1.Design and application of medical banking system in class A tertiary hospital
Liwei CHEN ; Jian ZHANG ; Xianbin CAO
Chinese Medical Equipment Journal 2017;38(2):72-75
Objective To design a medical banking system to realize self register,self settlement,self printing and etc so as to enhance the efficiency.Methods The system was composed of a outpatient self-service sub-system,a hospitalization self-service sub-system,an appointment register sub-system by network bank,a cellphone App for self service,a comprehensive supervision and management platform for self-service system and self-service terminals,which had the functions such as hospital outpatient service,hospitalization self service and background supervision and management.Results Fulfilled the requirements of the patient on self register and settlement,and decreased the workloads of medical staffs.Conclusion The satisfaction over hospital service is enhanced greatly,and the system is of great value for practical application.
2.The retrospective study of 653 cases of influenza erupting prevalence
Xinghua WANG ; Xianbin CAO ; Mingmin WANG
Chinese Journal of Practical Internal Medicine 2001;0(03):-
Objective To investigate the clinical characteristics and prevalent features of an influenza erupting prevalence.Methods All of 653 patients with an erupting influenza were enrolled in the study from May 29,2003 to July 3,2003. The data included clinic manifestations and etiology. The retrospective study was used to evaluate the clinical and prevalent features. Results All patients consisted of 392 boys and 261 girls aged 5~17 years(mean 11.5 years),who were all students in middle school or primary school. Most of the patients had no typical symptoms including chill(2.45%),headache(30.00%),tiredness(10.87%)and the aching in whole body(4.44%),whereas fever,faucial inflammation and lymphatic follicular hyperplasia of the faucial posterior wall were the most common among these patients,accounting for 100%,60.03%,64.78% respectively. There were 98 patients whose peripheral leukocyte amounts were increased,most happening on the 6 ~7 th day from the onset(75.51%)following the fever on the 5~6 th day(80.6%). Detection of serum double virus-antigen indicated that influenza virus antibody increased more than 4-fold,as well as parainfluenza virus and adenovirus. Even in minority patients,there were several kinds of virus antibody raised 4-fold at the same time. We applied antivirus allopathy associated with the Chinese traditional medicine such as injection of shuanghuanglian or yuxingcao,plus the effectual antibiotics when necessary . All of the patients were cured and no sequelae. Conclusion Sometimes the influenza is prevalent only in some special crowds and has no typical symptoms such as chill,headache,tiredness and the aching in whole body.The antibiotics should be used in time after the synthetic treatment has no effect,when the patient has the onset for more than 5 days and has the fever for more than 4 days.
3.SM-1 induces apoptosis of BGC-823 cells by activating procaspase-3 and exerts antitumor effect
Hongzhong YUAN ; Yuting CAO ; Linna LI ; Shanshan WANG ; Dexuan YANG ; Xianbin ZHONG ; Shengbin TANG ; Shoujun YUAN
Military Medical Sciences 2016;40(4):326-330
Objective To investigate the antitumor activity of the procaspase-3 activator SM-1 in BGC-823 cells in vivo and in vitro and the mechanisms.Methods The inhibitory effects of SM-1 on proliferation of BGC-823 cells were evaluated using MTT method, the cell apoptosis rate was detected by flow cytometry, and the expression of caspase-3 protein and procaspase-3 mRNA was detected by Western blotting and RT-PCR, respectively.SM-1 Antitumor activity was evaluated using the xenograft of BGC-823 cells in nude mice.Results SM-1 effectively inhibited the proliferation in vitro and in-duced apoptosis of BGC-823 cells in a dose-dependent manner.After treatment with SM-1 for 48 h, the protein expression levels of caspase-3 and mRNA expression levels of procaspase-3 were increased.SM-1 significantly inhibited growth of BGC-823 xenograft tumor at the 300 mg/kg dose and the inhibition rate was 56.3%(P<0.05).Conclusion SM-1 can significantly inhibit the tumor growth of BGC-823 cells in vivo and in vitro.The mechanism is possibly related to the activation of procaspase-3 and induced apoptosis of tumor cells.