1.Effects of budesonide suspension combined with terbutaline on the VAP and rehabilitation of thoracic surgery
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):295-297
Objective To investigate the effect of budesonide suspension combined with terbutaline on the ventilator-associated pneumonia (VAP) and rehabilitation in patients undergoing thoracic surgery. Methods Fifty-five patients underwent thoracic surgery from June 2006 to January 2017 in our hospital. The patients were treated with budesonide suspension combined with terbutaline atomization solution for inhalation. Forty patients with thoracic surgery were selected as the control group. Comparison of the two groups after the blood gas indicators, the incidence of VAP, mechanical ventilation and hospital stay. Results There was no significant difference in white blood cells, neutrophils and CRP between the two groups.The oxygen saturation of the observation group was higher than that of the control group, the arterial oxygen partial pressure was higher than the control group, PaCO2 was lower than the control group, the difference was statistically significant (P<0.05). The VAP of the observation group was lower than that of the control group. The time of mechanical ventilation was shorter than that of the control group. The hospitalization time was shorter than that of the control group, the difference was statistically significant (P<0.05). Conclusion The combination of budesonide suspension and terbutaline atomization can improve the postoperative effect of thoracic surgery and reduce the incidence of postoperative VAP and promote the early rehabilitation of patients.
2.The effect of anterior fusion with the internal fixation in treatment of fracture-dislocation complicated with spinal cord injure
Chinese Journal of Primary Medicine and Pharmacy 2011;18(3):317-318
Objective To study the the effect and rate of complications of anterior fusion with the internal fixation in treatment of fracture-dislocation complicated with spinal cord injure. Methods 46 patients with fracturedislocation complicated with spinal cord injure were selected as group A 23 cases and group B 23 cases according to the methods of treatment,group A was treated with anterior fusion with the internal fixation,group B was treated with cervical posterior, then the total effective rate, surgical time, the rate of complications, ASIA scores and SF-36 scores before and after the treatment of the two groups were studied. Results The total effective rate of group A(91.3% )was higher than that (73.9%) of group B ( 17/23 ) ( x2 = 6. 38, P < 0. 05 ), surgical time ( 83.6 ± 23.5 ) min of group A was shorter than that of group B( 106.8 ±25. 1)min(t =5.37,P <0. 05) ,the rate[13.0% (3/23)]of complications of group A was lower than that of group B[26. 1% (6/23)] ,ASIA scores and SF-36 scores of group A after the treatment were better than those of group B(P <0. 05) ,there were significant differences. Conclusion The effect of anterior fusion with the internal fixation in treatment of fracture-dislocation complicated with spinal cord injure was better,and the the rate of complications was lower,and it was worthy of exploitation and promotion.
3.Surgical treatment of pancreatic cancer: present status and future
China Oncology 2009;19(8):570-573
The incidence of pancreatic cancer has steadily risen in the past decades. Radical resection is still the best option for treatment of pancreatic cancer. Great progress has been achieved in pancreatic surgery;the mortality and morbidity have decreased dramatically, but long term survival after resection is still dismal. Standard pancreaticoduodenectomy is recommended now for pancreatic head cancer. Extended lymphadenectomy could not improve the prognosis of pancreatic cancer patients. Total pancreatectomy is suitable for some IPMNs patients, rather than a routine for pancreatic cancer patients. The current status and future of surgical treatment for pancreatic cancer will be summarized here.
5.Variation of plaque pH values after chewing xylitol gum
Yan SI ; Weijian WANG ; Wenhui WANG
Journal of Practical Stomatology 1995;0(04):-
0.05). When comparing the pH value of xylitol gum with the pH value of 0.1 kg/L sucrose solution, and comparing that with the sucrose gum, significant difference could be found between the changes of pH values at different time points (P
6.Short-term and Long-term Efficacy of Arthroscopic Debridement,Lateral Patellar Decompression,and Rehabilitation Therapy for Osteoarthritis of the Knee Joint
Yubin WANG ; Huifang WANG ; Wenhui ZHU
Chinese Journal of Minimally Invasive Surgery 2005;0(08):-
Objective To study the short-term efficacy of arthroscopic debridement,lateral patellar decompression,and rehabilitation thearpy for osteoarthritis of the knee joint,and to discuss the long-term outcomes of the treatments.Methods A total of 85 cases of osteoarthritis that were diagnosed according to the clinical diagnostic criteria of ACR were enrolled in this study.The patients were randomly divided into groups A(39 cases) and B(46 cases) to underwent arthroscopic debridement and arthroscopic debridement combined with lateral patellar decompression respectivley.All the operations were performed by a same surgeon.Postoperative rehabilitation thearpies were carried out by one group of therapist.The Lysholm,HSS,and PPI scores were evaluated before the operation,as well as patellar tilt test and patellar gliding test.The examinations were repeated in 3 and 6 months respectivley after the surgery.Results In group A,the scores of Lysholm,HSS,and PPI determined at month 3 were significantly higher than those before the operation,but not changed markedly at month 6.Whereas,in group B,the scores kept being increased after the surgery.At month 3,the scores in group A were higher than those in group B,however,at month 6,the Lysholm score in group B was higher than that in group A.Conclusions Arthroscopic debridement and postoperative rehabilitation are effective for imroving the symtoms and knee function in patients with osteoarthritis and limited ROM of the patella.Combining with lateral patellar decompression,the treatments can achieve better outcomes in 6 months.
