1.Pulmonary Sclerosing Hemangioma:Comparative Study on Imaging Findings and Pathology
Weiwei HOU ; Yali LEI ; Yunhua WANG
Journal of Practical Radiology 2001;0(07):-
Objective To analyze the imaging characteristics of pulmonary sclerosing hemangioma(PSH) and to improve the accurate rate of its diagnosis before surgery.Methods Imaging findings in 11 cases pathologically proved sclerosing hemangiomas were retrospectively analyzed in comparison with pathology.Results The imaging findings of PSH mostly were solitary masses with homogeneous density,and with smooth margin in 10 cases and irregular margin in 1 case;1 case with slight calcification and 1 case with air-meniscus sign were found.7 cases were homogeneous enhancement and 4 were heterogeneous enhancement on contrast-enhanced scan.The high and low attenuation areas on CT corresponded with angiomatous and cystic areas respecitvely on pathology.Conclusion Chest roentgenogram and unenhanced CT scan of PSH are not of remarkable characteristics,contrast-enhanced CT scan plays an important role in diagnosis and differential diagnosis of PSH.
2.Practice and research of medical students' global health capacity development
Weiwei DU ; Yanwei LIU ; Lei ZHANG ; Qiudan SUN ; Hong LI
Chinese Journal of Medical Science Research Management 2014;27(3):310-314,319
Objective Examine and evaluate the influences and effects of Short-term Overseas Exchange Program (SOEP) on the medical students' global health capacity development.Methods This study collected data through interview and questionnaire of students participated in SOEP,and review of their exchange reports.The quantitative data was analyzed by using the SPSS 17.0 software.Results SOEP is a useful practice of global health capacity development of medicals students,the effects of which are shown in the following aspects:1.Learn and compare different medical education models; 2.Learn and compare different health care systems and models; 3.Cultivate students' global perspective; 4.Understand the different medical culture and medical humanistic philosophy; 5.Promote personal and career development.Conclusions SOEP has fundamental positive effects on the global health conception and capacities development of medical students.Therefore,SOEP should be promoted,and developed in a healthy,orderly and sustainable manner.
3.Application Study of Wavelet Transform in Calcium Sparks Image De-noising
Changhai LEI ; Zhiqiang MA ; Ying TANG ; Weiwei SUN ; Yongji YANG
Chinese Medical Equipment Journal 1989;0(02):-
Objective To study on wavelet transform in calcium sparks image de-noising when excitation contraction cou-pling(ECC) was studied and researched by scanning confocal microscopy,in order to elucidate the mechanism of ECC.But due to the noise exist in most calcium sparks image,it is hardly to recognize and analyze the useful information of calcium sparks.So how to increase the signal-to-noise rate is very important in calcium spark studying.Methods By using the self-developed software based on multi-scale wavelet transform to remove the noise exists in the calcium sparks images.Results The experiments shows that the method can be increased the signal-to-noise rate in about 80 calcium sparks images.Con-clusion The new method for calcium spark expression and spatial and temporal analysis is provided.
4.Research on Technology Roadmap and Basic Data of Traditional Chinese Medicine Health Project Development
Xiling SUN ; Weiwei JIANG ; Donglin YU ; Lei YE ; Mengan LIU
World Science and Technology-Modernization of Traditional Chinese Medicine 2015;(10):1992-1996
This article was aimed to propose and develop traditional Chinese medicine (TCM) health engineering, using modern science and technology, in order to carry out the detection research which reflected TCM features of human functional state. It was an important way to achieve TCM diagnosis and the objective evaluation on therapeutic effects of TCM. The combination of TCM health engineering with information technology, and the formation of TCM functional state intelligent identification system, as well as the extension into the Health Internet of Things (HIT) could provide more accurate and convenient services for human healthcare in the age of big health. And identification on TCM syndromes was the core to achieve this goal. Using characterization data on TCM syndromes could realize the data processing between TCM syndrome and prescription through intelligent computing, in order to form the TCM syndrome differentiation and treatment intelligent system. It had great significance in the promotion of TCM health project.
5.Pretest about the nurse post ability of the leveling exam plan
Xuan SUN ; Xianghong FAN ; Weiwei LEI ; Fei XIE ; Yan LIU
Chinese Journal of Postgraduates of Medicine 2015;38(z1):81-83
Objective To explore and set up the nurse post ability of the leveling exam plan in a third-grade class-A hospital.Methods The entry of more than one year of nurses will participate in the examination of N1-N4 is divided into four levels.According to different levels to set up the post ability of the leveling exam plan,through the review and interview,evaluate its effects and satisfaction in a third-grade class-A hospital.Results After the post ability of the leveling exam plan,nurses of different levels get more satisfied with the score on the assessment form,specialized knowledge,the core system,emergency plan,communication skills,ability of operation and emergency disposal,which significantly higher than the traditional methods,there were statistical differences between two groups.(t value was as follows:1.46,2.13,1.98,2.57,2.69,1.87,P < 0.05),but the difference of foundation knowledge was not obvious (P > 0.05).The new program get higher scores of nurses in critical thinking,clinical care,ethical,legal practice and professional ability,results were significant differences (t value was as follows:2.18,2.01,1.46,2.78,P< 0.05),but the scores in scientific research ability,leadership,interpersonal relationship,education and consulting capacity was not significantly different (P > 0.05).Conclusion It is concluded that nurses of different levels on the leveling exam plan get a higher satisfaction.Through the new program,to assess the level of nurses,effectively improve the capacity on critical thinking,clinical nursing,ethical standards,law practice and professional development.
