Adult ; Coal Mining ; Humans ; Male ; Pneumoconiosis ; classification ; diagnostic imaging ; Radiography ; Reference Standards

Objective To explore the clinical curative effects of angiotensin Ⅱ 1 receptor blocker in treating primary hypertension and its effects on insulin sensitivity.Methods Eighty primary hypertension patients were divided into the treatment group ( 40 cases,treated with telmisartan ) and the control group (40cases,treated with amlodipine) by random digits table.The treatment period was 8 weeks.After treatment,the clinical curative effect and insulin sensitivity was compared between the two groups.Results In treatment group and control group,the total effective rate was 75.0％(30/40) and 72.5％(29/40),there was no significant difference (P＞ 0.05 ).Before treatment,the insulin sensitivity index ( ISI ) in treatment group and control group was -4.5 ±0.8 and -4.7 ±0.7 (P ＞ 0.05),after treatment,the ISI was -3.2 ±0.5 and -4.4 ±0.6 (P＜0.05).Conclusion The clinical curative effects of angiotensin Ⅱ 1 receptor blocker in treating primary hypertension are obvious,and may improve the insulin sensitivity.

Acupuncture Therapy ; instrumentation ; Adolescent ; Adult ; Aged ; Facial Paralysis ; therapy ; Female ; Humans ; Male ; Middle Aged ; Young Adult

Objective To investigate the effect of pre injection of penehyclidine hydrochloride on the airway gland secretion of children with laparoscopic inguinal hernia surgery under general anesthesia.Methods 72 cases of children undergoing laparoscopic inguinal hernia surgery under general anesthesia in pediatric surgery department in our hospital were selected and divided into two groups,grouped by random number table method,control group of 36 cases were treated with preoperative injection of atropine,the experiment group of 36 cases were treated with preoperative injection of penehyclidine hydrochloride.Heart rate on pre injection(T0),before induction of anesthesia(T1),five min after induction(T2),ten min after induction(T3)and extubation(T4),the airway gland secretion,respiratory function related indexes,and the incidence of adverse reactions were compared.Results Compared with the control group,re fixed rate of tracheal tube during operation and the incidence of choking tube at T4 time were lower,the levels of PIP、Raw were lower and the level of CL was higher on five min after intubation,the HR at T1,T2,T3,T4 time was lower,with statistical significance(P<0.05);the incidence of adverse reactions in the control group 30.56％was higher than the experiment group 11.11％,with statistical significance(P<0.05).Conclusion Pre injection of penehyclidine hydrochloride can inhibit airway gland secretion in children with laparoscopic inguinal hernia surgery under general anesthesia,protect the respiratory function,and does not increase heart rate,the safety was higher.

Objective To study the helicobacter pylori(HP)infection and incidence of motion sickness,and observe the improment of motion sickness symptoms of motion sickness group after eradication of helicobacter pylori. Methods Random drawing from chronic gastritis of digestive diseases outpatient spot in the crowd of 765 people, which were investigated through the age,job title,medical history,symptoms of motion sickness and 14 C -UBT test. 153 cases of motion sickness with 14 C -UBT test positive were observed before and after helicobacter pylori eradication of the change of motion sickness symptoms by using quadruple therapy in patients with helicobacter pylori eradication, results were analyzed according to the survey.Results 765 people,384 cases HP positive,HP total positive rate 50.20%.motion sickness occurred in 213 cases,motion sickness was 153 cases HP positive,HP positive rate 71.83%(153 /213);Without HP positive,231 cases of motion sickness,positive rate of motion sickness group were 41.85%(231 /552),which were similar between the two groups with statistically significant(χ2 =55.27,P <0.05). In the HP positive and carsick 153 cases,76 cases of using quadruple therapy for the eradication of helicobacter pylori,and motion sickness symptoms improved were 11 cases 1 years later.The eradication of helicobacter pylori was not used in 77 cases,in which motion sickness symptoms improved for 2 cases 1 year later.And the comparative difference was statistically significant(χ2 =6.94,P <0.05).Conclusion HP infection has certain correlation with the incidence of motion sickness,the eradication of helicobacter pylori may be beneficial to improve the symptoms of motion sickness.

Objective To explore the effect of methylprednisolone combined with interferon in the treatment patients with relapse remitting multiple sclerosis.Methods 90 patients with relapse remitting multiple sclerosis were randomly divided into experimental group and treatment group.The experimental group during the acute stage with methylprednisolone pulse therapy,remission with interferon β (IFN-β) treatment; the control group only in the acute phase with methylprednisolone pulse therapy.Results The total effective rate of methylprednisolone pulse therapy in the acute stage was 98.9％.Experimental group during the treatment with IFN-β1α,relapse rate was 30.2％ ;patients in the control group were followed up for two years,the recurrence rate was 53.3％.Experimental group and control group was significantly different ( P ＜ 0.05 ),the experimental group was significantly lower than the control group.Conclusion For relapsing-remitting MS,using MPPT could relieve acute symptom in the acute stage,and in remission using of IFN-β1α relapse prevention was a good choice for clinicians.

