CT findings of seventy seven cases in sixty six patients were compared with the conventional radiographicfindings to evaluate the utility and the merits of the high resolusin CT in trauma, The resuls were as follows: 1.CT was helpful in the management in 50 cases(64%) of total 77 cases. 2. CT was useful in detection and evaluationof traumatic lesion in shoulder, wrist and ankle as well as spine, pelvis, hip and knee. 3. In difficultdiagnostic dilemas in trauma of the bones and the joints with the complex anatomy, CT should be consideredroutinely when appropriate.
Ankle ; Hip ; Humans ; Joints ; Knee ; Pelvis ; Shoulder ; Spine ; Wrist

CT from fortynine patients with 53 surgical disc explorations were reviewed and correlated with surgicalfindings. The results were as follows: 1. Frequent locations of HNP were in L4–5 (65%) and L5-S1(31%). The mostcommon type of HNP was paramedian type (71%). 2. Focal protrusion of the posterior margin of disc and obliterationof epidural fat pad were observed in all of cases (100%) and other common findings were indentation of epiduralsac in 46 cases(96%) and compression of nerve root sleeve in 33 cases(69%). 3. Cephalad and caudad extension ofproturded soft tissue density in the spinal canal was observed in 15 cases (31%) with variable degree. And morethan 6mm extension were provided to be extruded disc in 9 cases. 4. Vacuum phenomenon was demonstrated in 5cases(10%) and was accompained with bulging annulus. 5. Forty eight herniated nucleus(HNP) were confirmedsurgically in 44 patients. Misinterpretations were made in 4 instances(4 patients); 1 because of lumbar scoliosis,1 because of spondylolisthesis, and the other 2 because of calcified posterior longitudinal ligament and bulgingannulus. One case of true negative examination was central and foraminal stenosis in spinal CT. Thus, sensitivity,specificity and overall accuracy of lumbar spine CT in HNP were 92%, 100% and 92%, respectively.
Adipose Tissue ; Constriction, Pathologic ; Humans ; Longitudinal Ligaments ; Spinal Canal ; Spine ; Spondylolisthesis ; Vacuum

Genetic mutations in endometrial cancer (EC) have been extensively studied in the Western population but not much in Asian cohorts. This study has demonstrated that PTEN and PIK3CA mutations are commonly found in EC among Malaysian women. Following RNA extraction from 20 cancerous and 18 non-cancerous tissues, the presence of mutations in 9 exons of PTEN and 3 exons of PIK3CA genes were detected using realtime PCR, accompanied by High Resolution Melt (HRM) analysis. Sequencing confirmed specificity of each PCR product. The mutations for both genes were detected in the samples with varying frequencies. Notably, all samples expressed mutation of PTEN at exon 7 but none in exon 4. Further analysis demonstrated that strong concurrent mutations occurred between exons 7 of PTEN with exon 20 region 1 of PIK3CA gene (90%). Our data showed mutations are present in EC and not the non-cancerous tissues. Larger samples are being collected to validate this observation.
Uterine Neoplasms

Background: Dermatophyte infection is one of the most common skin diseases affecting the skin, hair, and nails. Despite widespread recognition of the disease, missing details and misperceptions are commonplace in the general population. Objective: This study aimed to investigate the public perception and behavior regarding dermatophytosis of the hands and feet. Methods: This results from an online survey conducted between July 2022 and August 2022. The survey included 1,000 Korean participants aged 20 to 69 years, of whom 60% experienced symptoms of tinea pedis or onychomycosis. The questionnaire focused on the awareness and personal experience of tinea pedis and perception of the treatment of dermatophytosis. Results: Of the 1,000 participants, nearly 80% regarded tinea pedis as a common skin condition by which anyone can be affected. Furthermore, 88.4% had heard that the treatment of tinea pedis could be harmful, causing skin rash (60.4%) and worsening liver function (48.5%). Among 896 participants who noticed suspicious symptoms, 81.2% did not visit the clinic because it was not severe (50.1%) and seemed easily manageable (25.7%). Of the respondents, 84.4% preferred to meet dermatologists rather than non-dermatologist doctors regarding skin diseases, mainly because of trust in experts and belief in a faster cure. Conclusion Providing accurate and detailed information via online media, educational campaigns, and medical papers can rectify misconceptions and improve patient appliance, contributing to public skin health.