Objective To observe the changes of serum adiponectin and free fatty acids in different glycometabolic states and to ex- plore their roles in the development and progression of diabetes. Methods The serum adiponectin and free fatty acids in 25 subjects with normal glucose (NGT) ,27 subjects with impaired glucose tolerance (IGT) and 25 subjects with diabetes (T2DM) , and the effects of these factors on insulin resistance (HOMA - IR) and islet ficell function(HBCI) were analyzed respectively. Results (1) Serum levels of adiponectin was lower in T2DM and IGT as compared with NGT and the level of FFA was increased in T2DM and IGT compared with NGT and the differences were significance (P

Objective: To review the influence of various processing methods on the content of baicalin in radix Scutellariae and its preparations. Method: The content of baicalin was determined by HPLC. Results: The content of baicalin decreased evidently when the brocessing method was in appropriate. Conclusion: Improper processing method can decrease the content of baicalin, and frying and carbonizing destroyed baicalin seriously.

Objective:To evaluate the safety of one-lung ventilation and artificial hydrothorax to aid HIFU treatment of liver carcinoma located in distal end of diaphragm and edge of liver and to observe the related indices in the treatment.Methods:Twelve patients with liver carcinoma received general anesthesia using double lumen endobronchial tube bi-chamber trachea cannula.Saline was injected into right thoracic cavity to turn artificial pleural fluid.During HIFU treatment,left lung had a ventilation with 100% FiO_2.Before cannula(value of Base);one lung was ventilated(DLV) for 15 mins,30 mins,60mins,120mins,then double lungs received ventilation again for 30mins(DLV'30).And blood gas was analyzed separately.Vital monitoring machine kept observing ECG,HR,MAP,S_pO_2,and PETCO2.One day and seven days after HIFU,X-ray was made to evaluate the outcome of hydrothorax.Results:All the patients were steady in blood gas and hemodynamic indices at the period of one-lung ventilation with artificial hydrothorax.The indices of PO_2 were higher during one-or two-lung ventilation than Base (P

AIM:To develop a RP-HPLC method for simultaneously determining three major compounds in Qingre Mingmu Tea(Semen Cassiae,Flos crysanthemi,etc),namely emodin,chrysophanol and physcion with UV detection wavelength at 254 nm. METHODS: The column was Diamonsil C_(18)(250 mm?4.6 mm i.d,5 ?m).The separation was carried out with a gradient program.The mobile phase was acetonitrile-0.1% phosphoric acid at a flow rate of 1.0 mL/min. RESULTS: The standard curve was rectilinear in the range of 5.335213.4 ng(r=(0.999 8)) for emodin,9.075-363.0 ng(r=0.999 8) for chrysophanol,and 4.688-187.5 ng(r=1.000 0) for physcion,respectively.The recoveries of the markers listed above were 96.0%,106.5% and 98.1%,respectively. CONCLUSION: The method is simple,rapid and suitable for the determination of three compounds in Qingre(Mingmu) Tea.

Crohn's disease (CD) complications include intestinal complications,parenteral complications,and systemic manifestations,of which intestinal complications are the most common.These complications result in serious damage to the quality of life,the risk of life-threatening may also appear.How to deal with these complications has become a major challenge for clinicians.CD requires a multidisciplinary treatment team,treatment complications versa.This review summarized the treatments of CDcommon complications.

Student leaders are the important work force which the college student management and education in the process to rely on.They are not only the bridge and link between schools,teachers and ordinary students,but also the reserve of schools and social management cadres.Grasping and analyzing their basic conditions,the growing demand and group identity is significant.In this paper,the group identity of the student leaders has been sorted out,and their needs and deficiencies are understood through research and discussion about their positioning in the self-awareness,growth and success.And by drawing on the experience of student affairs management in the United States such as ＂student services＂,＂student development ＂,＂student learning＂,we put forward some suggestions in team-building and personnel training of the current student leaders etc..

