Background and Objectives: Fire events emit pollutants that affect both air quality and respiratory health. This paper analyzed the interrelationship of satellite-derived fire spot density and annual average particulate matter (PM₂.₅) concentrations with the incidence of respiratory diseases. Methodology: Monthly cases of influenza-like illness (ILI) and pertussis for 2017-2018 in all 17 regions of the Philippines were accessed from the Department of Health (DOH) Epidemiology Bureau. Reported cases per 100,000 population in the Philippines were linked with regional fire spot density and annual mean PM₂.₅ estimates from satellite data, Visible Infrared Imaging Radiometer Suite (VIIRS) active fire data, and Modern-Era Retrospective Analysis for Research and Applications, version 2 (MERRA-2), respectively. Linear, logistic, and Poisson models were used to analyze the association between the exposure and outcome variables. Results and Discussion: The highest PM₂.₅ concentrations were observed in Regions IV-A and NCR but fire spot density was relatively lower. High PM₂.₅ levels can be due to other sources in these largely urbanized regions, such as vehicular emission, among others. Similarly, results showed inconclusive association between atmospheric parameters and incidence of ILI and pertussis. Among the variables, pertussis and PM₂.₅ may have the strongest association, albeit p>0.05. Other factors contributing to the increase of disease counts may be explored including vaccine rates and case reporting. Conclusion There is insufficient evidence to show that fire events and higher PM₂.₅ levels at a regional scale increased the risk for ILI and pertussis in 2017-2018. Further studies may be explored on how satellite-derived atmospheric data can be utilized in respiratory health studies.
Whooping Cough

Species were applied by the Centre for the vaccine quality control including Bordetella pertussis GL 353 type 1; Bordetella pertussis 360 E type1, 2; Bordetella pertussis H36 type 1, 3. The methods: preparation of the medium Bordet- Gengou; production of the serum fast according to the methods of the surface culture in Bordet-Gengo medium in bottle of Roux; immunization and collection of serum fast; absorption of the non- specific antibody. The results have shown that the antibody effect of type 1, type 1, 2 and type 3, 4 in the 14th day after the 6 injection of the outlines immuned higher than this in the seventh day. The combination of pertussis antigen with Aluminum phosphate increases immunoability in all three types with some effects. Therefore, a monovalent pertussis serum fast has made in the allowed standard. The ability of agglutination and specificity of the produced pertussis serum fast were the same as these of the England National Institute of vaccine and biological substances
vaccines ; Whooping Cough

Using 0.1% formalin for inactivation and detoxification in the production of pertussis vaccine gave good results with 3 experimental lots PM10, PM11, and PM12 had high safety: MWG test was 76%-84.2% higher than control lots 62.4%, LPF test was 32,210-41,200 lower than control lot 58,600. The preliminary findings suggest these 3 experimental lots had less toxicity than standard and control lot. This method can be used in routine pertussis vaccine production
Pertussis Vaccine ; vaccines ; Whooping Cough

The Institute of Vaccine had elaborated a procedure of preapration and produced successfully a 4 component liquid vaccine of diphteria – tetanos – coqueluche and meningitis (DTP-Hib). The quality have reached the standards issued in European and WHO Pharmacopoeia. The procedure of preparation of DPT-Hib mixt vaccine and the preliminary procedure of its quality control were established
Vaccines ; Diphtheria ; Tetanus ; Whooping Cough

After 3 months storage at 4oC and 4 weeks storage at room temperature, 3 lots of monospecific pertussis antiserum of type 1, type 2, type 3 produced in Da Lat Vaccine Institute were still met the requirement of specificity and sensitivity. But they were degraded after 5 weeks of storage at room temperature (24-26oC)
Whooping Cough ; Pertussis Vaccine ; immunization

No abstract available.
Adult* ; Cough* ; Diagnosis, Differential* ; Humans ; Whooping Cough*

No abstract available.
Adult* ; Cough* ; Diagnosis, Differential* ; Humans ; Whooping Cough*

No abstract available.
Animals ; Pertussis Vaccine* ; Rats* ; Streptozocin* ; Whooping Cough*

17 final bulks of pertussis suspension, combined with AlPO4 were evaluated for specific toxicity by MWG test, LPF test and MICRO LAL test. Results showed that: there was relationship between potency and specific toxicity of the vaccine. LPF test was found more reliable than MICRO LAL test when compared to MWG test.
Diphtheria-Tetanus-Pertussis Vaccine ; Whooping Cough ; toxicity

The pertussis surveillance system has been established since 2009 in Tianjin, and continuously improved over the past 10 years. This system determines the definition and classification of pertussis, establishes simple and feasible sampling methods and laboratory detection methods in clinical practice, standardizes the report management of pertussis cases and the treatment of epidemic situations. After the implementation of the surveillance system, the number of reported pertussis cases increased from 26 in 2009 to 802 in 2017, the number of diagnosed cases increased from 19 in 2009 to 662 in 2017, the reported incidence rate of pertussis increased from 0.16/100 000 in 2009 to 4.28/100 000 in 2017, and the number of medical institutions of reporting perutssis cases increased from 2 in 2009 to 53 in 2017. The specimen collection rate of the reported cases reached up to 93.66%. These results show that the sensitivity of pertussis surveillance has been improved and show that the data from the surveillance system may reflect more precisely the epidemical characteristics of perutssis in Tianjin.
Humans ; Incidence ; Infant ; Pertussis Vaccine ; Whooping Cough