1.Application of dual-source CT in the evaluation of hepatocellular carcinoma after transarterial chemoembolization treatment
Ruimei CHAI ; Ke REN ; Sheng QU ; Qiang FU ; Qiang WANG ; Wenheng ZHENG ; Ke XU
Chinese Journal of Radiology 2011;45(10):980-984
ObjectiveTo assess the diagnostic value of dual-energy dual-source CT in detecting the enhancement ofhepatocellularcancer( HCC )aftertransarterialchemoembolization( TACE )treatment.Methods Twenty-seven patients with HCC underwent dual-energy dual-source CT including nonenhanced,arterial,portal,and delayed phases scanning after TACE treatment.Arterial phases were acquired with the dual-energy mode for reconstruction of virtual nonenhanced images and color overlay images.DSAs were performed in all these patients.Two blinded and independent readers evaluated the data in 2 reading sessions:standard nonenhanced,arterial phase,portal phase,and delayed phase images were read in session A,and virtual nonenhanced,arterial phase,portal phase,and delayed phase images in session B.Sensitivity and specificity were calculated,with the DSA data set as the reference standard.The sensitivity and specificity were compared with Chi-square test.Results DSA revealed 63 lesions in 27 patients,and 39 of them had blood supply.Overall sensitivity and specificity were 74.4% (29/39) and 83.3% (20/24) for session A,and 94.9% (37/39),95.8% (23/24) for session B,respectively.The sensitivity of the two reading sessions was significantly different (x2 =6.303,P < 0.05 ),while the specificity was insignificantly different ( x2 =2.009,P > 0.05 ).Conclusion Compared with standard dynamic protocols,an arterial dual-energy dual-source CT scan with reconstruction of virtual nonenhanced and color overlay images enables detection of relapse and intrahepatic metastasis of HCC after TACE treatment with higher accuracy.
2.Endogenous testosterone levels and visuospatial ability
Qiong GAI ; Yueji SUN ; Wenheng SUN ; Fan WANG ; Li SHA ; Ya ZHENG ; Yue JIANG ; Guoqing XU ; Huijuan SHEN
Chinese Journal of Behavioral Medicine and Brain Science 2016;25(3):285-288
To describe the effects of endogenous testosterone levels on the visuospatial ability.Thevisuospatial ability,testosteronewere included as the key words,retrieving 46 papers in the database.35 relevant papers have been reviewed in the paper,as the results,we have found that the visuospatial ability of male was better than female.The performances of the visuospatial tasks in males were associated with the lev-els of endogenous testosterone,and the effects comprised two aspects:the organizational function and activa-tional function of the testosterone.The latter have received more attention from researchers.Until now,most studies of activational effects of testosterone on visuospatial ability remained on the level of behavioral re-search.The mental rotation task,navigation task and virtual reality scenes tasks were implied in these stud-ies.A nonlinear relationship has aroused a great controversy.Latest research suggests that further investiga-tion of the neural mechanisms related to visual-spatial ability is needed,using ERP and MRI techniques,to assess the relationship of endogenous testosterone levels with the relevant neural basis of visuospatial ability.