1.The clinical characteristic and misdiagnosis of blephaokeratoconjunctivitis
Chinese Journal of Primary Medicine and Pharmacy 2017;24(3):378-381
Objective To explore the clinical symptoms,signs,and analysis of misdiagnosis of blephaokera-toconjunctivitis(BKC).Methods The clinical data of 88 patients with BKC in our hospital from June 2014 to June 2016 were retrospectively analyzed.Based on the patients'symptoms,signs and BKC diagnostic criteria,the causes of misdiagnosis were analyzed.Results In 88 patients with BKC,59 cases were misdiagnosed,the misdiagnosis rate was 67.04%.The People's Hospital of Anshun misdiagnosed 10 cases(12.19%),among which resident misdiagnosed 6 cases(6.81%),attending physician misdiagnosed 2 cases (2.27%),deputy director and the above physician misdiagnosed 1 case (1.13%);outer court misdiagnosed 49 cases (55.68%),among which three level hospital misdiagnosed 8 cases(9.09%),II level hospital misdiagnosed 23 cases(26.13%),a level hospital and the following misdiagnosed 18 cases (20.45%);misdiagnosis disease including virus sex keratitis 14 cases(15.9%),chronic blepharitis in 13 cases(14.77%),the meibomian gland dysfunction(MGD)in 10 cases(11.36%),8 cases of dry eye(9.09%),6 cases of chronic conjunctivitis(6.81%),allergic conjunctivitis 5 cases (5.68%),marginal corneal ulcer in 3 cases(3.4%).Conclusion The clinical characteristics of BKC and viral keratitis,chronic blepharitis, MDGS and dry eye disease are similar and overlap,and clinicians are lack of knowledge and awareness of the disease, the clinical misdiagnosis and mistreatment is vulnerable,especially in primary care doctors.We should pay attention to the clinical patients'history,symptoms,slit lamp microscope examination of palpebral and conjunctival and corneal conditions,etc.thus to reduce misdiagnosis and avoid medical disputes.
2.Case of Brucellosis.
Wenlong YANG ; Fangming LIU ; Zhongshu ZHU
Chinese Acupuncture & Moxibustion 2015;35(10):1044-1044
Acupuncture Therapy
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Adult
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Brucellosis
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therapy
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Humans
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Male
3.Clinical application of diffusion tensor imaging in acute stroke
Jing ZHAO ; Wenlong CHANG ; Yonggang LIU
Clinical Medicine of China 2014;30(11):1166-1168
Objective To reveal the transmiting discipline of parameters and define therapy time window of ischemia penumbra by continuous detection of diffusion tensor imaging(DTI) o Methods 35 patients with acute cerebral infarction in different phases were imaged with conventional DWI and DTI.To measure DCavg,FA,RA,1-VR,ADC in different regions of interest (ROI).Results Change in DCavg had tendency which appear reduced obviously,elevated,renormalized,increased.FA/RA/1-VR of lesions elevated in hyperacute stroke and unrecovered declined acute to sub-acute stroke.Difference of DCavg,FA,RA,1-VR between central and periphral parts of lesions were significant in hyperacute and acute stroke.ADC of lesions were significant in hyperacute and acute stroke.Difference of FA between central and peripheral parts of lesions were significant in acute stroke(P < 0.01).Difference of ADC,DCavg between central and peripheral parts of lesions were significant in acute and subacute stroke(P < 0.01).Conclusion It had characteristic discipline in changes of DCavg,FA,RA,1-VR,ADC,The peripheral parts of lesions in hyperacute and acute stroke maybe ischemia penumbra,DTI has important practical value for clinical.
5.Fingerprint of volatile in Ganlu Xiaodu Granules
Wenlong LIU ; Fuyuan HE ; Xili ZHANG
Chinese Traditional Patent Medicine 1992;0(08):-
AIM: To study the volatile oil of GanluXiaodu Granules GLXD (Talcum, Herba Artemisiae Scopariae, Radix Scutellariae etc.) and establish it's fingerprint. METHODS: By capillary gas chromatography. RESULTS: The fingerprints of volatile oil in Ganlu Xiaodu Granules were composed of 56 peaks, among which there were 17 characteristic peaks, having 86.97% of total area of the whole fingerprints peaks. The average RSD of retention time of characteristic peaks was 0.33%, that of peak-area was 2.76%. CONCLUSION: The fingerprints of volatile in Ganlu Xiaodu Granules can be used to control the quality.
6.Discussion on strengthening the clinical departments of compulsive calibrating equipment works
Wenlong ZHAO ; Yuan LIU ; Peng GAO
China Medical Equipment 2013;(11):96-97,98
Objective:To improve our hospital staff on medical safety awareness. To strengthen the medical device safety management practices. Methods:On the status of hospital, improve the scientific management level of medical equipment. On clinical equipment compulsory verification process, strong check of equipment maintenance is discussed. Results:the clinical departments to further understand the importance of safety in medical equipment using. Conclusion:Enhancement of medical engineering professional cooperation, improve the inspection equipment safety, reliability and validity.