7.THE PROCESS DESIGN AND ANALYSIS OF THE PERIOPERATIVE INFORMATION MAN-AGEMENT SYSTEM
Beili HUANG ; Yongju YI ; Wenhui WANG
Modern Hospital 2015;(10):136-139
Objective Improving the hospital operation management , preparing for the establishment of the digital operation room and achieving the fine management goal .Methods Based on the actual medical and clinical demand, combined with the standard of the operation management , designed and analyzed the management rules and processes of the perioperative information management system .Results Straightened out the information management rules and procedures of the operation room , strengthened the communication , feedback and sharing of the periopera-tive medical information , and improved the work efficiency , the operation quality and the utilization rate of the opera-tion room.Conclusion The smooth management process and the efficient use of information are the keys to promote the hospital management by means of informationization .
8.Voltage-gated potassium channels in cognitive dysfunction
Wenhui YAN ; Meng WANG ; Lina CHEN
Journal of Medical Postgraduates 2015;(11):1218-1222
The growing number of cognitive dysfunction patients is bringing heavy mental and financial burdens to the society and families.Voltage-gated potassium channels (Kv), which consist of delayed rectifier potassium channels and transient outward po -tassium channels , are involved in the incidence of cognitive dysfunction .This review summarized the role of Kv channels in cognitive dysfunction and their relationship with N-methyl-D-aspartic acid receptors ( NMDARs) that play an important role in the process of learning and memory .
9.Vocal Fold Augmentation by Transplantation of Autologous Fat and Fascia: An Experimental Study
Mingdong LI ; Jun SUI ; Wenhui WANG
Journal of Audiology and Speech Pathology 1998;0(03):-
Objective To compare the histological fates and the effects of autologous fat and fascia used as augmentative materials to treat unilateral vocal fold paralysis (UVFP). Methods Vocal fold augmentation with autologous fat and fascia was performed on 2 dogs (group A) to cure glottic insufficiency caused by left vocal fold paralysis. Autologous fat and fascia 0.4 ml were injected respectively into left and right vocal folds of 9 dogs (group B). The dogs of group B were killed after 1,3 and 5 months and the dogs of group A were killed after 8 months. The histology of both substances and the effect of treatment were evaluated. Results Surviving autologous fat grafts was found in the canine vocal fold after 8 months, but the absorption was too rapid to maintain the bulk of grafts, the effect could last no more than 5 months. Autologous fascia also survived after 8 months, Conclusion The results showed that these two augmentative materials were both effective in the treatment of IJVFP. Autologous fat can only be used as short - term augmentative material. However, autologous fascia has a potential use for long - term application to correct glottic insufficiency caused by UVFP and other diseases.
10.Expression of Matrix Metalloproteinase-9 and Interleukin-6 of Amniotic Fluid in Patients with Infection of Amniotic Cavity
Xiaomei ZHOU ; Wenhui YU ; Xialing WANG
Journal of Chinese Physician 2001;0(05):-
Objective To assess the role of matrix metalloproteinase-9(MMP-9) and interleukin-6 (IL-6) of amniotic fluid (AF) in predicting infection of amniotic cavity. Methods Eighty-four cases of sigle foetus women with premature delivery, premature rupture of foetal membranes,or suspicious infection of amnitotic cavity were enrolled in this study. AF was obtained by transabdominal amniocentesis before starting any treatment.Infection of amniotic cavity was defined when AF bacterial culture was positive. The contents of glucose, leukocytes, MMP-9,and IF-6 in AF were determined. Results The levels of MMP-9 and IL-6 in AF were significantly higher in women with infection of amniotic cavity than those in women without. In women with infection of amniotic cavity, MMP-9 level was significantly correlated with IL-6 level (r=0.813,P