1.Clinical analysis of 10 cases of moyamoya disease
Chinese Journal of Primary Medicine and Pharmacy 2006;0(08):-
Objective To investigate clinical features,neuroradiological diagnosis and therapy of moyamoya. Methods 10 cases of moyamoya's clinical features,neuroradiological diagnosis and therapy were analysed retrospec- tively.Results In this group,there were more adults(7 cases) than children patients(3 cases);children patients pre- sented predominantly brain ischemia symptoms;stenosis or occlusion at the terminus of the siphon portions of internal carotid arteries(ICA) and proximal portions of anterior or middle cerebral arteries(ACA or MCA),and abnormal vascular networks at the base of brain were noted by the magnetic resonance angiography(MRA) and digital subtrac- tion radiography(DSA).Conclusion Children patients of moyamoya diseases presents predominantly brain isehemia s yjnptoms.MRA or DSA of brain investigation is the main way to diagnose moyamoya disease in the early age.Early diagnosis and promptly medical intervention are effective ways to improve prognosis of moyamoya disease.
2.Operating Principle and Fault Analysis for Electrocardiographic Magneto Potentiometer
Chinese Medical Equipment Journal 1993;0(06):-
The inner structure and operating principle of non-contact magneto potentiometer are described. The noncontact magneto potentiometer is one of the main parts of the electrocardiographic magnetic sensing position feedback recorder, which is important for the electrocardiograph to operate normally. If magneto potentiometer has any problem, it will result in some faults. Based on the analysis about the common faults, static method and dynamic method are provided. At last, some suggestions and reference are presented for detection and maintenance.
3.Analysis of the effect of abortion of pregnant women with hypertensive disorders of COOK and Dinoprostone Suppositories on the balloon dilatation of the cervix during pregnancy
Chinese Journal of Biochemical Pharmaceutics 2017;37(6):358-360
Objective To investigate the effect of pregnant women with hypertensive disorders of COOK cervical dilatation balloon and Dinoprostone Suppositories on the gestation effect and safety of induction.MethodsThe research object from June 2013 to June 2015 in our hospital for pregnant women with hypertensive disorders in pregnancy in 68 cases (all patients with gestational hypertension and mild preeclampsia) were randomLy divided into the observation.Group and control group, 34 cases in each group.The observation group received COOK cervical dilatation balloon induced labor, the control group to implement Dinoprostone Suppositories induction, comparative analysis of observation group and control group, maternal and perinatal situation, mode of delivery, the cervical Bishop score, the degree of pain.Resultsabnormal fetal heart and uterine hyperstimulation, uterine tonic contraction rate of observation group were significantly lower than the control group(P<0.05).The cesarean section rate in the observation group and the control group had no significant difference.After placement, the cervical Bishop score of observation group was significantly higher than that of control group(P<0.05).The pain degree of observation group was significantly lower than that in control group(P<0.05).ConclusionCOOK balloon dilatation of the cervix and Dinoprostone Suppositories, fewer complications, can significantly improve maternal, perinatal and cervical ripening score of Bishop.
4.The changes and clinical significance of osteoprotegerin and receptor activator of nuclear factor kappa B ligand in patients with chronic heart failure
Pengkang YANG ; Wenjun LIU ; Juan WU
Chinese Journal of Postgraduates of Medicine 2012;(31):11-13
Objective To explore the plasma levels and clinical significance of osteoprotegerin(OPG)and receptor activator of nuclear factor kappa B ligand(RANKL)in patients with chronic heart failure(CHF).Methods In 110 patients with CHF and 80 normal controls,the plasma levels of OPG and RANKL were measured by enzyme-linked immunosorbentassay method.Results The plasma level of OPG in patients with CHF[(135.91±41.83)ng/L]was significantly higher than that in normal controls[(90.13±29.09)ng/L](P<0.05).The plasma level of RANKL in patients with CHF[(90.82±32.14)ng/L]was significantly higher than that in normal controls[(59.78±20.11)ng/L](P<0.05).The plasma levels of OPG and RANKL increased with the augment of NYHA functional ranking(P<0.05).The plasma levels of OPG and RANKL had negative relationship with left ventricular ejection fraction(r=-0.33 and-0.36,P<0.05).Conclusions The plasma levels of OPG and RANKL in patients with CHF are elevated and related with heart function.OPG and RANKL may participate in the occurrence and development of CHF.
5.Effect of pulmkort respule combined with solution salbutamol aerosol on bronchiolitis
Yanlin LI ; Xiaoping WU ; Wenjun LI
Chinese Journal of Primary Medicine and Pharmacy 2008;15(8):1279-1280
Objective To evlauate the effect of pulmicort respule combined with solution salbutamoI aerosol on the treatment of bronehiolitis.Methods 65 cases of bronchioiltis were randomly divided into two groups.solution saltutamol inhalation group or pulmicort respule combined with solution salbutamoI group,the time of easing asthma symtpoms was assessed.Results Therapeutic group cure rate is higher than the control group(87.9%/62.5%,P<0.01),there is significant difference.Observation group duration of symptoms was significantly shorter than the oontrol group(P<0.01),the difference is significant.Condmlon Pulmicort respule combined with solution salbutamol has significant therapeutic effect on the treatment of bronchiolitks,there are obvious advantages.
