Both aspirin and angiotensin converting enzyme(ACE)inhi bi tors are often used concomitantly in patients with cardiovascular disease.The s afety of the combination has been questioned. The potential antagonistic interac tions between ACE inhibitors and aspirin has become the focus of both increasing research and intense debate,with conflicting conclusions havin g been reported in the literature.We reviewed systematically available literatu re on the interactions between ACE inhibitors and aspirin in hyper- tension,acute myocardial infarction and congestive heart failure and found that further trials are needed to shed light on the effects and mechanism of interaction between these drugs.

OBJECTIVE To investigate the distribution and drug resistance status of urinary tract infections in diabetics and offer scientific basis for reasonable usage of antibiotics.METHODS Pathogenic bacteria isolated from specimens of 236 cases with urinary tract infections were identified and drug susceptibility tests were performed.RESULTS Among 236 strains of pathogenic bacteria,Escherichia coli rated the top one,59.7%.Then Enterococcus rated the second and accounted for 10.6%.The isolates were susceptible to imipenem and amikacin and showed higher drug-resistance to the other common antibiotics.CONCLUSIONS Diabetics easily suffer from urinary tract infections.Drug-resistance of pathogenic bacteria to antibiotics is higher.Therefore,we should take precautions to control the urinary tract infections in diabetics.

0.05). However, the positive rate of re-expressed CD62p declined to (35.2?18.2)% when the platelets stored at -80 ℃ for 48 months, with significant difference with that for 36 months (P

G mutation.

Ojective To determine the risk factors and the clinical distribution of multiple drug resistant bacteria in stroke- associated pneumonia (SAP) patients with multiple drug-resistant bacterial infections from in-tensive care unit, providing guidance for clinical treatment of SAP. Methods A retrospective study was de-signed to analyze the clinical data of the SAP patients from January 2012 to December 2015. Univariate analysis and multivariable regression analysis were taken for risk factors of MDR infections , and investigated the distribu-tion and drug resistance of MDR. Results There were 183 SAP patients, of which 131patients (71.6%) had MDR infection. There are 193 MDR strains in the 131 patients , the first 5 MDR strains were Acinetobacter bau-mannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus and Escherichia coli. MDR in-fection is highly associated with sever unconsciousness , time of stay in ICU longer than 7 days , ventilator time longer than 7 days and late-onset pneumonia and the difference was significant (P < 0.05). Conclusion SAP patients with MDR bacterial infections are in association with the following risk factors: sever unconsciousness , time of stay in ICU longer than 7 days, ventilator time longer than 7 days and late-onset pneumonia. The rate of MDR bacterial infections was high , and these MDR strains were widely different degrees of resistance to many antibiotics.

Objective To observe the effects of Ulinastatin on pulmonary vascular endothelium permeability and respiratory function in patients with extrapulmonary acute respiratory distress syndrome(ARDS exp). Methods The data of 39 patients with ARDS exp were retrospectively analyzed.According to whether treated with Ulinastatin or not, all patients were divided into Ulinastatin group(n = 21)and control group(n = 18); The level of extravascular lung water index (EVLWI), pulmonary vascular permeability index(PVPI) and respiratory function were measured before and after the treatment. Results The mortality rate of Ulinastatin group was lower than that of control group (28.6% vs 38.9%). The time of decreasing EVLWI, PVPI and improving PaO2/FiO and respiratory function in Ulinastatin group was shorter than that of control group, and the effect was superior. Conclusion Ulinastatin could reduce EVLWI and PVPI, improve pulmonary compliance and oxygenation, and reduce mortality rate in patients with extrapulmonary acute respiratory distress.

Objective To investigate the protective effect of physcione on acute liver injury in rats.Methods Acute liver injury rat model was constructed with 2ml/kg CCl_4((?)3 d)via intragastric administration.The serum concentrations of alanine aminotransferase(ALT),aspartate aminotransferase(AST)and tumor necrosis factor (TNF)in different groups were detected.Hepatic histopathology of different groups was also observed to reflect the effect of physcione.Results The serum concentrations of ALT,AST and TNF in physcione group were significantly lower than those of model group(P

0.05).However,during the thawing process of the APCs,four out of ten and three out of eleven APCs samples appeared aggregative reaction after cryo-preservance for 4 and 5 years,respectively.The majority of the samples extensively lost their factor Ⅲ activities in the fifth year storage.When fresh,liquid platelets were stored at room temperature(22 ℃),the in vitro adhesion and agglutination gradually decreased and statistic differences were observed in 72 h(P

Humans ; Influenza A virus ; Influenza Vaccines ; Influenza, Human ; epidemiology ; prevention & control ; virology

0.05).Conclusion:People adjust the immunological function of B cells to normal level in blood donation plastochrone.These undoubtedly provide powerfully experimental data on the enlistment of volunter blood donation.