1.Clinical observation of performing rhegmatogenous retinal detachment surgery under operation microscope
Zhi-Xin, SHEN ; En-Fang, GAO ; Wen-Qing, WENG
International Eye Science 2015;(2):339-341
To compare the effect and advantage of performing rhegmatogenous retina detachment surgery under operation microscope with under direct ophthalmoscopes .METHODS: Ninety - three patients ( 93 eyes ) were randomized to two groups, Group A ( under operation microscope during rhegmatogenous retina detachment surgery, 47 cases ) , Group B ( under direct ophthalmoscopes during rhegmatogenous retina detachment surgery, 46 cases ) . All patients were followed up for 2wk to observe success rate and visual improving rate.RESULTS: Total percentage of success was 95. 74% in group A and 80. 43% in group B. The visual improving rate of group A was 82. 98% and it was 67. 39% in group B. Operative time in group A was significantly shorter than that in group B (P<0. 05). CONCLUSlON: Performing rhegmatogenous retina detachment surgery under operation microscope is ascertaining and it is more effective and handy than performing that surgery under direct ophthalmoscopes.
2.Analysis of iatrogenic retinal breaks compficating pars plana vitrectomy in eyes with idiopathic macular pucker
Wen-Ying FAN ; Jun XU ; Kai MA ; Zhi-Jia HOU ; Nai-Qing WENG ; Ning-Pu LIU ;
Ophthalmology in China 1993;0(04):-
Objective To determine the incidence and risk factors of iatrogenic retinal breaks in eyes undergoing pars plana vit- rectomy for idiopathic macular pucker.Design Retrospective case series.Participant 88 consecutive vitrectomies performed on eyes with idiopathic macular pucker.Method Consecutive vitrectomies performed on eyes with idiopathic macular pucker at Beijing Tongren Eye Center between 2002 and 2006 were retrospectively reviewed.Cases with iatrogenic retinal breaks were recorded and analyzed. Main Outcome Measure Number and location of retinal breaks,and anatomic outcome after surgical managements.Result A total of 88 consecutive vitrectomies were included in the study.Of the 88 eyes,8 eyes had 14 iatrogenic retinal breaks detected,with an aver- age incidence of 9.1%.Peripheral retinal breaks(8.0%)were more common than posterior retinal breaks(1.1%).All peripheral retinal breaks occurred around the selerotomy sites(100%)and the quadrant of predominant hand was involved most commonly(62%).Most of the breaks(88%)were detected during the surgery.All eyes with iatrogenic retinal breaks obtained anatomic retinal reattachment (100%).Conclusion Despite improvements in instrumentation and surgical techniques,iatrogenic retinal break continues to be an im- portant complication of pars plana vitrectomy in eyes with idiopathic macular pucker.This complication tends to occur more commonly at peripheral retina and is mainly selerotomy-related.
3.Treatment of depression fractures of posterolateral tibial plateau through a modified anterolateral approach.
Guo-Jian XU ; Dong WENG ; Ming-Hua XIE ; Wen-Qing LIANG ; Guan-Biao HU ; Yu QIAN
China Journal of Orthopaedics and Traumatology 2015;28(3):256-259
OBJECTIVETo study the therapeutic effects of posterolateral depression fractures of the tibial plateau through a modified anterolateral approach.
METHODSFrom February 2011 to January 2012,13 patients with posterolateral depression fractures of the tibial plateau were treated through a modified anterolateral approach. There were 8 males and 5 females, ranging in age from 28 to 59 years old (49.2 years old on average). Data from patients were collected retrospectively as follows: X-ray, time of fracture healing and the complications of fracture healing. The patients were evaluated both clinically and radiologically according to the Rasmussen score system.
RESULTSAll the patients were followed up, and the duration ranged from 6 to 18 months (mean 13.7 months). All the patients got bony union. The average radiographic bony union time was 15.1 weeks (ranged, 11 to 17 weeks). No case of secondary articular depression was found. No complications such as malunion or joint stiffness were found. But 1 patient had superficial infection and 1 patient had common peroneal nerve injury. According to the Rasmussen score system,the mean radiological score was 16.50 ± 0.67 (ranged, 13 to 18), and the mean functional score was 25.20 ± 2.21 (ranged, 13 to 30). The mean range of knee motion was (125.3 ± 9.3)° (ranged, 0° to 135°).
