2.Clinical effect evaluation of 131 I for treating elderly hyperthyroid heart disease
Wenjun ZHANG ; Lichun ZHENG ; Xiaoming ZHANG
Chongqing Medicine 2013;(25):2959-2960,2963
Objective To evaluate the clinical value of 131 I in the treatment of senile hyperthyroid heart disease .Methods 95 ca-ses of elderly hyperthyroid heart disease were orally treated by 131 I .The thyroid function was detected before 131 I therapy and in 3 months ,6 months and 1 year after treatment .The gated blood pool imaging was performed before treatment and in 1 year after treatment for evaluating the therapeutic effect .Results The cure rate was 97 .89% for hyperthyroidism ,100 .00% for paroxysmal atrial fibrillation and 84 .00% for persistent atrial fibrillation .FT3 ,FT4 and TSH levels had statistical difference between before treatment and in 3 ,6 ,12 months after treatment (P<0 .05) .The left ventricular systolic and diastolic function parameters had sta-tistical differences between before treatment and in 1 year after treatment (P< 0 .05) .The left ventricular systolic and diastolic function was improved significantly .Conclusion Selecting radioactive 131 I for treating elderly hyperthyroid heart disease is the key to improve hyperthyroid heart disease ,can effectively control the FT3 ,FT4 and TSH levels and improve the heart function .
3.Detection of myocardial coronary flow reserve of syndrome X by real-time myocardial contrast echocardiography
Wenjun ZHANG ; Shaowen GUO ; Yi HE
Chinese Journal of Ultrasonography 2009;18(4):308-310
Objective To evaluate myocardial coronary flow reserve of syndrom X by real-time myocardial contrast echocardiography(MCE). Methods Ten patients with syndrome X and seven normal subjects were involved in the study. Real-time MCE was performed with acoustic contrast SonoVue,and the peak video density (A), and re-turgor velocity of microvessel (β), and the product of A ×β of quiescent condition and after adenosin loading were detected,and also the coronary flow reserve (CFR, the ratio of A xβ circa-adenosin loading). Results There was no significant difference of A between syndrom X and contrast group in quiescent condition, the β and product of A x β of patients with syndrome X were lower than those of contrast group, the CFR of syndrome X was obviously less than that of contrast group.Conclusions Myocardial microvessel function is abnormal in syndrome X, real-time MCE is useful for evaluate myocardial coronary flow reserve.
4.Treatment of SIRT for unresectable hepatic metastasis from colorectal cancer
Fangjuan HU ; Wenjun ZHANG ; Changlin ZHAO
Journal of International Oncology 2011;38(9):703-707
Colorectal cancer is the third high incidence of tumor in the world,and liver is one of the most common sites of distant metastasis.Liver metastasis accounts for 50%-75% in distant metastasis.Only about 10% -15% of patients are candidates for resection,and the recurrence is easy.Selective internal radiation therapy is a new type of radiotherapy.It is partial and liver-targeted.For unresectable colorectal liver metastasis,selective internal radiation therapy alone or in combination with other therapies can reduce cancer focus,prolong the survival,and maybe improve overall survival.
5.Investigation in climacteric symptoms and depression of gynaecology outpatients and inpatients
Yuanyuan ZHANG ; Caifeng ZHOU ; Wenjun FU
Chinese Journal of Practical Nursing 2011;(31):62-64
Objective To investigate the climacteric symptoms and depressive related factors of climacteric females in gynecology outpatients and inpatients,to provide evidence for effective health promotion.Methods 416 climacteric women were investigated by using improved menopause Kuppermen Scales and Center for Epidemiological Studies Depression (CES-D).The results underwent analysis.Results There were 93.99% of patients suffering from climacteric syndrome,49.52% with depression symptom.The main factors of climacteric syndrome were eating breakfast according to the timetable every day,nutritionally balanced diet,controlling of salt intake,regular body exercises and to maintain a proper body weight.Factors related to depression symptoms were sore breasts,constipation,dry skin,lower abdominal pain.The correlation between climacteric syndrome and depressive symptom was significant.Conclusions The main influencing factor of climacteric syndrome was healthy lifestyle.The climacteric syndrome increases the risk of depressive symptoms.
