2.Rapamycin for myeloid blast crisis in refractory chronic myeloid leukemia with imatinib-resistance.
Jing XIE ; Xiang ZHANG ; Bao-Zhi FANG
Chinese Journal of Hematology 2011;32(8):553-554
Adult
;
Antibiotics, Antineoplastic
;
therapeutic use
;
Benzamides
;
Blast Crisis
;
drug therapy
;
Drug Resistance, Neoplasm
;
Humans
;
Imatinib Mesylate
;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
;
drug therapy
;
Male
;
Piperazines
;
pharmacology
;
Pyrimidines
;
pharmacology
;
Sirolimus
;
therapeutic use
3.Endoscopic and clinical features of ischemic colitis
Ping XIANG ; Zhijun BAO ; Fuxing XU
Chinese Journal of Digestion 1998;0(06):-
Objective To evaluate clinical and endoscopic characteristics of ischemic colitis (IC), and to explore the methods for the early diagnosis of IC. Methods Thirty six patients diagnosed as IC in Hua dong Hospital from June 1975 to December 2000 were reviewed. All patients underwent colonoscopy with biopsy within 5 days of symptoms, and repeated the exam in 2 weeks to 2 months. Results Of the 36 cases (12 men and 24 women, average age 60.5 years old, range 35 84), 31 were over 50 years of age. IC usually presented with sudden onset of left lower quadrant abdominal pain, diarrhea and hematochezia. Patients' ischemic lesions were most often on the left colon. It consisted transient or reversible colitis in 30 cases, stricture colitis in 5 cases and gangrene colitis in only 1 case. Morphologic changes varied with the duration and severity of the injury. Conclusion Colonoscopy with biopsy is the main method for the diagnosis of IC. It should be performed in the early stage of the onset of symptoms.
4.Advances on Polyketide Biosynthesise by Microorganism and the Diversity of Polyketide Synthases
Li-Cheng REN ; Shi-Xiang BAO ;
Microbiology 1992;0(01):-
Polyketides are very large group of natural products with functional and structural diversity.Most of them are produced by microor- ganism and have medicinal activities,including antibiotic,anticancer,antifungal and antiparasitic properties.The researchs in this area have progressed greatly.More and more polyketides are discovered,on the other hand the mechanisms of biosynthesis of those various polyketides are researched more deeply and clearly.The article reviewed the progress of the research in the diversity of polyketide synthases and the mechanisms of polyketide biosynthesise.
5.The concept of scientific development as a guideline for hospitals reform and development
Yurong BAO ; Shijun ZHU ; Dong WANG ; Xiang LIU ; Guiyun ZHANG
Chinese Journal of Hospital Administration 2009;25(1):1-4
Thanks to the three decades of reform and opening up,hospitals in China have made tremendous achievements in their development,yet facing new ehallenges as well.to address these challenges,there is an urgent need for these hospitals to further their reform under the guideline of the scientific concept of development.This will help them strengthen their hospital culture,quality control,technology,human resources development,and their leadership,in order to achieve a better and faster growth,better serving the role to build a harmonious socialist society.
8.Comparative analysis between breast conventional mammography and amplificatory mammography with partial compression in 65 cases of breast cancer
Huaxiu DUAN ; Chunlin ZHAO ; Xiang BAO ; Qun SHI
Chinese Journal of Primary Medicine and Pharmacy 2014;21(11):1674-1675
Objective To discuss the correlationship between the diagnosis of surgical pathology and the signs of malignancy which is both displayed by breast conventional mammography and amplificatory mammography with partial compression.Methods 65 cases with breast cancer were examined by both breast conventional mammography and amplificatory mammography with partial compression.The results of the two methods were analyzed.Results In all 65 cases of breast cancer,the comparison between breast conventional mammography and amplificatory mammography with partial compression could provide 16/60 cases in the X-ray signs of malignancy,which were in accordance with pathological examination results,19/41cases in the occurrence of calcification,13/37 cases in ductal calcification,0/4 cases in mixed type calcification,18/46 and 14/59 cases in the occurrence of lobulation and spicule signs.Conclusion Amplificatory mammography with partial compression can provide better insight in breast cancer than conventional mammography,especially in the region of dense shadow,small calcification and dense breast lesions,amplificatory mammography with partial compression can provide higher accuracy in diagnosis,especially for early breast cancer.