CONCLUSIONTreatment of depression fractures of posterolateral tibial plateau with a modified anterolateral approach is a safe method with effective exposure, due to its stable fixation and relatively good outcome with minimal soft-tissue complications. It is regarded as an ideal procedure for depression fractures of posterolateral tibial plateau.
Adult ; Female ; Fracture Fixation, Internal ; methods ; Fracture Healing ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Tibial Fractures ; surgery
4.Inhibitory impacts of Niaoluqing on urogenital Chlamydia trachomatis in vitro.
Xiao-Qing ZHANG ; Yuan LU ; Da-Can CHEN ; Wen HE ; Yi WENG ; Da-Yun XU ; Guo-Wei XUAN
National Journal of Andrology 2005;11(11):870-872
OBJECTIVETo explore the inhibitory effects of Niaoluqing, an oral liquid of traditional Chinese medicine, on the growth of urogenital chlamydia trachomatis (Ct).
METHODSNiaoluqing's applying concentration was 1 g/ml and 10 serologically untyped strains of Ct from the STD clinic were used. And the inhibitory effects of Niaoluqing on Ct was evaluated by McCoy cell microculture technique in vitro.
RESULTSNiaoluqing had inhibitory activity for urogenital Ct, and was capable of reducing inclusion numbers notably in the concentrations of 50 to 200 mg/ml. The number and volume of Ct inclusions reduced gradually and disappeared finally with the rising of the medicinal concentration.
CONCLUSIONThe traditional Chinese medicine Niaoluqing has inhibitory effects on the growth of urogenital Ct.
Chlamydia trachomatis ; drug effects ; isolation & purification ; Dose-Response Relationship, Drug ; Drugs, Chinese Herbal ; pharmacology ; Female ; Humans ; Male ; Microbial Sensitivity Tests ; Urogenital System ; microbiology
5.Relationship on the prevalence of physical activity to depressive symptoms and satisfaction of school life among middle school students in Bengbu, Anhui province
Hui CAO ; Qing-wen OIAN ; Ying SUN ; Ting-Ting WENG ; Hui WANG ; Fang-Biao TAO
Chinese Journal of Epidemiology 2012;33(2):154-159
Objective To describe the prevalence and relationship between physical activity (PA),depressive symptoms and school life satisfaction among middle school students in Bengbu,Anhui province.Methods A total number of 5268 boys and girls were analyzed from 4 middle schools.Depressive symptoms were assessed,using the Depression Self-rating Scale for Children,school life satisfaction via the School Life Satisfaction Rating Questionnaire.Self-reported PA and sedentary behaviors were also assessed.Descriptive statistics and logistic regression models were used.Results Adolescents self-reported rates of participating in sufficient moderate,vigorous and insufficient PA were 14.7%,36.0% and 59.1%,respectively.The prevalence rates on depressive symptoms and school life dissatisfaction were 24.4% and 25.9%.After adjusting on sedentary behaviors and other potential confounders,participants who had engaged in sufficient moderate and vigorous PA had odds ratios of 0.73 (0.60-0.89),0.68 (0.59-0.79) and 0.76 (0.63-0.92),0.70 (0.61-0.81) for likelihood of being depressive and school life dissatisfaction,compared to their counterparts who participating in insufficient moderate and vigorous PA.Insufficient PA was positively associated with depression and dissatisfaction of their school lives [OR (95% CI):1.42(1.24-1.63) and 1.45 (1.27-1.66)].Conclusion High prevalence of insufficient PA was seen among adolescents and PA was closely related to the presence of depressive symptoms and school life dissatisfaction among middles school students.
6.Introduction of EOS imaging system and its current research status in evaluating clinical value of lower limb force line.
Qing LI ; Wen-Jie WENG ; Wei-Jun WANG ; Ming-Hui SUN
China Journal of Orthopaedics and Traumatology 2019;32(9):875-878
The principle and technical background of EOS imaging system are introduced. Combining with the publicity of this technology and the existing literature reports, it is known that low dose EOS technology can reduce radiation dose by 5 to 10 times in the course of examination, and micro dose EOS can even reduce radiation dose by 45 times. The image quality is only high or low; the system has EOS 2D and 3D workstations, which can help clinicians to measure and evaluate coronal and sagittal force lines of lower limbs easily. The tilt and torsion of limbs can be measured three-dimensional after three-dimensional model reconstruction in the three-dimensional workstation. Using these results, preoperative evaluation can be carried out. It is helpful for clinicians to evaluate and improve preoperative planning and post-operative measurement and evaluation of surgical effect. In terms of measurement accuracy, a large number of literatures reported that the accuracy of EOS 2D measurement is comparable to that of general radiology measurement, while the accuracy of EOS 3D reconstruction measurement is comparable to that of CT and MRI. Based on the technical characteristics and advantages of EOS, this paper reviews the literature reports and research progress of EOS in evaluating the accuracy of lower limb alignment.