As a mode of pay for performance,hospital value-based purchasing has been become widespread the US.Medicare managed to encourage the service providers to provide medical services with more value and quality.The implementation background,financing,payment mode and performance evaluation of hospital value-based purchasing were briefly introduced.In the payment reform of China,it also needed to focus on the medical service quality,learn from the performance evaluation system,incentive mechanism and multiple measurement,reasonably design the implementation scheme.

Objective To analyze the status of Huangshui River water pllution by chromium(Cr6+)and define the pollution source. Methods Water samples were collected from 5 monitoring points closely located at the bank of Huangshui River from the upper reaches to the lower reaches including A spring,Huanghai canal,Duoba water source well,Zhamalong,Xigangqiao,and also from the location of the upper reaches of Halejian River in the area of source of Huangshui River established as the control monitoring point during 1996-2003. The contents of Cr6+ in the water samples from above sampling points were determined. Results During 1999-2003,the average content of Cr6+ in the water samples from A spring was 45.192 mg/L,and those from Huanghai canal in the upper reaches of Huangshui River Zhamalong and Xigangqiao increased year by year gradually.By the end of 2003,Cr6+ hadn't been found in the water samples from the upper reaches of Halejian River,but Cr6+ had been found first in the water samples from Duoba water source well with a concentration of 0.007 mg/L. Conclusion Haibei Chemical Industrial Works near A spring was the main source for the Cr6+-pollution of water body of the upper reaches of Huangshui River.

By improving the existing pattern that different medical institutions with competition fragmentary health care mode,the bundled payment could improve the coordination and cooperation between medical institutions,improve the overall medical service quality and reduce medical service cost.It provided a helpful thought for the supply-side reform in health field in China.Foreign experience indicated that in order to implement bundled payment mode,China should build a complete medical service supply chain to promote integration of medical institutions;shift economic stimulus to economic constraints,build orderly competition environment;strengthen the construction of informatization and promote the applications of healthy big data.

Objective:To compare the effects of XELOX (oxaliplatin + capectabine) regimen and FOLFOX4 (oxaliplatin + calcium leucovorin + fluorouracil) regimen on colon cancer and their influences on serum tumor markers and cytological indexes.Methods:A total of 84 patients with colon cancer treated in Wuhu Hospital of Chinese Medicine of Anhui Province from January 2016 to January 2019 were selected, and the patients were randomly divided into the observation group (XELOX regimen, 42 cases) and the control group (FOLFOX4 regimen, 42 cases) according to the random number table. The efficacy, side effects, the changes of cytological indicators and serum tumor markers before and after chemotherapy between the two groups were compared.Results:The short-term effective rate was 76.19% (32/42) in the observation group and 61.91% (26/42) in the control group, and the difference was not statistically significant (χ 2 = 2.005, P=0.156). The incidence of side effects in the observation group was lower than that in the control group [35.71% (15/42) vs. 59.53% (25/42), χ 2 = 4.773, P = 0.029]. There was no significant difference in the levels of carbohydrate antigen 199 (CA19-9), colon cancer-specific antigen (CCSA-2) and osteopontine (OPN) between the two groups before treatment (all P > 0.05); after treatment, CA19-9, CCSA-2, OPN levels were lower than those before treatment of the two groups (all P < 0.05); after treatment, CA19-9, CCSA-2, OPN levels in the observation group were lower than those in the control group (all P < 0.05). Before treatment, there was no significant difference in the levels of neutrophils to lymphocytes ratio (NLR), platelet-lymphocytes ratio (PLR), and red cell distribution width (RDW) between the two groups (all P > 0.05); the levels of NLR, PLR and RDW after treatment in the two groups were decreased compared with those before treatment (all P < 0.05); NLR, PLR and RDW levels in the observation group after treatment were lower than those in the control group (all P < 0.05). In the observation group, the recurrence rate of 1-year, 2-year, 3-year was 4.76% (2/42), 14.26% (6/42), and 19.05% (8/42), respectively; in the control group, the recurrence rate of 1-year, 2-year, 3-year was 11.90% (5/42), 21.43% (9/42), and 26.19% (11/42), respectively; there was no statistical difference between the two groups (all P > 0.05); in the observation group, the survival rate of 1-year, 2-year, 3-year was 92.86% (39/42), 78.57% (33/42), and 71.43% (30/42), respectively; in the control group, the survival rate of 1-year, 2-year, 3-year was 85.71% (36/42), 69.05% (29/42), and 64.28% (27/42), and there was no statistically significant difference between the two groups (all P > 0.05). Conclusions:XELOX regimen and FOLFOX regimen have similar short-term and long-term effects on patients with colon cancer. They both can decrease the levels of serum tumor markers and cytological indicators of patients, and improve their prognosis, while XELOX regimen has low side effects.