6.Practice and future development of the medical research summer school
Weiwei DU ; Qiudan SUN ; Lei ZHANG ; Jinbiao HU
Chinese Journal of Medical Science Research Management 2017;30(1):72-76
Objective Peking University Health Science Center,together with Keio University,King's College London and Karolinska Institutet developed a cooperative medical research summer school.It integrates the education methods of lectures,lab rotations and visits etc.,which forms a special model.This study aims to analyze and evaluate the effect,prospect and space for further improvement of the summer school.Methods Program documents review and evaluation,interview and questionnaire survey to teachers as well as students who engaged in such program.Results The sum mer school enhances the research cooperation and communication among faculties and students from participating universities;it is highly appraised by participating teachers and students;students are particularly satisfied in the following aspects:gain knowledge and skills in cross-cultural communication,develop global health knowledge,gain knowledge and skills in research,and also enhance the sense of commitment in research.Conclusions The research summer school can improve the postgrad uate education standard,promote scientific cooperation,and improve students' research capacity.However,there are still some space for further improvement,such as improve the recruitment process;enhance the platform support;strengthen the evaluation,feedback and follow up system;further develop the program in depth and breadth.
7.A Research Progress on the Biosynthesis of Effective Compounds in Salvia Miltiorrhiza
Weiwei LIU ; Junfeng CHEN ; Ying XIAO ; Lei ZHANG ; Wansheng CHEN
World Science and Technology-Modernization of Traditional Chinese Medicine 2016;18(11):1891-1898
Tanshinones and phenolic acids are two major classes of effective compounds in S.miltiorrhizae Radix et Rhizoma.Accumulative levels of these compounds directly determined its quality and efficacy.Presently,for the purpose of understanding the underlying the mechanism behind the biosynthesis and regulation of effective compounds in S.miltiorrhiza,a series of progresses have been pressed ahead.Benefiting from the boost and convenience of high-throughput genomic,transcriptomic,and metabolic analysis methods,remarkable achievements have been accessed in this field.In this paper,a summary for the recent progress have been made with the provision of a reference for better understanding over the quality of S.miltiorrhiza.
8.Method of calling MATLAB in VB application based on ActiveX
Changhai LEI ; Yongji YANG ; Weiwei SUN ; Dongfang LI
Chinese Medical Equipment Journal 2003;0(11):-
Objective To discuss the method of calling MATLAB in VB application program based on ActiveX.Methods MATLAB provided automatic service support to ActiveX,and MATLAB could be called as ActiveX of interpreter through ActiveX automatic interface.Results Good effect was achieved when this method was applied to noise filtering of patch clamp.Conclusion By using this method,users can embedded mix programming in self-developed application software conveniently,thus reducing the difficulties in programming.
9.A marine anthraquinone SZ-685C inhibits cell proliferation and induces apoptosis in GH3 cells
Ni LEI ; Weiwei XIAO ; Zhigang MAO ; Xiaobing JIANG ; Yonghong ZHU
Chinese Journal of Microsurgery 2012;35(5):356-359,442
Objective To explore the effect of SZ-685C on rat pituitary adenoma GH3 cell line.Methods MTT method evaluated its effect of proliferation and inhibitory concentration 50 (IC5o) on GH3 cells,after treated by 0,2.5,5.0,7.5,10.0,12.5,15.0,17.5,20.0 and 30.0 μmol/L SZ-685C for 48 h,GH3 cells were changed to complete medium for 12 d,crystal violet staining was used to investigate colony formation; microscopy and Hoechst 33342 staining assay observed whether the changes of morphological as the result of apoptosis,then detected cell apoptosis by flow cytometry.Results SZ-685C had a dose-dependent inhibitory effect on GH3 cell proliferation and IC50 was (12.9 ± 0.47) μmol/L,MEF(considered as a control group) had little affect in cell proliferation on the concentration of IC50.Inhibitory effects persisted even on removal of SZ- 685C after 12 d,and SZ-685C blocked colony formation ability of pituitary tumor cells.Apoptotic morphological observation of microscope and Hoechst 33342 staining proved apoptosis during treatment of SZ-685C,flow cytometry detection showed that SZ-685C induces 36.4% of apoptosis,while only 2.0% in control group.Conclusion SZ-685C inhibits pituitary tumor cell proliferation and induces apoptosis.SZ-685C can be a new anti-patuitary tumor drug for a further study.
10.Development of a detection system of the enzyme-linked analyzer
Changhai LEI ; Shumei WU ; Leping ZHANG ; Zhinian ZHU ; Weiwei SUN
Chinese Medical Equipment Journal 1993;0(05):-
In allusion to high labor intensity, low working efficiency and high error rate in hospital laboratory, a detection system of the enzyme-linked analyzer based on Multiscan EX instrument is developed. Being easy to operate, the detection system proves effective in enhancing working efficiency. It deserves popularizing because of its comprehensive applications to the detection.