1.Pathological morphology and surgical treatment of cor triatriatum associated with deformities
Wengen GAO ; Zengwei WANG ; Renfu ZHANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(04):-
Ovbective To summarize the clinic data of pathological morphology,diagnosis,surgical treatment and associated anomalies of cor triatriatum from 37 patients enlisted in this study. Methods Thirty-seven patients,21 males and 16 females with a mean age of (9.8?8.6) years were studied. Clinical pathologic anatomy of cor triatriatum was type I in 2 cases,type IIa in 9,type IIb in 24,and type III in 2. Complete cor triatriatum in 31 cases and incomplete cor triatriatum in 6. Thirty-two cases (86%) accompanied with other cardiovascular anomalies. Diagnosis was made in 16(43%) cases preoperatively. All patients had excision of the fibromuscular membrane through the right atrial transseptal approach. Results The mortality rate in this group was 8.11% (3 of 37 cases). Thirty-four cases were followed up after surgery from 3 months to 15 years was satisfactory. Conclusion Cor triatriatum is a rare congenital cardiac anomaly. Treatment of associated deformities was a committed step in cor triatriatum surgical correction. Result of surgical treatment was satisfactory.
2.Central aorto-pulmonary shunts in the tetralogy of Fallot
Wengen GAO ; Renfu ZHANG ; Zengwei WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(06):-
Objective To evaluate the surgical results of central aorto-pulmonary shunts in the tetralogy of Fallot. Methods Between January 1998 and December 2003, 24 patients with tetralogy of Fallot, 16 males and 8 females, with age from 7 months to 19 years [mean (5.3?4.6) years] and weight from 6.5 kg to 45.0 kg [mean (16.9?9.7)kg], were studied. Central aorto-pulmonary shunts were performed with Teflon artificial blood vessels in 10 cases and varicosity Teflon artificial blood vessels (Gore-Tex) in 14 cases. The diameter of these vessels was 3 mm to 6 mm. Results Ideal pulmonary flow in each patient was obtained. The mean SaO 2 stepped up from 0.67?0.09 to 0.93?0.04 after operation (P
3.Effect of non-pulsatile blood flow on the secretion of calcitonin-gene-related peptide in patients undergoing total cavopulmonary connection.
Zongtao YIN ; Renfu ZHANG ; Jun WANG ; Wengen GAO
Chinese Journal of Surgery 2002;40(9):679-681
OBJECTIVETo study the changes of calcitonin gene-related peptide (CGRP) in patients who underwent total cavopulmonary connection (TCPC) and to assess the effects of non-pulsatile blood flow on the secretion function of the lung.
METHODSTwenty-six patients were divided into 2 groups: study group, 13 patients who underwent extracardiac TCPC, and control group, 13 patients who underwent definitive repair for ventricular septal or atrial septal defect. Blood samples for measurement of CGRP were obtained preoperatively, postoperatively or in the follow-up period. Cardiac index (CI) and pulmonary vascular resistance (PVR) were measured by cardiac catheter.
RESULTSThe plasma level of CGRP was significantly higher in the study group than in the control group. CGRP was negatively correlated with PVR (r = -0.99, t = 9.82, P < 0.05), and positively correlation with CI (r = 0.98, t = 6.95, P < 0.05).
CONCLUSIONSAfter total right heart bypass, the non-pulsatile blood flow in pulmonary circulation may stimulate the lung to secrete CGRP, leading to the decrease of PVR and improve early postoperative recovery.
Adolescent ; Adult ; Calcitonin Gene-Related Peptide ; secretion ; Child ; Child, Preschool ; Fontan Procedure ; Heart Defects, Congenital ; physiopathology ; surgery ; Humans ; Pulmonary Circulation ; Vascular Resistance
4.A study on quality of life in patients with coronary artery bypass grafting surgery
Ai-Ping LI ; Yun-Qing MEI ; Wen-Lin MA ; Xu ZHANG ; Xisheng WANG ; Wengen GAO ; Dayi HU ;
Chinese Journal of Thoracic and Cardiovascular Surgery 2003;0(04):-
Objective To assess the perioperative change in Quality of Life(QoL)in patients who underwent CABG surgery. Methods The Chinese version of the SF-36 and SAQ were sent to participants at baseline and three and six months after CABG sur- gery.Results Angina stability score,one of the five SAQ domains,was lowest and postoperative SAQ domains scores were with sig- nificant improvement from baseline.Many of the dimensions of the SF-36 in postoperative patients were better than baseline.The SF- 36 was also used to evaluate in groups ONCAB and OPCAB,but no difference of the SF-36 subscale scores between the two groups was observed.Conclusion SAQ domains scores were significantly improved in three months and increased further in six months.Many of the dimensions of the SF-36 in postoperative patients were improved than baseline.No difference of the SF-36 subscale scores between the groups of ONCAB and OPCAB was observed postoperatively.