1.Evaluation and improvement of anti-interference performance of D-3-hydroxybutyrate detection reagent
Jie WANG ; Wenxue JIAO ; Guichun ZHANG
International Journal of Laboratory Medicine 2014;(15):1991-1992
Objective To evaluate the anti-interference performance of D-3-hydroxybutyrate (D3H ) reagent kit by using the NCCLS document EP7-A2 and to improve its anti-interference performance .Methods The anti-interference evaluation test of D3H kit was performed according to NCCLS document EP7-A2 and its anti-interference performance was improved by adding vitamin C oxidase .Results 342 mol/L free bilirubin ,342 mol/L conjugated bilirubin ,1 450 FTU chyle and 5 g/L hematoglobin had no inter-ference on the high concentration D3H detection ,0 .03 g/L vitamin C interfered with the low and high concentration D3H detection . The dosage-effect experiment results showed that vitamin C produced the linear positive interference effect on D 3H detection . Adding 2 500 U/L of vitamin C oxidase could antagonize the interference of vitamin C on detection .Conclusion Vitamin C can in-terfere with the D3H detection and adding vitamin C oxidase in reagent can antagonize its interference .
2.Risk factors for early death in patients with cervical spinal cord injury
Xinxu JIAO ; Shiqing FENG ; Tieqiang DING ; Jingwei LI ; Xueli ZHANG ; Shucai DENG ; Wenxue JIANG ; Jinggui WANG
Chinese Journal of Trauma 2011;27(5):423-427
Objective To explore the causes and risk factors affecting early death in patients with traumatic cervical spinal cord injury (SCI). Methods Clinical data of 553 patients with traumatic cervical SCI were analyzed retrospectively to discuss the related factors affecting early death of patients with traumatic cervical SCI by using univariate analysis and multivariate logistic regression analysis. Results The early mortality of the patients with traumatic cervical SCI was 4.0% ( 22/553 ). The main causes of the early death were respiratory failure in nine patients (40.9%) and electrolyte disorders in five (22.7%). Univariate analysis showed that age, cervical spinal cord injury severity, complications in respiratory, cardiovascular, digestive systems and electrolyte disturbance as well as tracheotomy were considered statistically significant for early death in patients with traumatic cervical SCI ( P < 0, 05 ). Multivariate logistic regression analysis showed that age, cervical SCI severity, complications in respiratory,cardiovascular system and electrolyte disturbance as well as tracheotomy. Conclusion Severe cervical SCI, combined respiratory, cardiovascular system and electrolyte disorder complications as well as tracheotomy are high risk factors for the early death in patients with traumatic cervical SCI.
3.A Survey of the Current Status of Surgical Treatment of Hemophilic Osteoarthropathy in China Mainland 17 Grade A General Hospitals
Yiming XU ; Huiming PENG ; Shuaijie LYU ; Peijian TONG ; Hu LI ; Fenyong CHEN ; Haibin WANG ; Qi YANG ; Bin CHEN ; Zhen YUAN ; Rongxiu BI ; Jianmin FENG ; Wenxue JIANG ; Zongke ZHOU ; Meng FAN ; Xiang LI ; Guanghua LEI ; Xisheng WENG
JOURNAL OF RARE DISEASES 2023;2(4):516-522