Objective To investigate clinical features,neuroradiological diagnosis and therapy of moyamoya. Methods 10 cases of moyamoya's clinical features,neuroradiological diagnosis and therapy were analysed retrospec- tively.Results In this group,there were more adults(7 cases) than children patients(3 cases);children patients pre- sented predominantly brain ischemia symptoms;stenosis or occlusion at the terminus of the siphon portions of internal carotid arteries(ICA) and proximal portions of anterior or middle cerebral arteries(ACA or MCA),and abnormal vascular networks at the base of brain were noted by the magnetic resonance angiography(MRA) and digital subtrac- tion radiography(DSA).Conclusion Children patients of moyamoya diseases presents predominantly brain isehemia s yjnptoms.MRA or DSA of brain investigation is the main way to diagnose moyamoya disease in the early age.Early diagnosis and promptly medical intervention are effective ways to improve prognosis of moyamoya disease.

The inner structure and operating principle of non-contact magneto potentiometer are described. The noncontact magneto potentiometer is one of the main parts of the electrocardiographic magnetic sensing position feedback recorder, which is important for the electrocardiograph to operate normally. If magneto potentiometer has any problem, it will result in some faults. Based on the analysis about the common faults, static method and dynamic method are provided. At last, some suggestions and reference are presented for detection and maintenance.

Objective To investigate the effect of pregnant women with hypertensive disorders of COOK cervical dilatation balloon and Dinoprostone Suppositories on the gestation effect and safety of induction.MethodsThe research object from June 2013 to June 2015 in our hospital for pregnant women with hypertensive disorders in pregnancy in 68 cases (all patients with gestational hypertension and mild preeclampsia) were randomLy divided into the observation.Group and control group, 34 cases in each group.The observation group received COOK cervical dilatation balloon induced labor, the control group to implement Dinoprostone Suppositories induction, comparative analysis of observation group and control group, maternal and perinatal situation, mode of delivery, the cervical Bishop score, the degree of pain.Resultsabnormal fetal heart and uterine hyperstimulation, uterine tonic contraction rate of observation group were significantly lower than the control group(P<0.05).The cesarean section rate in the observation group and the control group had no significant difference.After placement, the cervical Bishop score of observation group was significantly higher than that of control group(P<0.05).The pain degree of observation group was significantly lower than that in control group(P<0.05).ConclusionCOOK balloon dilatation of the cervix and Dinoprostone Suppositories, fewer complications, can significantly improve maternal, perinatal and cervical ripening score of Bishop.

Objective To explore the plasma levels and clinical significance of osteoprotegerin(OPG)and receptor activator of nuclear factor kappa B ligand(RANKL)in patients with chronic heart failure(CHF).Methods In 110 patients with CHF and 80 normal controls,the plasma levels of OPG and RANKL were measured by enzyme-linked immunosorbentassay method.Results The plasma level of OPG in patients with CHF[(135.91±41.83)ng/L]was significantly higher than that in normal controls[(90.13±29.09)ng/L](P＜0.05).The plasma level of RANKL in patients with CHF[(90.82±32.14)ng/L]was significantly higher than that in normal controls[(59.78±20.11)ng/L](P＜0.05).The plasma levels of OPG and RANKL increased with the augment of NYHA functional ranking(P＜0.05).The plasma levels of OPG and RANKL had negative relationship with left ventricular ejection fraction(r=-0.33 and-0.36,P＜0.05).Conclusions The plasma levels of OPG and RANKL in patients with CHF are elevated and related with heart function.OPG and RANKL may participate in the occurrence and development of CHF.

Objective To determine the serum level of Visfatin, and observe the effect of short-term treatment of rosiglitazone on it in the patients with type 2 diabetes mellitus. Methods Thirty-three patients with type 2 diahetes mellitus(diabetic group) who were inadequately controlled by suffonylureas were treated with rosiglitazone (4 mg/d) for 12 weeks. Twenty-seven sex-, age- and BMI-matehed non-diabetic subjects (control group) were studied. Determined blood pressure, Visfatin, triglyceride (TG), high density lipopro-tein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), fasting plasma glucose (FPG),2-hoar postprandial glucose (2 h PPG), fasting insulin (FINS)in all subjects and free fatty acid (FFA), high sensitive C-reactlve protein (hs-CRP) and glyeosylated hemoglobin (GHbA1c), abdominal fat distribution before and after treatment with rosiglitazone in diabetic group respectively. Results The level of serum Visfatin was lower in diabetic group than that in control group [(24.53±9.22) μg/L vs (53.10±27.00)μg/L, P<0.01 ], and it was higher after treatment with rosiglitazone for 12 weeks, but there was no significant difference [(24.53±9.22)μg/L vs (32.62±24.89) μg/L, P>0.05]. Visfatin was correlated significantly with systolic pressure (r =-0.29, P=0.02), FPG (r=-0.40, P=0.001 ), 2 h PPG (r=-0.34, P=0.009 ),LDL-C (r=0.26,P=0.049) and FFA (r=0.44,P=0.009) respectively. In a linear stepwise regression analysis, FFA showed significant correlation with serum Visfatin levels (r2=0.30,f=7.707, P=0.009).Conclusions The level of serum Visfatin is lower in type 2 diabetes mellitus, and it is related significantly with glucose and lipid metabolic factors. The short-term treatment with rosiglitazone can't increase the serum concentration of Visfatin in the type 2 diabetes mellitua.

