Acute Disease ; China ; Humans ; Insecticides ; poisoning ; Organophosphate Poisoning ; Poisoning ; prevention & control

Humans ; Occupational Diseases ; diagnosis ; Reference Standards

Accidents, Occupational ; prevention & control ; Humans ; Metals ; poisoning

Construction of knowledge service system for university students'innovation and undertaking training program was proposed by analyzing their difficulties in information access during innovation and undertaking train-ing.The key points in constructing knowledge service system were pointed out, namely establishing professional service teams, providing stereoscopic and diversified service, establishing feedback and evaluation systems, and building powerful platform for information exchange.

Early diagnosis and treatment can improve the outcomes of patients with gastrointestinal neoplasms. Although digestive endoscopy is considered as a best method to diagnose gastrointestinal neoplasms,some early stage,flat-type neoplasms may be overlooked by routine endoscopy. In recent years,endoscopic autofluorescence imaging( AFI)as a new technique, has been widely applied in clinical practice for enhancing the endoscopic diagnostic accuracy of gastrointestinal neoplasms,especially for early stage,flat-type neoplasms. This article reviewed the clinical application of AFI for diagnosis of gastrointestinal neoplasms.

Recently,the interest in a new surgical procedure named natural orifice transluminal endoscopic surgery has blossomed worldwidely.During these several years,quite a number of natural orifice transluminal endoscopic surgery experiments have been carried out on porcine models and even on humans,including transvaginal cholecystectomies,transgastric appendectomies,transvaginal appendectomies,transvesical peritoneoscopies,etc.This review article aims to discuss the current research status and the challenges of orifice transluminal endoscopic surgery.

Etiologic classification of ischemic stroke is the basis for epidemiological investigation, risk factor screening developing individualized treatment plan and prognostic measures. The etiologic classifications, such as TOAST, CCS, and ASCO, are more generally accepted methods at present. This article reviews the advantages and disadvantages from the diagnostic criteria and clinical application.

Endothelial monocyte-activating polypeptide-Ⅱ (EMAP-Ⅱ ) is a novel proinflammatory cytokine with proinflammatory,proapoptotic and antiangiogenic properties.It is associated with many tumorassociated proteins,such as tumor necrosis factor,vascular endothelial growth factor,hypoxia inducible factor-1α,arginyl-tRNA synthetase,and insulin-like growth factor- Ⅰ.EMAP-Ⅱ has anti-tumor properties and has a good prospect in cancer prevention and treatment.

Bacillus anthracis , the aetiological agent of anthrax, was the first discovered pathogenic bacterium in history Rapid progresses have been made on this field in recent years, especially; Bacillus anthracis has been sequenced successesfully early this year and published on the Internet The anthrax pathogenesis is always central to the study and there has been an enormous amount of work to elucidate it In this review, we will focus on the latest findings that concern three aspects of anthrax pathogenesis: Bacillus anthracis genome, pathogenic substances and pathogenesis mechanism

DNA methylation is one of the most common epigenetic events in eukaryotic cell.Aberrant DNA methylation is tightly related to tumorigenesis.Recent evidence indicates that DNA methylation is a promosing biomarker for cancer.The cancer-associated DNA methylation events could be detected from serum(plasma),urine,stool and bronchoalveolar lavage,providing a new choice for noninvasive cancer diagnosis.In this review,we summarized the advances on DNA methylation for noninvasive cancer diagnosis.