Colorectal polyps are common digestive system diseases in children. The important role of endoscopy in the di-agnosis and treatment of colorectal polyps in children has been recognized. With the continuous development of endoscopic techniques, the diagnosis and treatment of colorectal polyp has become safer, more convenient and more effective. In this re-view, the progress in endoscopy for diagnosis and treatment of colorectal polyps in children has been summarized.

Objective To evaluate the value of spiral CT in diagnosis and treatment of lung lesions in clini-cal work.Methods A retrospective analysis of 100 patients with pathological diagnosis of lung lesions patients were randomly divided into the control group (CT normal scan)and observation group (CT -D post -processing tech-niques).Lungs lesions,hilar and mediastinal lymph node metastasis sensitivity,specificity and accuracy of lymph node metastasis of both group were analyzed.Results In the control group,the diagnosis of lung lesions showed sensitivity of 75%,specificity of 50% and accuracy of 72%;while in the observation group the sensitivity was 80%,specificity was 65 % and accuracy rate was 85%.The differences between the two groups were statistically signficant(χ2 =3.854,4.604,5.007,all P <0.05).50 cases of pathologically verified as lung cancer patients with hilar lymph node metastasis in the control group showed diagnostic sensitivity of 60%,specificity of 72%,accuracy of 70%;while diag-nosed hilar lymph node metastasis in the observation group showed sensitivity of 76%,specificity of 84 percent and accuracy rate of 84%.The differences between the two groups were statistically signficant(χ2 =5.882,4.196,5.534, all P <0.05).50 cases of pathologically verified as lung cancer patients with mediastinal lymph node metastasis in the control group,showed diagnostic sensitivity of 62%,specificity of 57% and accuracy of 60%;in observation group the sensitivity was 72%,specificity was73% and accuracy was 72%.The differences between the two groups were statisti-cally signficant(χ2 =4.342,5.626,4.583,all P <0.05).Conclusion The spiral CT for diagnosis of lung lesions positioning has good effect,and can be widely used in the diagnosis of lung lesions.

College of American Pathologists (CAP) and International Standard Organization (ISO)15189 accreditation provides requirements to the verification and validation tests for clinical molecular diagnostic assays.The article will introduce the requirements in these aspects including the differences between the two accreditation systems,the differences between the verification and validation tests,the essential factors and standardized framework of the verification and validation tests for clinical molecular diagnostic assays.

Objective: To explore the medical service price regulation of theoretic model and reform trends in China. Methods:Qualitative method. Results:Medical care is the service that mix the nature of public service and private service. The price regulation of medical care includes the regulation of price level and price structure. The asymmetric information, equality, externality and monopoly of the medical care are the reasons to implement the price regulation. Ramsey pricing model, investment rate of return pricing model, the price-cap model, yardstick price regulation model and Feldstein pricing model are the general models to implement the price regulation of medical care. Conclusion: China should reform and modify the current price level and structure of medical care based on the above models.

Objective To investigate the content change of aconitine in Radix Aconiti Kusnezoffii in different boiling time. Methods The chromatographic procedure was carried out with methanol-water-chloroform-diethylamide (70∶30∶3∶0.2) as mobile phase at a flow rate of 1.0 mL/min, the column temperature at 30 ℃, and UV detector at 240 nm. Results There was a good linear relationship of aconitine within 0.08-0.8 μg, r=0.999 8 (n=6), and the average recovery rate was 97.16%. The content of aconitine increased gradually in 0-2 h, then gradually decreased. And the reduction was evident particularly during 2-4 hours. Conclusion HPLC method is rapid, simple, accurate, reproducible and reliable for determining aconitine. The content of aconitine can be decreased effectively by boiling 4 hours.

Objective To evaluate the influence and safety of losartan on high sensitive C-reactive protein(hs-CRP) and serum uric acid(UA) of essential high blood pressure(HBP) patients with hyperuricemia (HUA).Methods Eighty HBP patients complicated with HUA were enrolled and divided into the losartan group with losartan 50 mg/d(n =40) and the nifedipine group with nifedipine gastrointestinal therapeutic system (GITS) 30 mg/d (n =40) for 6 months continuously.The serum levels of hs-CRP,UA,hepatic and renal functions,creatine kinase(CK) and blood pressure were measured.Results Compared with before therapy,the systolic blood pressure(SBP),diastolic blood pressure (DBP) were lower in two groups after 6-month treatment and the differences were statistically significant(losartan group:SBP:(158.5 ± 13.2) mmHg vs.(136.7 ± 9.4) mmHg,t =3.50,P ＜ 0.01 ; DBP:(95.6 ± 8.4) mmHg vs.(83.3 ± 6.4) mmHg,t =3.49,P ＜ 0.01 ; nifedipine group:SBP:(157.7 ± 13.9) mmHg vs.(134.6 ± 8.2) mmHg,t =3.53,P ＜ 0.01 ; DBP:(96.1 ± 8.9) mmHg vs.(81.2±6.8) mmHg,t =3.56,P ＜0.01).The differences in terms of systolic and diastolic blood pressure were not significant at post-treatment between losartan and nifedipine group.The serum levels of hs-CRP and UA were significantly lower after 6-month treatment than before treatment in losartan group ((5.68 ± 1.53) mg/L vs.(3.52 ± 0.57) mg/L,t =3.82,P ＜ 0.01 ; (502 ± 45) μmol/L vs.(450 ± 38) μmol /L,t =3.48,P＜ 0.01),but there was no change in nifedipine group(hs-CRP:(5.61 ± 1.64) mg/L vs.(5.33 ± 1.48) mg/L,t =1.34,P ＞ 0.05 ; UA:(499 ± 43) μmol/L vs.(489 ± 42) μmol/L,t =0.68,P ＞ 0.05).There was no significant change regarding of liver and kidney functions and serum CK in losartan group before and after treatment.No adverse reaction occurred in the losartan group.Conclusion Losartan treatment can decrease serum hs-CRP and UA of HBP patients complicated with HUA,and there is no serious adverse reactions and good security during treatment.

Objective: To observe the effects of type 2 diabetes mellitus patients with hypertension on lipid metabolism and insulin sensitivity. Methods: A case-matched study of fasting plasma glucose (FBG), total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HIDL), low density lipoprotein cholesterol (LDL), insulin (FIN), C-peptide (FCP) and insulin sensitivity index (ISI) were detected in type 2 diabetes mellitus patients with and without hypertensiorn. Results: Twenty patients with type 2 diabetes mellitus complicated hypertension had higher TG、 FINS and FCP, lower HDL and ISI levels than 20 patients with type 2 diabetes mellitus without hypertension. Conclusion: Type 2 diabetes mellitus with hypertension had more remarkable lipid metabolic disorder and insulin resistance than type 2 diabetes mellitus without hypertension.

Objective To investigate the relationship between self-efficacy(SE)and subjective wellbeing(SWB)of the elderly in community.Methods 212 elderly people underwent a questionnaire survey by the Memorial University of New Foundland Scale of Happiness and the General Self-efflcacy Scale.Results The level of self-efficacy of the elderly in community was(2.39±0.63),of which impact factor was the level of education and average monthly income per person.The level of SWB was(37.31±7.24),of which impact factor was the level of education and occupation.The level of SE and SWB of the elderly sas mdderately positively correhted,r=0.36,P＜0.01. Conclusions In the practice of community care services,community nurses should take SE theory as a framework and to improve SWB by a vailety of nursing measures.