1.Evaluation on radiation protection and performance test for 192Ir brachytherapy apparatus
Zhu LIN ; Xiuru CHEN ; Wuzhe ZHANG
China Medical Equipment 2015;(6):31-33
Objective: To evaluate the radiation protection and performance test for the 192Ir brachytherapy apparatus. Methods: According to the national standard, radiation protection and its various properties of the 192Ir brachytherapy apparatus were tested. The radiation leakage dose of the 192Ir brachytherapy apparatus and the radiation scattered dose of the surrounding environment were tested with the ion chamber survey meter 451P. The activity of 192Ir radiation source was calibrated with the well chamber HDR1000 Plus. Results: The radiation leakage and scattered dose of the 192Ir source storage device and the surrounding environment are far below the national standard. The deviation of the activity calibration for 192Ir source is-2.07%, accordance with national standard±5%. Conclusion: Radiation protection and its various properties of the 192Ir brachytherapy apparatus should be regularly monitor for assuring the quality of the brachytherapy.
2.Relationship between HDL subclass distribution and plasma glucose and lipid levels in patients with metabolic syndrome
Mengxia QIU ; Shiyin LONG ; Zhijun CHEN ; Hao CHEN ; Wuzhe CHEN ; Yan ZHU ; Yanni MA ; Caiping ZHANG ; Ying TIAN
Chinese Journal of Pathophysiology 2015;(2):319-324
AIM:To investigate high-density lipoprotein ( HDL) subclass distribution and to analyze the rela-tionship between HDL subclasses with plasma glucose and lipids in metabolic syndrome ( MS) .METHODS:Apolipopro-tein A-I ( apoA-I) contents of plasma HDL subclasses were determined by two-dimensional gel electrophoresis associated with immunodetection .The concentrations of lipids and apolipoproteins in the plasma were measured by an automated bio -chemical analyzer .RESULTS:Compared with the controls , the levels of fasting plasma glucose ( FPG) , total cholesterol (TC), triglyceride ( TG), low-density lipoprotein cholesterol ( LDL-C), LDL-C/high-density lipoprotein cholesterol (HDL-C), apolipoprotein B100(apoB100), apoB100/apoA-I, systolic blood pressure (SBP), body mass index (BMI) and HDL3b were increased in the MS patients (P<0.05).Meanwhile, HDL-C, apoA-I and preβ2-HDL, HDL2a and HDL2b were decreased in the MS patients (P<0.01).With the increase in the plasma glucose level , the contents of HDL2a and HDL2b were decreased in the MS patients (P<0.05), while preβ1-HDL was increased (P<0.05).With the decrease in the HDL-C level, the content of HDL2b was decreased in the MS patients (P<0.01), while preβ1-HDL was increased (P<0.01).With the increase in the TG level and the decrease in the HDL-C level, the content of HDL2b had a decrea-sing trend and the content of small-particle preβ1-HDL had an increasing trend , indicating that HDL maturation metabolism was disrupted.The correlation analysis showed that FPG was negatively correlated with the levels of HDL 2a and HDL2b, HDL-C was negatively correlated with the level of preβ1-HDL and positively correlated with the level of HDL 2b , and TG was positively correlated with the levels of preβ1-HDL and HDL3b .CONCLUSION:With the increases in the plasma glucose and TG, and the decrease in HDL-C in the MS patients, HDL particles have minifying tendency , and the maturation me-tabolism of HDL particles is disrupted .