Objective To investigate the human resources of neurosurgery intensive care unit(NICU)using modified nursing activity score(NAS).Methods NAS was used to investigate the nursing work load of all shifts and compute the needed personnel for every shift,followed by adaption of nursing staff based on the results.Results Based on the scores by NAS,day shift was the heaviest in work load,followed by early night shift and then by late night shift.The differences between day shit and early night shift or late night one were both statistically different(P<0.05 for both).Conclusions The adjustment based on the results by NAS will reduce nursing risk and improve quality of nursing.

Objective: To study the correlation among genetic polymorphism of glutathione S-transferases (GST) T1, M1 and serum creatinine levels,as well as intact parathyroid hormone (PTH) levels in the end stage of renal disease(ESRD). Methods: 118 blood samples of ESRD and 133 of healthy control had been enrolled, and simultaneously the patients' serum creatinine (SCr), blood uria nitrogen (BUN), serum calcium and serum phosphorus were recorded. Polymerase chain reaction (PCR) had been employed to determine the genotypes of GST and immunoradiometric assay was used to determine PTH levels. Results: The distribution frequencies of dual null GST T1 and M1(A), null GST T1 and functional M1 (B), functional T1 and null GST M1(C) and dual functional GST T1 and M1(D) were 16.9%, 11.0%, 44.9%, 27.1% in ESRD and 14.4%, 10.8%, 46.7%, 28.1% in the healthy control, respectively. There was no difference between the two groups (P=0.945); Mean SCr levels of A was higher than that of B (P=0.047) and C (P=0.007) group in ESRD. Conclusion: Distributions of GST Genotypes had no difference among ESRD and healthy control groups; SCr level of dual null GST T1 and M1 (A) was higher than single null GST (B and C) in ESRD. GST may played some roles in metabolism of poisons and protecting cells from the attack of toxic substances.

Objective:To study the expression of D-amino acid oxidase(DAO) in gastric cancer cells and gastric mucosa cells. Methods:The expression of DAO was detected in seven gastric cancer cell lines and a normal gastric mucosa cell line GES-1 by real-time quantitative PCR and in tumor tissues and normal gastric mucous tissues of 46 patients with gastric cancer by RT-PCR.The liver and kidney tissues of nude mouse acted as positive controls.Results:DAO was expressed in the liver and kidney tissues of nude mouse,and DAO expression in kidney tissue was higher than that in liver tissue.DAO was not detected in seven gastric cancer cell lines and the normal gastric mucosa cell line GES-1.Except one tumor tissue sample,DAO was not detected in other gastric cancer tissues and all normal mucosa tissues.Conclusion:DAO was not expressed in gastric cancer cells and gastric mucosa cells.The nutritional treatment of D-Met in place of L-Met could avoid the disadvantage of methionine starvation to important organs,such as liver and kidney.

This paper presents a 3mm fracture model of radial bone of rabbits using operation method. The bone defect was treated with collagen sponge with different pH and different content. After the operation, the body temperature, blood routine measurement, serum antibody, X-ray examination and histological observation in each group were examined to evaluate and study the curative effect and safety of collagen sponge. Collagen sponge had a good result of safety, but there was slightly change in blood routine, serum antibody, and histological observation, etc, with the pH changing and different content of collagen. The results showed that there was no obvious influence of safety to tissues after treatment of the collagen sponge at different pH implanted into bone defect. Collagen sponge at lower pH could promote the healing of bone defect partly, while the safety of collagen sponge with lower content was better.
Animals ; Collagen Type I ; adverse effects ; chemistry ; therapeutic use ; Hydrogen-Ion Concentration ; Male ; Prostheses and Implants ; Proteins ; analysis ; Rabbits ; Radius Fractures ; surgery

The brain science project is another international research program following the human genome project. The combined research of neuroscience and information science will enable people to have a more comprehensive understanding of the healthy and diseased brain.Through reviewing domestic and international literature, this paper summarized the necessity and importance of developing neurology specialist nurses based on the development of brain science project and the policy orientation of China, aiming at providing ideas and direction for the development of neurology specialist nurses.

Objective? To explore the effects of the electronic transfer system on emergency surgery patients. Methods? The electronic transfer system for emergency surgery patients were established. Totally 98 patients who were transferred from the emergency service into the Operation Room using the electronic surgery system were included into the observation group from January to December 2017, while 88 patients who were transferred from the emergency service into the Operation Room using oral and printed transfer records were included into the control group form January to December 2016. The success rate of transfer, patient's and nurse's satisfaction were compared between the two groups. Results? The success rate of transfer using the electronic transfer system for emergency surgery patients was 95.92%, while that of the control group was 77.27% (χ2=14.343,P＜ 0.05). Patient's satisfaction of the observation group was 92.86%, while that of the control group was 59.09% (χ2=29.743,P＜ 0.05). The nurse's satisfaction of the observation group was 95.92%, while that of the control group was 87.50%(χ2=4.432,P＜0.05). Conclusions? The establishment of the electronic transfer system for emergency surgery patients further clarifies the content of transfer, enhances nurses' responsibility and shortens the time of transfer, which plays a preventative and control role in risk management and safety management in emergency surgery patients.