Imaging, Three-Dimensional
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Lower Extremity
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Mechanical Phenomena
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Tomography, X-Ray Computed
7.Sequencing and analysis of the complete genome sequence of WU polyomavirus in Fuzhou, China.
Wen-qiong XIU ; Xiao-na SHEN ; Guang-hua LIU ; Jian-feng XIE ; Yu-lan KANG ; Mei-ai WANG ; Wen-qing ZHANG ; Qi-zhu WENG ; Yan-sheng YAN
Chinese Journal of Virology 2011;27(2):165-169
WU polyomavirus (WUPyV), a new member of the genus Polyomavirus in the family Polyomaviridae, is recently found in patients with respiratory tract infections. In our study, the complete genome of the two WUPyV isolates (FZ18, FZTF) were sequenced and deposited in GenBank (accession nos. FJ890981, FJ890982). The two sequences of the WUPyV isolates in this study varied little from each other. Compared with other complete genome sequences of WUPyV in GenBank (strain B0, S1-S4, CLFF, accession nos. EF444549, EF444550, EF444551, EF444552, EF444553, EU296475 respectively), the sequence length in nucleotides is 5228bp, 1bp shorter than the known sequences. The deleted base pair was at nucleotide position 4536 in the non-coding region of large T antigen (LTAg). The genome of the WUPyV encoded for five proteins. They were three capsid proteins: VP2, VP1, VP3 and LTAg, small T antigen (STAg), respectively. To investigate whether these nucleotide sequences had any unique features, we compared the genome sequence of the 2 WUPyV isolates in Fuzhou, China to those documented in the GenBank database by using PHYLIP software version 3.65 and the neighbor-joining method. The 2 WUPyV strains in our study were clustered together. Strain FZTF was more closed to the reference strain B0 of Australian than strain FZ18.
Adult
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Child, Preschool
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China
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Evolution, Molecular
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Genome, Viral
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genetics
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Genomics
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Humans
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Male
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Molecular Sequence Data
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Phylogeny
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Polyomaviridae
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genetics
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isolation & purification
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Sequence Analysis, DNA
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methods
8.Observation of the efficacy of local multimodal analgesic drugs injection in total hip arthroplasty.
Wen-jie WENG ; Feng WANG ; Dong-yang CHEN ; Tao YUAN ; Zhi-hong XU ; Qing JIANG
China Journal of Orthopaedics and Traumatology 2008;21(11):834-836
OBJECTIVETo study the efficacy of periarticular multimodal analgesic drugs injection in total hip arthroplasty.
METHODSSeventy-six patients undergoing total hip arthroplasty were randomly divided into two groups, 38 patients received periarticular intraoperative injection of multimodal analgesic drugs, and others not do. Pain of patients were evaluated with a visual analog scale postoperatively, and all patients received patient-controlled analgesia for 24 hours after surgery. The consumption of patient-controlled analgesia was recorded at different time-points.
RESULTSCompared to the control group, visual analog scores for pain of the patients of injected group had significantly lower in the post-anesthetic-care unit and four hours after surgery. Patients of the injected group used significantly less patient-controlled analgesia at 6, 12 hours, and over the first 24 hours after surgery than the control group. No adverse effects resulted from the multimodal analgesic drugs were noted in the injected group.
CONCLUSIONPeriarticular injection of multimodal analgesic drugs in total hip arthroplasty can significantly reduce the postoperative pain of patients and the consumption of patient-controlled analgesia.
Aged ; Aged, 80 and over ; Analgesia, Patient-Controlled ; Analgesics ; therapeutic use ; Arthroplasty, Replacement, Hip ; Female ; Humans ; Male ; Pain Measurement ; Pain, Postoperative ; drug therapy ; Treatment Outcome
9.Influence of liver regeneration after partial hepatectomy on the development of liver metastasis of colon cancer in rats.