6.Variable Selection by Orthogonal Descriptors and Prediction of Rf Value of Phenol and Aniline Derivatives
Wenjun ZHANG ; Lu XU ; Yuhua QI
Chinese Journal of Analytical Chemistry 2001;29(2):178-181
Orthogonal descriptors is a viable method for variable selection, but this method strongly depend on the orthogonalisation ordering of the descriptors. In this paper, we compared the different methods used for order the descriptors. It showed that better results could be achieved with the use of backward elimination ordering. We predieted Rf value of phenol and aniline derivatives by this method, and compared it with classical algorithms such as forward selection, backward elimination, and stepwise procedure. Some interesting hints were obtained.
7.Preliminary study about the correlation between arterial iodine fraction and Child -Pugh staging of liver cirrhosis
Lu SHI ; Jinyang YU ; Wenjun ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2016;23(6):856-858
Objective To explore the correlation between arterial iodine fraction ( AIF) obtained with energy spectrum CT and Child-Pugh staging of liver cirrhosis.Methods Retrospectively analyzed the Child-Turcotte-Pugh of hospitalized 80 patients diagnosed as liver cirrhosis (15 cases of Child -A,40 cases of Child -B,and 25 cases of Child-C) and CT examination results.HD750 spectral three-stage CT scanning was conducted in all patients.AIF was calculated with energy spectrum analysis software,and the correlation between AIF and Child-Pugh staging of liver cirrhosis was explored.Results There was no statistically significant difference in the iodine content of hepatic artery and portal vein among different groups(t=1.786,P>0.05).The hepatic artery iodine score pair-wise analysis among different groups showed that the differences were statistically significant(F=30.45,P<0.05). The hepatic artery iodine score was highest in Child-Pugh C group,secondary in Child-Pugh B group and lowest in Child-Pugh A group.AIF and Child-Pugh staging of liver cirrhosis was significantly correlated.Conclusion AIF of liver cirrhosis reveals the state of liver function and is correlated with Child-Pugh staging,thus can be adopted as a supplement in clinical Child-Pugh staging.
8.Therapeutic Observation of Acupuncture plus Auricular Points for Hemifacial Spasm
Yang CAO ; Miao ZHANG ; Wenjun WANG
Shanghai Journal of Acupuncture and Moxibustion 2015;(9):839-840
Objective To observe the clinical efficacy of acupuncture plus auricular point sticking in treating hemifacial spasm. Methods Fifty-six patients with hemifacial spasm were randomized into a treatment group and a control group, 28 in each group. The treatment group was intervened by acupuncture plus auricular point sticking, while the control group was by ordinary acupuncture, and the clinical efficacies were compared. Results The total effective rate was 89.3%in the treatment group versus 67.7% in the control group, and the difference was statistically significant (P<0.05). Conclusions Acupuncture plus auricular point sticking is an effective method in treating hemifacial spasm.
9.Progress on complete video-assisted thoracic surgery for lung cancer
Wenjun ZHANG ; Mingran XIE ; Dongchun MA
Journal of International Oncology 2015;42(11):860-862
Complete video-assisted thoracic surgery (cVATS) for lung cancer has the advantages of significantly minimal trauma, markedly light postoperative pain and rapid post-operative recovery, which has been increasingly applied in clinic.Its main operation methods consist of lobectomy, segmentectomy, pneumonectomy and sleeve lobectomy.cVATS for lung cancer can achieve the same radical tumor resection and lymph node dissection as the open thoracotomy, which contributes to a satisfactory long-term outcome.
10.The value of preventive tracheal intubation in the first-aid of serious severe trauma
Tianquan LI ; Wenjun ZHANG ; Shiwei XU
Chongqing Medicine 2015;(29):4092-4094
Objective To evaluate the value of early preventive tracheal intubation in the early first‐aid of serious severe trau‐ma and improve the early first‐aid ability of serious severe trauma .Methods Using retrospective study ,among 258 patients of acute airway obstruction caused by severe trauma ,those who have reached the standard of obstruction and respiratory failure according to observation were as the contrast group (n=84) ,and those who had the tendency of airway obstruction instant treatment of preven‐tive trachea intubation were as early preventive tracheal intubation group (n=174) .The average in hospital days ,the occurrence rate of multiple organ failure and death rate were contrasted .Results In the early preventive tracheal intubation group ,in hospital days were 17 .2 on average ,the occurrence rate of multiple organ failure was 44 .59% and the death rate was 10 .67% .In the con‐trast group ,it was 27 .9 d ,67 .51% and 33 .75% ,the two groups had shown significant difference(P<0 .05) .Conclusion Early tra‐chea intubation have a good trachea management of serious severe traumas ,improve inspiration ,shorten the hospitalization days ,and reduce the occurrence rate of complication .It is important to improving rescuing rate .