Objective:To summarize the best evidence for prevention and management of aspiration in neurosurgical ICU patients and provide evidence for clinical nursing work.Methods:Relevant evidence on prevention and management of aspiration in neurosurgical ICU patients, including guidelines, consensus, system reviews, and randomized controlled trials (RCTs) which were published from 1st January, 2010 to 30th June, 2019 in any language was retrieved from guideline websites, relevant websites and databases. Two researchers evaluated the quality of the included literature and performed evidence extraction on those literatures that met the quality standards.Results:Totally 9 clinical practice guidelines, 8 expert consensus, 13 Meta analysis / systematic reviews and 10 RCTs were included, which were collected and extracted to form the final version of best evidence for aspiration prevention and management including 10 primary indicators and 29 secondary indicators.Conclusions:Medical staff should take effective measures in early assessment of aspiration risks, artificial airway management, position management, enteral nutrition management, sedation and analgesia management, etc., and reduce the incidence of aspiration in neurosurgical ICU patients by applying the best evidence. In addition, hospitals should provide various forms of education and training to medical staff, form transdisciplinary cooperation teams, and strengthen the prevention and management of aspiration.

Objective:To summarize the best evidence for the prevention and management of aspiration pneumonia in elderly patients to provide a basis for clinical nursing work.Methods:We systematically searched the domestic and foreign guide nets, websites of relevant institutions and databases on the relevant evidence for the prevention and management of aspiration pneumonia, including guidelines, expert consensus, systematic reviews, randomized controlled trials (RCT) , and the search time limit was from January 1, 2010, to June 30, 2020, and the language was not limited. Two researchers evaluated the quality of the included literature, and extracted, analyzed, and integrated evidence that met the quality evaluation criteria.Results:A total of 8 guidelines, 5 expert consensus, 10 systematic reviews, and 19 RCTs were included. The evidence was collected and extracted to form a prevention and management strategy for elderly patients with aspiration pneumonia including 11 first-level indicators and 32 second-level indicators.Conclusions:Medical and nursing staff should take effective measures in risk assessment, posture management, oral management, airway management, medication management, functional exercise and so on to reduce the risk of aspiration. Medical and nursing staff should also strengthen training for their own, elderly patients and main caregivers, and reduce the incidence of aspiration in elderly patients by applying the best evidence, so as to reduce the incidence of aspiration pneumonia.

Objective:To understand the current situation of robot-assisted patient rehabilitation training in neurological disease-related departments of ClassⅢ medical institutions across the country, so as to provide guidance and basis for promoting the improvement of robot-assisted training.Methods:In September 2021, convenience sampling was used to select neurological disease-related departments in Class Ⅲ hospitals from all provinces and cities across the country to conduct a survey on the status of robot-assisted rehabilitation training. A self-designed Hospital Robot-Assisted Training Questionnaire was used for investigation. The survey was conducted using an electronic questionnaire. A total of 250 questionnaires were distributed, and 236 valid questionnaires were recovered, with a valid recovery rate of 94.4%.Results:Among the 236 neurological disease-related departments, a total of 93 (39.4%) departments used robot-assisted rehabilitation training. The robot type was mainly wearable robot, which was mainly used to train lower limb motor function, upper limb motor function, gait ability and so on. A total of 55.9% (52/93) of departments believed that robot-assisted rehabilitation training was more effective than conventional rehabilitation training. Hospital type, department bed turnover times, and daily training time were the main factors affecting the effectiveness of robot-assisted training, and the differences were statistically significant ( P<0.05) . Among the 93 departments that had used robots, 22.6% (21/93) of the departments had not experienced any negative events in the robot-assisted rehabilitation training. The 143 departments that had not yet used robots had a positive attitude towards robots, and the main reasons for not using robots were that robots were too expensive, lacked the guidance of technicians, and were afraid to use them without professional training. Conclusions:Robot-assisted training has been concerned and tried to use by neurological disease-related departments, but the safety still needs to be further enhanced. Medical institutions should formulate robot-assisted rehabilitation training guidelines as soon as possible to guide the application and development of robot-assisted training.

objective: To explore the effect of Standard Operating Procedure on the management of venous blood specimens before laboratory. Methods: Blood collection SOP was established and applied on the management of venous blood specimens before laboratory.Nursing capacity,complication rate,rate of unqualified blood specimens were compared between before and after the SOP applying. Results: Before and after the applying of SOP, the blood collection capacity of nurses were 85.43±5.07,91.28±4.78,the differences were statistically significant(t=-8.104, P=0.024). Before the applying of SOP, amounts of complication about venous blood collection, unqualified blood specimens and unqualified blood specimens which lead by nursing factors were 21, 95, 51, while after the applying, the amounts were 9, 63, 21, the differences were statistically significant (χ²=4.887, 6.052, 6.325, P<0.05). Conclusion Application of Blood collection SOP can promote nursing capacity of blood collection and reduce the incidence of unqualified venous blood specimens,improve the quality of venous blood specimens.