ObjectiveTo investigate the risk of cerebral infarction on pat ients with transient ischemicattack (TIA) by combining ABCD2 score and three imaging methods.MethodsFive hundred and seventy-eight patients with TIA visiting our hospital from January 2007 to December 2011 were assessed for the risk of cerebral infarction after TIA by ABCD2 score method,magnetic resonance diffusion weighted imaging (DWI),magnetic resonance angiography (MRA) and carotid artery color Doppler imaging (CDFI).Cases were followed up on 2 d,7 d and 30 d for incidence of cerebral infarction.ResultsCerebral infarction occurred in 37 cases (6.40％),47 cases ( 8.13％ ) and 61 cases ( 10.55％ ) on day 2,day 7 and day 30.The occurrence of cerebral infarction after TIA in high risk group (35 cases ) by single ABCD2 score was found in 15 cases (42.86％ ),18 cases (51.43％) and 21 cases (60.00％) on day 2,day 7 and day 30.Twenty-eight cases (54.90％),31cases (60.78％ ),and 38 cases (74.51％ ) of patients after TIA with ABCD2 ＞ 3 and DWI positivity (51cases) suffered cerebral infarction on day 2,day 7 and day 30.Cerebral infarction occurred in 22 cases (61.11％),24 cases (66.67％ ) and 30 cases (83.33％) of patients with ABCD2 ＞ 3 points and cerebral artery stenosis (36 cases) on day 2,day 7 and day 30 after TIA.The occurrence of cerebral infarction after TIA on day 2,day 7 and day 30 were in 21 cases ( 60.00％ ),23 cases ( 65.71％ ),28 cases ( 80.00％ ) of the patients with ABCD2 ＞ 3 points and the carotid artery atheroma-caused bureaucratic stenosis (35 cases).There were no significant difference in the value of three methods to assess the risk of cerebral infarction in high-risk TIA groups (P ＞ 0.05).ConclusionTIA patients can progress to cerebral infarction in the short term.There are some predictive value by ABCD2 score from 2 to 30 days for cerebral infarction occurring after TIA,but it is only a simple clinical assessment method.ABCD2 score ＞ 3 points must be combined with DWI,MRA,and other tests in high-risk patients to identify the risk of cerebral infarction,thus improving the accuracy of the prediction.The combined evaluation of TIA patients will help the clinicians give better treatment and decision to this group of patients

Objective To investigate the timing and security of oral glucose tolerance test (OGTT) in patients with acute coronary syndrome (ACS).Methods Two hundred and thirty-two hospitalized patients with ACS were collected from Jan.2007 to Jan.2012.OGTT was undergone in a stable condition at 3 months after being discharged,noting ECG and change of symptoms in patients.Results There was no significant difference in test results of proportions of patients with normal blood sugar [40.95％ (95/232) vs.39.91％ (89/215),x2 =0.051,P ＞ 0.05 ],diabetes [ 25.00％ (58/232) vs.22.33％ (48/215),x2 =0.032,P ＞ 0.05 ],impaired glucose tolerance [ 34.05％ (79/232) vs.33.95％ ( 73/215 ),x2 =0.001,P ＞ 0.05 ],and impaired fasting glucose [2.59％ (6/232) vs.2.33％ (5/215),x2 =0.441,P ＞0.05 ] at 3 months after discharge compared with before discharge when patients were in stable conditions.No significant difference was found on ST segment ECG [ (-0.12 ±0.08 ) mV vs.(-0.15 ± 0.12) mV,t =0.23,P =0.85].Adverse symptoms were not found during the OGTT examination.Conclusion Patients with ACS have a high risk of abnormal glucose metabolism.Undergoing OGTT is safe for stable status patients with ACS.OGTT should be conducted as the routine exam.Early detection and appropriate intervention and treatment are necessary for patients with abnormal glucose metabolism.

OBJECTIVE： To prepare pefloxacin mesylate eye drops.METHODS： The content of pefloxacin was determined with UV－ spectrophotometry.The therapeutic effect of the eye drops was observed in 170 out－ patients.RESULTS： The linearity range was 2～ 14μ g/ml with a regression equation of A=0.1 018C and r=0.9 999(n=7).The average recovery was 99.64％ with a RSD of 0.43％ .After treatment,150 out－ patients recovered,16 out－ patients improved and 4 out－ patients had no efficiency with a total effective rate of 97.6％ .CONCLUSION： The eye drops has definite therapeutic effect.The UV－ spectrophotometry method is simple,rapid and accurate in determination of the content and no special reagent is needed.