Objective To evlauate the effect of pulmicort respule combined with solution salbutamoI aerosol on the treatment of bronehiolitis.Methods 65 cases of bronchioiltis were randomly divided into two groups.solution saltutamol inhalation group or pulmicort respule combined with solution salbutamoI group,the time of easing asthma symtpoms was assessed.Results Therapeutic group cure rate is higher than the control group(87.9%/62.5%,P＜0.01),there is significant difference.Observation group duration of symptoms was significantly shorter than the oontrol group(P＜0.01),the difference is significant.Condmlon Pulmicort respule combined with solution salbutamol has significant therapeutic effect on the treatment of bronchiolitks,there are obvious advantages.

Skeletal muscle is essential for the glucose disposal in organism, which is one of the major sites of insulin resistance.The over-activity of classical renin-angiotensin system ( RAS) induces the oxidative stress, leads to the impairment of insulin signaling and glucose transport, resulting in insulin resistance of skeleton muscle.The activation of non-classical RAS by inhibiting classical RAS activity, can ameliorate insulin resistance in skeletal muscle tissue.

OBJECTIVE:To explore the effects of dual-phase insulin aspart with different dosing regimens on the related indica-tors of type 2 diabetic (T2DM) patients with poor glycemic control. METHODS:70 T2DM patients with poor glycemic control were randomly divided into group A and group B. All patients were given metformin and stopped other antidiabetic drugs;based on it,group A was additionally given Dual-phase insulin aspart injection,0.5 U/(kg·d),in the morning and evening before a meal by subcutaneous injection;group B was given Dual-phase insulin aspart injection,0.5 U/(kg·d),once before lunch time for 6-10 U and other twice in the morning and evening before a meal by subcutaneous injection. Both groups were treated for 12 weeks. Glu-cose control rate,glucose control time,and glucose indicators,daily fluctuations of glucose before and after treatment and incidenc-es of hypoglycemia and adverse reactions in 2 groups were observed. RESULTS:Glucose control rate in group B was significantly higher than group A,glucose control time was significantly shorter than group A,incidence of hypoglycemia was significantly low-er than group A(P<0.05). After treatment,glucose indicators and daily fluctuations of glucose in 2 groups were significantly lower than before,and group B was lower than group A(P<0.05). There were no obvious adverse reactions during treatment. CONCLU-SIONS:Conpared with 2 times a day,Dual-phase insulin aspart with 3 times a day for administration can effectively improve the glucose control rate and glucose levels in the treatment of T2DM patients with poor glycemic control,with good safety.

Objective To explore the feasibility of laparoscopy-assisted total mesorectal excision(TME) for anterior resection of rectal cancer.Methods The clinical records of 42 patients with rectal cancer who underwentlaparoscopic TME from April 2006 to July 2008 were analyzed retrospectively.Results All the laparoscopic TME with anal sphincter preservation operations were successful;no case was converted to open procedure.The distal end of rectum was anastomosed by a reusable linear stapler.The average operative time was 195 min(170-230 min) and the operative blood loss 15 mL(10-30 mL).The time for bowel functionrecovery was 32 hours.One patient had postoperative dysuria,and one had intraoperative subcutaneousemphysema.No anastomotic leakage or infection of incisional wound occurred.Conclusions Laparoscopy-assisted anterior resection for rectal cancer is safe and feasible.

Objective To investigate the relationship between apoptosis of peripheral blood lymphocytes (PBLCs) and impaired immunity by assessing the apoptosis and expression of Fas and Bcl-2 in PBLCs of patients with secondary syphilis. Methods Flow cytometry (FCM) was used to detect PBLC apoptosis as well as Fas and Bcl-2 expression in 33 patients with secondary syphilis and 30 normal controls. Results The Fas expression on PBLCs and CD4+ cells was significantly higher in patients than that in controls (P 0.05). The apoptosis levels were significantly higher in PBLCs and CD4+ cells in patients than those in controls (P 0.05). In patients group, the apoptosis levels of both PBLCs and CD4+ cells had a positive correlation with the Fas expression (r = 0.68, P