0.05) at the latest follow up. All the cases achieved solid fusion within 12 months. Nineteen cases with incomplete paraplegia obtained an average improvement of 1.26 grades by Frankel neurological classification. The major complications in this group included one case with temporary deterioration of neurological function. Another case with pulmonary atelectasis on the operation side, but cured with appropriate treatment. Conclusion One stage surgical treatment for multiple-level tuberculosis of the upper thoracic spine by combined anterior and posterior spine fusion with posterior instrumentation is feasible and effective without major complications. Early surgical intervention should be emphasized for the treatment of progressive tuberculosis of the upper thoracic spine.