6.Study on the Correlation Between Iron Deficient Anemia and Pregnant Weeks in Gravida
Rufang LIAN ; Wenjun ZENG ; Liping WU
Journal of Chinese Physician 2001;0(08):-
Objective To Study on regularity of iron deficient anemia(IDA) in gravida, provide preventive methods and improve hygienic quality.Methods IDA incidence rate of 12W~19W, 20W~27W, 28W~35W, 36W~pregnant duration were anlyzed in 521 gravida.Results The incidence of IDA in gravida was 16 87% and increased with the development of pregnancy.After 20 weeks of pregnancy,the incidence of IDA markedly increased accompanied with by the decreased Fe, SF and TS, especially during the 28~35 weeks of pregnancy, which reached the peak with the anenia incidence of 26 37%,and 80 50% of cases was irom deficient symptom,it suggesting iron deficiency in this stage and Fe, SF, TS decreased to the lowest level and the stored iron was almost exhausted and ZPP increased.Conclusions After 12 weeks of pregnancy,gravida should be supplemented with iron agent. It's also suggested that those gravida with gestational age older than 28 weeks with the Hb levels of less than 105g/L should be considered as IDA and should be treated with iron supplement. [
7.Peripheral Blood Lymphocytes Apoptosis and Expression of Fas and Bcl-2 in Patients with Secondary Syphilis
Wenjun ZENG ; Yiming FAN ; Zhihua WU
Chinese Journal of Dermatology 2003;0(12):-
Objective To investigate the relationship between apoptosis of peripheral blood lymphocytes (PBLCs) and impaired immunity by assessing the apoptosis and expression of Fas and Bcl-2 in PBLCs of patients with secondary syphilis. Methods Flow cytometry (FCM) was used to detect PBLC apoptosis as well as Fas and Bcl-2 expression in 33 patients with secondary syphilis and 30 normal controls. Results The Fas expression on PBLCs and CD4+ cells was significantly higher in patients than that in controls (P 0.05). The apoptosis levels were significantly higher in PBLCs and CD4+ cells in patients than those in controls (P 0.05). In patients group, the apoptosis levels of both PBLCs and CD4+ cells had a positive correlation with the Fas expression (r = 0.68, P
8.Effects of Dual-phase Insulin Aspart with Different Dosing Regimens on the Related Indicators of Type 2 Dia-betic Patients with Poor Glycemic Control
Lingxiao ZHANG ; Wenjun WU ; Weibin ZHAN
China Pharmacy 2015;26(33):4644-4646
OBJECTIVE:To explore the effects of dual-phase insulin aspart with different dosing regimens on the related indica-tors of type 2 diabetic (T2DM) patients with poor glycemic control. METHODS:70 T2DM patients with poor glycemic control were randomly divided into group A and group B. All patients were given metformin and stopped other antidiabetic drugs;based on it,group A was additionally given Dual-phase insulin aspart injection,0.5 U/(kg·d),in the morning and evening before a meal by subcutaneous injection;group B was given Dual-phase insulin aspart injection,0.5 U/(kg·d),once before lunch time for 6-10 U and other twice in the morning and evening before a meal by subcutaneous injection. Both groups were treated for 12 weeks. Glu-cose control rate,glucose control time,and glucose indicators,daily fluctuations of glucose before and after treatment and incidenc-es of hypoglycemia and adverse reactions in 2 groups were observed. RESULTS:Glucose control rate in group B was significantly higher than group A,glucose control time was significantly shorter than group A,incidence of hypoglycemia was significantly low-er than group A(P<0.05). After treatment,glucose indicators and daily fluctuations of glucose in 2 groups were significantly lower than before,and group B was lower than group A(P<0.05). There were no obvious adverse reactions during treatment. CONCLU-SIONS:Conpared with 2 times a day,Dual-phase insulin aspart with 3 times a day for administration can effectively improve the glucose control rate and glucose levels in the treatment of T2DM patients with poor glycemic control,with good safety.
10.Study on method for establishing the relationship between chromatographic fingerprints
Zhangzhao JIN ; Wenjun WU ; Ming ZHU ;
Chinese Traditional Patent Medicine 1992;0(01):-
Objective: To discuss the method for establishing the relationship between chromatographic fingerprints and its usage in process control. Methods: The relationship between chromatographic fingerprints of a fermentation product Ganoderma capense and its finished preparation had been developed according to guidance on fingerprint of Chinese traditional medicinal medica. As for peaks whose acceptance criteria of relative area should be set, their relative areas in chromatographic fingerprints of raw material and its finished product, the ratios of relative areas of peaks from raw material to those from finished product and their relative standard differences were calculated. Results: The relative standard differences of the rations of all peaks whose acceptance criteria areas should be set, were less than 8%. Conclusion: The results show that the rations and RSDs are enough to represent the quantitave relationship between chromatographic fingerprints, and the acceptance criteria of RSD should be less than 10% (n≥10). The quality of finished product can only be assured if the acceptance criteria of relative areas of peaks in chromatographic fingerprint of raw material are tighter than those set according to guidance, and the manufacture process keeps consistency.