Objective To evaluate the quality of life for tuberculosis patients after anterior debridement, autograft bone fusion and anterolateral fixation operation. Methods 17 cases of thoracolumbar spinal tuberculosis were treated surgically from January 2008 to March 2011. All the cases underwent anterior debridement, autograft bone fusion and anterolateral fixation operation. MOS health survey 36-item Short Form (SF-36), Japanese Orthopaedic Association Scores (JOA) and Visual Analogue Scale (VAS) were used to evaluate the quality of life, spine function and pain symptom before and 1 and 6 months after surgery. Results Compared to the results 1 month after surgery, the scores of physical function (PF), role physical (RP), bodily pain (BP), general health (GH), vitality (VT), social function (SF), role emotional (RE), and mental health (MH), and JOA subjective symptoms, JOA clinical signs, and JOA daily activity limitation, and VAS improved (P<0.05) 6 months after surgery; compared to pretreatment, the scores of PF, BP, GH, VT, SF, and MH, and JOA subjective symptoms, JOA clinical signs, and JOA daily activity limitation, and VAS improved (P<0.05). Conclusion The anterior debridement, autograft bone fusion and anterior fixation operation is effective to improve the quality of life, spine function and pain symptom for tuberculosis patients.

Objective　To explore the clinical characteristics and drug resistance of Elizabethkingia meningoseptica (EM) nosocomial infection, so as to provide evidence for prevention of EM nosocomial infection and guiding the rational use of antibiotics. Methods　A retrospective study was conducted of 67 patients with EM infection in a tertiary hospital from January 2021 to December 2022. The infective characteristics and drug resistance were analyzed. Results　The cohort of 67 EM-infected patients was predominantly males aged ≥60 years, with the most frequent source being the first district of the intensive care unit (ICU), followed by the respiratory medicine and emergency department (19.40%, 13/67). The specimens were mainly isolated from respiratory tract (86.57%, 58/67), of which sputum accounted for 49.25% (33/67), and alveolar lavage fluid accounted for 37.31% (25/67). The majority of EM infections occurred in patients with pre-existing respiratory conditions (49.25%, 33/67), who generally experienced prolonged hospital stays and underwent invasive procedures, such as mechanical ventilation 94.03% (63/67), urinary catheterization (95.52%, 64/67), and central venous catheterization (97.01%, 65/67). Post-treatment, the improved rate of the 67 patients was 40.30% (27/67). Susceptibility testing demonstrated a high resistance rate of EM to cefoperazone-sulbactam, 98.39% (61/62), contrasted by significant susceptibility to compound trimethoprim-sulfamethoxazole (TMP-SMX)/cotrimoxazole, doxycycline, minocycline, and piperacillin-tazobactam, with susceptibility rates exceeding 90%. Conclusions　The patients infected with EM were almost elderly men with certain underlying diseases, experienced prolonged hospital stays, and had a history of invasive operations. The specimens of EM were mainly from Intensive Care Unit and isolated from respiratory tract. The strain showed high resistance to cefoperazone-sulbactam, whereas it remained highly susceptible to cotrimoxazole, doxycycline, minocycline and piperacillin-tazobactam, which may be considered as first-line treatment options.

Objectives:To investigate the effect of polyester filament fiber surgical drape in neurosurgery.Methods:A total of 181 neurosurgical surgeries were selected from April to July 2019 in a first-class general hospital. They were randomly divided into 2 groups, cotton group (92 cases) were covered with cotton drape, polyester filament fiber group (89 cases) were covered with polyester filament fiber. The anti-permeation performance, incidence of intraoperative hypothermia, and incidence of postoperative surgical site infection (SSI) between the two groups were compared.Results:At the end of the operation, the wetting rate of the cotton draped was 58.7% (54/92) and that in polyester filament fiber was 15.7% (14/89), with statistically significant differences ( χ2 value was 35.605, P<0.05);The incidence of intraoperative hypothermia was 22.8% (21/92) in the cotton group and 11.2% (10/89) in the polyester filament fiber group, with statistically significant differences ( χ2 value was 4.281, P<0.05). The incidence of SSI in the cotton group was 16.3% (15/92) , while that in the polyester filament fiber group was 6.7% (6/89) , with statistically significant differences ( χ2 value was 4.034, P<0.05). Conclusions:In neurosurgical operations with a long operation time and a large amount of irrigation fluid during the operation, using the polyester filament fiber drape can prevent the irrigation fluid from wetting the surgical drape, protect the surgical incision better, reduce the incidence of SSI and intraoperative hypothermia to some extent.