Bo XU ; Wen-song CAI ; Huan-qing XIAO ; Shu-hua LI ; Jin-tang XIA ; Guang-hui ZHU ; Jie-feng WENG
Chinese Journal of Surgery 2009;47(5):369-372
OBJECTIVETo investigate the stimulated effect of liver regeneration on colon cancer cells in remnant liver in rats.
METHODSRat models with liver metastases or retro-peritoneal metastases of colon cancer were established: animals underwent 37% or 70% liver resection and were compared with a sham laparotomy (15, 25, 15 cases, respectively). Metastases were performed two weeks before resection. Rats were killed 3 weeks after the resection. Total body weight, liver and tumor weights were recorded. The human colon adenocarcinoma cell line Lovo was cultured in the presence of portal serum withdrawn 24 hours and 14 days after partial hepatectomy (PH). DNA synthesis was assessed by flow cytometry analysis for 5-Bromodeoxyuridine (5-BrdU) incorporation.
RESULTSThe tumor growth was accelerated in the remnant liver in 70% PH group, but the tumors in 37% PH group and retro-peritoneal site were not influenced by PH. Compared with the control group, after cultured 72 hours with portal serum withdrawn 24 h after PH, a higher 5-BrdU incorporation was found in the Lovo cell lines (P < 0.05), and it reached the peak after 120 hours of culture (P < 0.05). No difference was found between the groups when cultured with the portal serum withdrawn 14 d after PH (P > 0.05).
CONCLUSIONSPH may accelerate the growth of residual microscopic tumor in the liver which contributes to local recurrence. It has no systemic effect and effects on the cancer cell lines in extrahepatic sites. The excision extension is related to the stimulating effects on the cancer cell line, and subtotal hepatectomy is presumably a major determinant.
Animals ; Cell Line, Tumor ; Colonic Neoplasms ; pathology ; physiopathology ; Hepatectomy ; Humans ; Liver ; physiopathology ; Liver Neoplasms, Experimental ; pathology ; secondary ; surgery ; Liver Regeneration ; Neoplasm Recurrence, Local ; Rats ; Rats, Wistar ; Xenograft Model Antitumor Assays
10.Preliminary clinical outcome of domestic posterior-stabilized total knee arthroplasty.
Zhi-hong XU ; Dong-yang CHEN ; Xu-sheng QIU ; Qing JIANG ; Tao YUAN ; Wen-jie WENG
China Journal of Orthopaedics and Traumatology 2009;22(6):410-412
OBJECTIVETotal knee arthroplasty (TKA) has been widely used in China. More and more attentions are paid to the development of knee prosthesis that fit for the anatomy of Chinese knee. This study is to summarize the surgical techniques and clinical outcome of domestic posterior-stabilized total knee arthroplasty.
METHODSFifty-one patients including 19 males and 32 females underwent TKA by using TC-Dynamic from Jan. 2003 to Dec. 2004 were reviewed. The average age at the time of operation was (76.4 +/- 4.1) years (range, 71 to 84 years). Thirty-seven patients suffered from osteoarthritis and 14 patients were rheumatism arthritis. The courses of the disease ranged from 5 to 40 years and the symptoms were pain and limitation of motion. The knee rating score system (HSS) as well as X-rays of the lower extremity was used to evaluate the clinical results.
RESULTSAll patients were followed up at the 3rd month after TKA and the duration of follow-up of 32 patients ranged from 48 to 61 months. The HSS scores before TKA was (53.3 +/- 6.7) (40 to 59) points. At the 3rd month and 48th month of follow-up, the HSS scores were (86.1 +/- 7.7) (63 to 95) and (83.5 +/- 8.1) (60 to 95) points respectively. The stress X-rays showed preoperative varus deformities from 9 degrees to 30 degrees with the average of (21.0 +/- 5.8) degrees and normal alignment of the lower extremities postoperative. There were no complications related to TC-Dynamic prosthesis and other complications such as infection, prosthetic loosening and dislocation of patella.
CONCLUSIONThere is a good mid-term clinical result of TC-Dynamic knee system, which is designed according to anatomical characteristic of Chinese knee joint. More attention should be paid to this knee system about the long term follow-up.
Aged ; Aged, 80 and over ; Arthritis, Rheumatoid ; surgery ; Arthroplasty, Replacement, Knee ; methods ; Female ; Humans ; Male ; Middle Aged ; Osteoarthritis, Knee ; surgery ; Treatment Outcome