7.Risk factors for poor prognosis of severe adenovirus pneumonia in children
Zhenzhen WANG ; Wenlong FU ; Helin LIU
Chinese Journal of Infection Control 2016;15(8):587-591
Objective To understand the risk factors for poor prognosis of severe adenovirus pneumonia (SAP)in children,and provide guidance for clinical diagnosis and prognosis.Methods Clinical data of 91 hospitalized children who diagnosed with SAP in Chongqing Children’s Hospital of Chongqing Medical University between January 2012 and January 2014 were analyzed retrospectively.Results Of 91 SAP children,23 (25.27%)had poor prognosis. Univariate analysis showed that risk factors for poor prognosis of SAP were age of onset,congenital heart disease and other serious underlying diseases,mechanical ventilation therapy,acute respiratory distress syndrome (ARDS), atelectasis and other serious radiological changes,and emergence of two and more extra-pulmonary complications (all P <0.05).Multivariate regression analysis showed that congenital heart disease and other serious underlying diseases,and emergence of two and more extra-pulmonary complications were independent risk factors for poor prognosis of SAP (all P <0.05).Conclusion Congenital heart disease and other serious underlying diseases,emer-gence of two and more extra-pulmonary complications are independent risk factors for poor prognosis of SAP,active intervention should be conducted during the process of clinical diagnosis and treatment,so as to improve the prognosis.
8.Diagnosis and treatment of adrenal tumors:a review of 1006 cases
Dingyi LIU ; Yuxuan WU ; Wenlong ZHOU
Chinese Journal of Urology 1994;0(02):-
Objective To study the diagnosis and treatment of adrenal tumors. Methods 1 006 cases of adrenal tumors treated from 1957 to 2000 were reviewed. Results Of the 1 006 cases of adrenal tumors,845(84.0%) were functional with 12(1.4%) malignant and 161(16%) nonfunctional with 11( 6.8%) malignant.There were 180 incidentaloma including 19 pheochromocytoma.A total of 996 tumors have been surgically removed and 10 cases underwent surgical exploration only.The total mortality rate was 0.3%. Conclusions Adrenal tumors occurred mostly in patients of 30~50 years of age.The prevalence of Cushing syndrome was more in females than in males.Ultrasonography and CT are the method of choice for the localization of the tumor whereas hormone levels should be determined both in the symtomatic and asymtomatic patients with adrenal tumors.Functional adrenal tumors and solid incidentaloma of large size should be surgically removed while asymtomatic incidentaloma less than 3 cm in size could be observed and followed up and surgery might be undertaken when indicated.
9.The evalution of imaging diagnosis of adrenal tumors (report of 385 cases)
Fukang SUN ; Wenlong ZHOU ; Dingyi LIU
Chinese Journal of Urology 2001;0(04):-
Objective To elevate ability of diagnosing adrenal tumors. Methods B-ultrasonography were performed on 385 cases;CT scanning were on 385 cases;IVU were on 380 cases;MRI were on 180 cases;Doppler were on 63 cases;DSA were on 16 cases;MRA were on 28 cases;MIBG were on 34 cases;3 cases were performed tumors biopsy directed through CT. Results The accurate localization rate of APA,Cushing tumors,Pheo,myelolipoma with B-ultrasonography were 92.7%,88.3%,100.0%,100.0% respectively.The accurate qualitative rate of diagnosis were 83.2%,86.7%,83.4%,100.0% respectively.With CT scanning were 98.2%,98.7%,100.0%,100.0% and 90.5%,92.3%,83.4%,100.0% respectively.With MRI were 90.4%,96.5%,100.0%,100.0% and 72.8%?93.5%?85.8%?100.0% respectively. Conclusions The overall data of imaging is helpful in diagnosis of adrenal tumors.Correct localization of the tumors is the key step for the treatment.
10.Establishment of the mathematic model of total quantum statistical moment standard similarity for application to medical theoretical research.
Fuyuan HE ; Kaiwen DENG ; Sheng HUANG ; Wenlong LIU ; Jilian SHI
Acta Pharmaceutica Sinica 2013;48(9):1453-8
The paper aims to elucidate and establish a new mathematic model: the total quantum statistical moment standard similarity (TQSMSS) on the base of the original total quantum statistical moment model and to illustrate the application of the model to medical theoretical research. The model was established combined with the statistical moment principle and the normal distribution probability density function properties, then validated and illustrated by the pharmacokinetics of three ingredients in Buyanghuanwu decoction and of three data analytical method for them, and by analysis of chromatographic fingerprint for various extracts with different solubility parameter solvents dissolving the Buyanghanwu-decoction extract. The established model consists of four mainly parameters: (1) total quantum statistical moment similarity as ST, an overlapped area by two normal distribution probability density curves in conversion of the two TQSM parameters; (2) total variability as DT, a confidence limit of standard normal accumulation probability which is equal to the absolute difference value between the two normal accumulation probabilities within integration of their curve nodical; (3) total variable probability as 1-Ss, standard normal distribution probability within interval of D(T); (4) total variable probability (1-beta)alpha and (5) stable confident probability beta(1-alpha): the correct probability to make positive and negative conclusions under confident coefficient alpha. With the model, we had analyzed the TQSMS similarities of pharmacokinetics of three ingredients in Buyanghuanwu decoction and of three data analytical methods for them were at range of 0.3852-0.9875 that illuminated different pharmacokinetic behaviors of each other; and the TQSMS similarities (ST) of chromatographic fingerprint for various extracts with different solubility parameter solvents dissolving Buyanghuanwu-decoction-extract were at range of 0.6842-0.999 2 that showed different constituents with various solvent extracts. The TQSMSS can characterize the sample similarity, by which we can quantitate the correct probability with the test of power under to make positive and negative conclusions no matter the samples come from same population under confident coefficient a or not, by which we can realize an analysis at both macroscopic and microcosmic levels, as an important similar analytical method for medical theoretical research.