Objective To evaluate the value of health intervention to changeable risk factors in persons with diabetes prophase.Methods One hundred and eighteen persons in diabetes prophase were divided into two groups randomly.For 58 persons enrolled in the experimental group,health intervention including lectures of diabetes basic knowledge,introducing the necessity and significance of periodical check up and examination,suitable dietary and nutrition,weight control,physical exercise and movement was performed.For 60 persons enrolled in the control group,only the diagnosis of diabetes prophase was informed.The incidence of normalization of blood glucose and progressing to dominant diabetes was compared between the experimental group and the control group after follow-up for 6 months and 12 months.Results After 6 months of intervention,the difference of the number of persons was not significant for normalization of blood glucose between experimental group and control group(x2=0.04 and 0.79,P=0.84 and 0.12 for persons with IFG and IGT respectively),and was also not significant for progressing to dominant diabetes between the two groups(x2=0.96,P=0.33).After 12 months of intervention,the difference of the number of persons was significant for normalization of blood glucose between experimental group and control group(x2=13.34 and 22.58,P<0.01 and<0.01 for persons with IFG and IGT respectively),but still not significant for progressing to dominant diabetes between the two groups(x2=2.83,P=0.09).Conclusions The intervention to changeable risk factors can prevent or delay the occurrence of diabetes mellitus,and improve the quality of life for person with diabetes prophase.

Objective To evaluate food intolerance sensitivity among 2962 health check-up receivers from the First Hospital of China Medical University.Methods Serum samples of 2962 adults were collected from January 2008 to June 2010.Serum allergen-specific IgG antibodies of 14 kinds of food were detected by ELISA.The data were analyzed by using One-way analysis of variance.Results In this study,the rate of food intolerance was 0.4%(mushrooms) to 38.0%(eggs).Higher rates of food intolerance were found in egg,crab,shrimp,milk,and cod fish(Eggs 32.5%,crabs 26.0%,shrimps 19.8%,milk 13.8%,and cod fish 12.0% respectively).However,wheat,pork,and mushroom showed relatively lower rates of food intolerance(Wheat 0.8%,pork 0.4%,and mushrooms1.4% respectively).Positive reaction to food intolerance was even stronger in women(9.4% versus 8.2%).Conclusion It is discovered by study that in general population,the diversity of intolerance among different food is associated with 4 factors: gender; age; feature of food; individual diversity.It is recommended that the status of intolerance to food in the general population be investigated by health management.

ObjectiveTo explore the relationship among 14 kinds of intolerant food by using association rules to provide evidence for more reasonable diet intake.Methods A total of 2962 adults who received medical examination at the First Affiliated Hospital of China Medical University during January 2008 and June 2010 were enrolled in this investigation.ELISA was used to detect allergen-specific IgG antibody of 14 kinds of food.An association rules model was established by SPSS Clementinel2.0.In order to find positive intolerance association rules,food frequency was recorded with SPSS 16.0.Results Five most commonly seen food intolerance were eggs,crabs,shrimp,milk,and cod (positive rates were 32.5％,26.0％,19.8％,13.8％ and 12.0％,respectively).Positive association rules were found in crab and shrimp,or milk and eggs.Single order association was found in female,while multi-order association was identified in male.Conclusions Our data show a strong positive association among animal foods.Female may be affected by milk,eggs and seafood,while male may be affected by a variety of foods.