas of iodine excess goiter (GB/T 19380-2003),we carried out the revision on the original standard from 5 aspects such as the name,normative reference file,the definition and the technical indicators of classification of high iodine areas and the endemic areas of iodine excess goiter,such as sampling method in appendix and so on,and worked out the standard of definition and demarcation of water-borne iodine-excess areas and iodine-excess endemic areas.Enforcement of the new standard will bring important social benefits.
3.Development of vein image projection equipment
China Medical Equipment 2016;13(4):9-10,11
Objective:To introduce a method and theory about how implementation vein image projection epidermis and conduct the clinical testing.Methods: Base on existing electronic components construct circuit. The construct circuit was made of industrial personal computer, mini-projector, camera and so on. The image is captured by camera transfer to industrial personal computer. Choosing suitable image process algorithms modify image. Processed image that storage in industrial personal computer transfer to mini-projector, vascular vein lines is produced from mini-projector.Results: Through this way that vascular vein projector method get image basic agreement vascular trend, meet the clinical needs.Conclusion: Vein image projection methods meet clinical need can be used to study other field.
4.Tumor microenvironment: A novel target for antitumor activity of polysaccharides
Journal of China Pharmaceutical University 2010;41(1):1-10
Tumor microenvironment plays a crucial role in neoplastic evolution process as it may provide functional interactions between neoplastic and non-neoplastic cells involved in tumor invasion,metastasis and angiogenesis,which implies that it can be regarded as a novel target for the antitumor therapy of polysaccharides.This review focuses on the protumor variations existing in tumor microenvironment,such as growth factors,immunosuppressive factors,proteases,glycoproteins,etc.,which may offer possible mechanisms of polysaccharides on the regulation of their corresponding functions.
5.Clinical study of bacterial infection in patients with liver cirrhosis
Xiangdong LU ; Shiduo SONG ; Zhiguang ZHANG
Chinese Journal of Postgraduates of Medicine 2010;33(31):14-16
Objective To study the state, feature and risk factors of bacterial infection in patients with liver cirrhosis, find out the influence of infection on prognosis, and provide scientific basis for its prevention and treatment. Methods Three hundred and twenty-three patients with liver cirrhosis were analyzed. The number of the patients with infection, the location of infection, clinical feature as well as the kind of pathogenic bacteria were analyzed. Unconditional Logistic regression analysis was used to assess the risk factors of bacterial infection. Results The overall infection rate was 39.94% (129/323),of which community acquired infection rate and nosocomial infection rate were 22.60% (73/323) and 17.34%(56/323) respectively. The most common location of infection in turn were respiratory tract,gastrointestinal tract, urinary tract,biliary tract and abdominal cavity. The main pathogenic bacteria was Gram-negative bacillus, most of which had drug resistance for cefquinome and quinolones. The risk factors related with bacterial infection included liver cancer, Child-Pugh class B and C grade of liver function, gastrointestinal tract bleeding, diabetes mellitus,invasive operations and the length of staying in hospital. Conclusions The incidence rate of infection in patients with liver cirrhosis is higher. Multiple factors are likely to affect the incidence rate of infection in patients with liver cirrhosis.
6.Effects of Environmental Vibration on Human Health
Xiangdong ZHANG ; Jie GAO ; Weiming YAN
Journal of Environment and Health 1993;0(01):-
With the development of technology and economy, the whole living space has been filled with different vibration, the chance of exposure to vibration for people is on the increase. Environmental vibration is one of seven main pollutions in the world, people’s health is threatened. The main four factors effected human body vibration were introduced in this paper, and the adverse effects on the systems were discussed, the criterion of evaluating human response to vibration based on international and national standards were analyzed.
7.Biomechanical study and application of lateral-anterior internal fixation with TSRH in thoracolumbar fracture
Zhenhua JIANG ; Xiangdong CHEN ; Feng ZHANG
Orthopedic Journal of China 2006;0(06):-
0.05).[Conclusion]Lateral-anterior fixation with use TSRH not only has effective result in strength, rigidity and stability of the spine, but also is superior to the control group in loading-bearing ability and stability of the spine. There is no significant difference between the TSRH group and Z-plate group. But TSRH is relatively simple to operate and is cheaper than Z-plate, and has exact clinical ontcome.
8.Clinical application of single immediate implant-supported restoration in posterior mandible
Lei ZHANG ; Yongfu HOU ; Xiangdong WANG
Acta Universitatis Medicinalis Anhui 2016;51(6):865-867,868
Objective To evaluate the clinical effect of immediate implant restoration in lower posterior teeth . Methods 31 XIVE implants were placed in lower posterior teeth of 31 patients.The temporary fixed resin crowns were fabricated immediately and final restorations were finished in 3~4 months.The control group used nonsub-merged implants and were restored with final crowns in 3~4 months.The tracking survey was taken from 12 to 24 months after final restoration .The patient satisfaction , papilla index score ( PIS ) and implant survival rate were eval-uated between the two groups .Results PIS of patients with immediate restoration reached (2.35 ±0.70) in aver-age compared(1.84 ±0.74) in control group.The patient satisfaction reached (91.5 ±7.5) with immediate resto-ration, compared with VAS score in average of(85.8 ±8.1) in control group.All implants in both groups achieved osseointegration and received 100% survival rate .Conclusion With proper technique in surgical and restoration procedure , immediate restoration after implant insertion in posterior madible has similar clinical success compared with delayed restoration .
9.Impact of psychological disorder on treatment outcomes in patients with intractable Meniere's disease.
Xiangdong GUO ; Qinglin WANG ; Zhicheng ZHANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2014;28(13):992-994
Adult
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Female
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Humans
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Male
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Meniere Disease
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complications
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therapy
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Middle Aged
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Mood Disorders
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Treatment Outcome
10.The value of P_(300) in judging the true and false coma in patients with closed craniocerebral trauma
Xiangdong ZHAO ; Meilian ZHANG ; Bingling ZHOU
Journal of Clinical Neurology 1992;0(01):-
Objective To study the value of P 300 in judging the true and false coma in patients with closed craniocerebral trauma. Methods The latency and amplitude of abnormal P 300 evoked by visual (image) stimulation were compared and analyzed between 237 cases with closed craniocerebral trauma.which were divided into coma,non coma,false coma and noclear group.Results There was very remarkable diffe rence in the latency and amplitude of P 300 between coma group and non coma group ( P 0 05). There was remarkable difference between the cases whose coma histories were unclear and non coma ( P