Extracorporeal membrane oxygenation (ECMO) is an extracoreal life support technique,which is used as a method of cardiopulmonary replacement therapy for patients who had cardiopulmonary nonfiction.ECMO may obtain precious time for evaluation,diagnosis,treatment and restitution of dangerous diseases.This paper introduced the research progression of ECMO on relative knowledge,clinical application in pediatrics,complication and its prevention and cure in applied process.This review on ECMO will deepen understanding and widen the vision on clinical application of ECMO in pediatrics further.

As a member of homeobox gene family,HOXA7 is a main gene to control hematopoietie cell proliferation and differentiation.The expression and function of HOXA7 in leukemia ale regulated by many upstream elements.and affected by synergism molecules and other homeobox genes. It can induce leukemia through acting on downstream target genes.HOXA7 affects the clinical manifestation of leukemia and overexpression is closely associated with poor therapeutic reaction and prognosis.

Objective:To elucidate the effect of osteogenic growth peptide (OGP) on proliferation and differentiation of human periodontal ligament cells on titanium disc in vitro. Methods:Human periodontal ligament cells were cultured located on titanium disc individually in medium contained various concentrations of OGP;and cell proliferation quantity were examined by MTT and alkaline phosphatase activity were examined by enzyme-linked immunosorbentassay. Results:In vitro,the addition of OGP in cultures resulted in an increase of cell proliferation and ALP activity(P

Essential thrombocythemia (ET) which is a clonal disease of hematopoietic stem cell mainly reflects hyperplasia of megakaryocyte. Childhood ET is characterized by persistance of thrombocytosis, mild to moderate hepatomegalia and splenomegalia, thrombogenesis and hemorrhage complications. The pathogenesis of ET is obviously associated with the abnormal or disturbance expression of multiple genes, micro RNAs,immunological molecules and some chromosome aberration. This review will focus on recent developments in the pathogenesis of ET in molecular biology, immunology and cytogenetics.

Objective To explore the role of mental health between nursing interns' professional commitment and occupational choice self-efficacy.Methods 200 students were surveyed by Career Decisionmaking Self-efficacy Scale,the Symptom Self-rating Scale(SCL-90) and Professional Commitment Scale for Undergraduates.Results Professional commitment showed remarkable positive prediction effect.Mental health exhibits moderating effect on the relationship between professional commitment and occupational choice self-efficacy,the more good mental health level,the bigger the prediction effect of professional commitment on occupational choice self-efficacy.Conclusions Promoting the students' psychological health will improve prediction effect of professional commitment on occupational choice self-efficacy.

ICU is the important place of ventilator associated pneumonia, the occurrence of fatality rate in patients with ventilator associated pneumonia is higher. In this paper, the cause of the ventilator associated pneumonia in ICU and nursing research progress are summarized, that enhance their awareness of the importance of nursing care and the use of normative evidence-based nursing in clinical practice thinking and nursing process, explore the nursing methods of more appropriate, to reduce the incidence of ventilator associated pneumonia in ICU is of great help.

Capsular polysaccharides(CPSs) are located on the surface of Gram-negative bacterial cells and form a vesicular structure covering the surface, which are receptors for bacteriophages to adsorb host bacteria and determine their lytic activity and host range. The quorum sensing gene luxR inhibits phage adsorption by regulating reduced CPS expression,making Gram-negative bacteria tolerant to phages. LuxR quorum sensing system is a kind of intercellular communication system widely existing in Gram-negative bacteria, which is responsible for synthesizing self-inducers, sensing and responding to N-acyl-homoserine lactones(AHLs) signals, and can regulate biofilm formation, control the production of virulence factors,coordinate group behavior and mediate bacteria-environment interaction, playing a key role in the regulation of bacterial group behavior. This paper reviews the research progress on molecular mechanism of CPS-mediated phage tolerance regulated by LuxR quorum sensing system in Gram-negative bacteria, aiming to provide new ideas for phage therapy for bacterial infection.

With the development of capsule endoscopy, developing active capsule endoscopy robot becomes a growing trend. Although stomach diagnosis with robot has been put into clinical test, the realization of the complete intestinal capsule endoscopy is still a difficulty. This paper reports the status quo of the research process for intestinal capsule endoscopy robot, and analyzes their advantages, defects and prospects for development, which provides reference for the research of intestinal capsule endoscopy robot.
Capsule Endoscopy ; instrumentation ; Humans ; Intestines ; Robotics ; trends

Adult ; Female ; Health Status ; Humans ; Male ; Middle Aged ; Occupational Exposure ; prevention & control ; Physical Examination ; Physicians ; Radiation Injuries ; prevention & control

Objective To investigate MRI features of dysembryoplastic neuroepithelial tumor(DNT).Methods The MR images of ten cases with surgically and pathologically proved DNT were retrospectively reviewed.Results MR imaging showed cystic component with mural nodule in 6,mainly cystic component with septa in 3.The solid components of the tumors were long T_1 and long T_2 signal intensity,the cystic components were even longer T_1 and T_2 signal intensity which resembled the signal of cerebrospinal fluid.Mild enhancement could be found at the intra-tumoral solid nodule or septations after injection of constrast medium but the cystic component did not show any enhancement.No peri-tumoral edema and mass effect were found in most cases.Conclusion DNTs are of some special features on the MR images,the diagnosis can be exactly done before operation if MRI features in combination with clinical data of the patients.