1.Effects of intravitreal injection of Lucentis for anterior segment neovascularization indeced by central retinal vein occlusion
International Eye Science 2016;16(8):1573-1575
Abstract?AIM:To investigate the therapeutic effect of Lucentis in the treatment of anterior segment neovascularization ( ASNV ) induced by central retinal vein occlusion ( CRVO) .?METHODS: This was a retrospective case series study for patients with ASNV secondary to CRVO from January 2013 to December 2014 and treated with intravitreal injection of lucentis. Best visual acuity ( BCVA ) , intraocular pressure ( IOP ) , iris examination and gonioscopy, and if necessary, fluorescein angiography and optical coherence tomography, were recorded.The follow-up time was 6-13mo, the average was 9.1 ± 2.9mo.?RESULTS: Eighteen patients ( 18 eyes ) were treated with intravitreal injection of lucentis;15 patients (15 eyes) of the 18 were treated with panretinal photocoagulation;the other 3 patients 3 eyes were not received the photocoagulation because of vitreous opacity. One patient was treated with glaucoma valve implantation.Six patients with only neovascularization and without glaucoma were improved in visual acuity whose intraocular pressure was controlled after combined treatment.Of the patients with neovascular glaucoma ( n=12 ) , after intravitreal injection of lucentis and panretinal photocoagulation, the IOP was controlled in 4 patients (4 eyes);the IOP of another 7 cases reduced but glaucoma drugs were still needed.One patient ( 1 eye ) received glaucoma valve implantation because of bad control on IOP with worse vision after implantation.The rubeosis disappeared in all patients.?CONCLUSION:Intravitreal injection of lucentis can stop neovascularization and help to control IOP.In the early stage without neovascular glaucoma, lucentis has better effects, which means early detection and intervention are important.
2.Optimization in the construction of the hospital PACS
China Medical Equipment 2014;(10):56-58
Objective:To Integrated PACS and hospital information systems (HIS), and improve the efficiency of PACS, and improve the user experience. Methods:Base on deeply analysis of existing problems in system application, using process optimization, software optimization, and hardware upgrades manner optimize PACS. Results: PACS and HIS realized Integrated, improving the overall performance of the PACS. Enhance the user experience and expand the application scope of PACS. Conclusion: Deeply analysis of existing problems should be done before optimizing the system. Process optimization, software environment optimization should be considered as the most important and upgrading and replacement of the hardware as the secondary.
3.Intravascular malignant lymphomatosis and Asian variant
Journal of Medical Postgraduates 2004;0(01):-
Because absence of lymphoadenopathy, and often associated with haemophagocytic syndrome, the intravascular malignant lymphoma(IVL) is easy mistaken as malignant histiocytosis or connective tissue disease or vasculitis, the diagnosis was difficult while patients were alive. The clinical course of this disorder (IVL)was aggressive and carried a poor prognosis. The cases of this disorder are not too rare to be seen in our country. To enhance one′s ability to differentiate disorder in unknown fever diseases are extremely necessary.
4.Clinical significance of ADAMTS13 activity in thrombotic thrombocytopenic purpura patients
Journal of Medical Postgraduates 2003;0(03):-
A deficient of plasma VW factor-cleaving protease (ADAMTS13) and appearance of unusually large multimers induced platelets aggregation in capillaries and arterioles. It was critical pathogenesis of thrombotic thrombocytopenia purpura (TTP). ADAMTS13 activity has been measured over 1000patients of TTP and hemolysis uremia syndrome (HUS) since 1997. Diagnostic sensitivity and specificity,as well as clinical significance of ADAMTS13 deficiency for TTP patients were evaluated,and synthetical diagnosis basis of TTP were raised.
6.Study Progress of Infantile Spasms in Molecular Genetics
Journal of Applied Clinical Pediatrics 1994;0(04):-
Infantile spasms is a type of refractory epilepsy syndrome.This epilepsy syndrome is characterized by special tonic spasms,a peculiar set of electroencephalographic findings termed hypsarrhythmia,and arrest of psychomotor development in most patients.The etiology is not clearly understood.Recently,mutations of the arista less related homeobox gene(ARX),cyclin-dependent kinase-like 5(CDKL5)/se-rine/threonine kinase 9 gene(STK9),membrane associated guanylate kinase 2 gene(MAGI2),et al,and abnormal chromosome had been found to be responsible for infantile spasms.In this review,progress of infantile spasms in molecular genetics are discussed.
7.Overview of Clinical Diagnosis and Management of Atlanto-axial Joint Disturbance
Chuanjiang XUE ; Xinzhu WEN ; Bo ZHOU
International Journal of Traditional Chinese Medicine 2009;31(2):182-184
Progress in the diagnosis and treatment of Atlanto-axial Joint Disturbance was described on the basis of recent literature. This paper described the definition, anatomy, etiology, diagnosis and treatment with Chinese Medicine of Atlanto-axial Joint Disturbance in detail, and summarized the domestic research progress of this disease.
8.A diagnostic protocol for ipsilateral femoral neck and shaft fractures
Wen XUE ; Lin LIU ; Xiaoli GUAN
Chinese Journal of Orthopaedic Trauma 2009;11(6):501-503
Objective To evaluate a serf-designed diagnostic protoeol which can early detect a femoral neck fracture for patients with a femoral shaft fracture. Methods From September 2005 to June 2007, a self-developed protocol was used to detect an ipsilateral femoral neck fracture for all the patients with femoral shaft fracture who had sought treatment in our department. This protocol consisted of anteroposterior plain radiography of internal rotator, intraoperative fluoroscopy of the hip, a fine (2 mm) cut computed to-mographic scan through the femoral neck, postoperative anteroposterior and lateral plain radiography of the hip in the operating room prior to awakening the patient, at the time of follow-up anteroposterior and lateral plain radiography of the hip in the presence of hip pain. The diagnostic effects of the protocol were compared with those of conventional diagnosis used for all the patients with femoral shaft fracture who had sought treatment in our department from September 2003 to August 2005. A chi-square analysis comparing the protocol group (September 2005 to June 2007) and the non-protocol group (September 2003 to August 2005) was used to assess the early and delayed diagnosis rates for an associated ipsilateral femoral neck fracture. Results The earlydiagnosis rate of an associated femoral neck fracture by the protocol was 93.8%, markedly higher than that by conventional method (46.2%), with statistically significant difference (χ2 = 4.069, P =0.044). Conclu-sion In presence of a femoral shaft fracture. this protocol consisting of plain radiography of intemal rotator, intraoperative fluoroscopy of the hip, fine cut computed tomographic scan of the femoral neck, postoperative plain radiography of the hip, and follow-up plain radiography of the hip in the presence of hip pain, may sig-nificantly improve the diagnostic rate of an associated femoral neck fracture.
10.Advances in research on RNA interference-related drugs for cancer treatment.
Chinese Journal of Oncology 2012;34(11):801-804
Animals
;
Antineoplastic Agents
;
therapeutic use
;
Gene Silencing
;
Genetic Therapy
;
methods
;
Humans
;
MicroRNAs
;
antagonists & inhibitors
;
therapeutic use
;
Neoplasms
;
genetics
;
therapy
;
RNA Interference
;
physiology
;
RNA, Small Interfering
;
antagonists & inhibitors
;
therapeutic use
;
RNA-Induced Silencing Complex
;
metabolism