Objectve To study the techniques and clinical effect of transurethral holmium laser enucleation of the prostate (HoEAP) and prostatic tissue morcellation. Methods 61 patients of benign prostate hyperplasia(BPH) were operated on HoEAP with high power 100 w holmium laser and prostatic tissue morcellation with tissue morcellator. Results All the patients successed.The operation time of resected prostate was (25～68) min The tissue weight of resected prostate was (25～66)gm.The morcellation time of tissue was (20～90) min.All the patients got normal micturition after urethral indwelling catheter(16～96) hours.All patients had been followed up for 2 months to 8 months with a mean ot 5 months.Acording to Symptemic Scores.(I-PSS),the results of therapy were assessed as follows:excellent in 54(65.8%),good in 16 (19.5%),moderate in 12(14.6%). Conclusion The techniqne of HoEAP and prostate tissue morcellation can provide accurate,safe and faster cutting with less blood loss.A reliabe tissue morcellation and shorten operation time remarkebly are obtained.Postoperation results show a prompt unobstructed,effect.