1.Studies on the effect of exercises to early steroid-induced femoral head necrosis
Wengen HOU ; Changlin HUANG ; Yongjun ZHANG
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
Objective To observe the effects of exercises on early stage of steroid-induced necrosis of the femoral head in rabbits with magnetic resonance imaging (MRI). Methods 24 adult rabbits were divided randomly into three groups, i.e. control group (group A), routine model group (group B) and experimental group (group C) with 8 animals for each group. Dexamethasone (DXM) was administrated in a dosage of 2.5mg/kg via intramuscular route to reproduce the aseptic necrosis of femoral head (ANFH) model in groups B and C, while only isotonic physiological saline was given to the animals in group A. MRI examinations were done at 2nd, 4th, 6th and 8th week after administration of DXM for bilateral femoral heads, and also on a medial coronary area of the hip joints with a fixed area of circumambient soft tissure of 3 mm in diameter. Results At 2nd, 4th, 6th and 8th week after the reproduction of the model, the t2-de3d-sag spot-signals given by MRI in the circumambient soft tissue of hip joints were 56.26?0.45, 58.05?0.27, 59.04?0.29 and 59.23?0.25 in group A, 61.40?0.41, 63.71?0.34, 69.65?0.28 and 71.84?0.3 in group B, and 59.54?0.39, 60.06?0.32, 62.71?0.19 and 63.18?0.40 in group C, respectively. Significant differences existed between each of two groups (F=84.93, P
2.Morphological mensuration of bone moulding reconstruction accelerated by “cyclic intensive training” and the influence of intervention in human beings
Changlin HUANG ; Gang XUE ; Wengen HOU
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
Objective The purpose of this study is to evaluate the effects of intensified cyclic training on bone moulding reconstruction, and to found the scientific basis of intensific cyclic training as a new training methods. Methods 48 male rats were equally divided into two groups: intensive repetitive training group and control group. The upper segment of tibia was harvested from the animals at the 1st, 2nd, 3rd, 4th, 5th and 6th week after the onset of the experiment for the measurement of cortical thickness (CT), mean wall thickness (MWT) and the percentage of osseous surface of trabeculae and surface area of trabecular Absorption (Sr). The data of intensive repetitive trained group were compared with those of the control group. 1 303 recruits were divided into control group and experimental group. In the experimental group, they were trained by intensive repetitive training program instead of the traditional training program. The incidence of stress fracture was compared between two groups. Results CT (1.37?0.09, 1.86?0.14, 1.94?0.23), MWT (56.37?2.52, 57.28?3.01, 58.23?2.93) and Sos (12.29?1.17, 14.61?1.84, 15.51?1.13) were higher in the training group than control groups at the fourth week, the fifth week and the sixth week, respectively (P
3.Effects of intensified training on muscular strength of the ankle and cross-section surface area of Achilles tendon in soldiers
Changlin HUANG ; Jinwei AI ; Wengen HOU
Medical Journal of Chinese People's Liberation Army 1981;0(04):-
Objective The purpose of this study was to evaluate the effects of intensified training on muscular strength of soldiers' ankles and Achilles tendon, and to search for effective training methods through the kinetic study of the ankle joint and cross-sectional area (CSA) measurements of the Achilles tendon. Methods 30 recruits and 30 soldiers enlisted over one year were selected randomly. The recruits underwent an intensified training for eight weeks, and the enlisted soldiers underwent only routine training. The muscular strength of the ankle was tested by CYBEX-6000 isokinetic test system and the cross-sectional area (CSA) of the Achilles tendon was measured in the recruits and the enlisted soldiers before and after the intensified training. Results No difference of CSA of Achilles tendon was found among the recruits before and after the intensified training and the soldiers enlisted over one year (0.64?0.05cm~2、0.67?0.07cm~2、0.65?0.07cm~2) (P=0.698, F=0.361), while the CSA showed a positive correlation with body weight (r=0.446). The isokinetic test results indicated that the muscular strength of the ankle of the recruits was built up obviously after intensified training (P0.05). Conclusion The effects of 8-week intensified training were almost similar to one-year routine training. Enforced training seemed to be able to improve training outcomes in a shorter time. The results that no change in CSA of the Achilles tendon after intensified training indicated that the improvement in ankle muscular strength might be attributed to the moulding reconstruction of tendon function rather than by the enlargement of the tendon.
4.Establishment of clinical diagnostic criteria for and related clinical study on the zero-stage nontraumatic osteonecrosis of femoral head
Changlin HUANG ; Wengen HOU ; Qi CHANG
Medical Journal of Chinese People's Liberation Army 2001;0(12):-
Objective To establish clinical diagnostic criteria for zero-stage non-traumatic osteonecrosis of femoral head,and then to check the accuracy and value of the criteria in clinical application through combined intervention therapy including the administration of traditional Chinese medicine and physical therapy.Methods The clinical data of 258 patients suffering from non-traumatic osteonecrosis of femoral head were retrospectively analyzed.Clinical diagnostic criteria for zero-stage non-traumatic osteonecrosis of femoral head were established based on the analysis.Then a clinical comparative study concerning the criteria was performed,so as to verify its authority.Results The established criteria were proved to be satisfactory.The sensitivity,specificity and accuracy of the criteria were 93.7%,86.4% and 89.7%,respectively.The clinical comparative study showed that the prevalence of non-traumatic osteonecrosis of femoral head in the intervention group(34.2%)was obviously lower than that of the non-intervention group(84.9%,P
5.Clinical observation of combined anterior and posterior surgeries approach for the treatment of lumbosacral tuberculosis in 31 cases
Libin YANG ; Sumin YANG ; Wengen HOU ; Tan LU
Chongqing Medicine 2015;(35):4972-4974
Objective To investigate the safety and clinical effect of combined anterior and posterior surgeries approach for the treatment of lumbosacral tuberculosis .Methods There were 31 cases of low lumbar and sacrum spinal tuberculosis in this se‐ries .All cases that anti‐tuberculosis treatment lasted 3 weeks before the operation received posterior transpedicular screw system in‐ternal fixation ,anterior radical focus debridement and auto‐grafting with iliac bone .Bed rest was for 6-12 weeks after surgery and no brace was needed .Anti‐tuberculosis treatment lasted 12 -18 months .Results The period follow‐up was 12 -43 months and there was one case of the formation of the sinus and bilateral abscess after surgical resection of re‐healing ,and there was no cases of bone block displacement .All tuberculosis lesions were healing .13 cases with neurological symptoms had recovery .There was no spondylolisthesis postoperative follow‐up;The heigh ,kyphosis correction and restore stability of vertebral body were satisfied .The patients had solid bony fusion without internal fixation loosening and rupture after 5-9 months .Conclusion It is a safe and effec‐tive method to treat lumbosacral tuberculosis by posterior transpedicular screw system internal fixation and anterior radical focus debridement with interbody autografting .which can thoroughly clear focus of spinal tuberculosis ,decompress sufficiently spinal cord ,correct effectively the kyphosis deformity and achieve the stability of a strong three‐column .