This study explores the teaching effect on theoretical-experimental integrationteaching reform in sanitary chemistry experiment. We carry out various kinds of teaching method in sanitary chemistry experiment by aspects such as theoretical and experimental course package arrange-ment, the module integration of theory and experiment. The practice shows thattheoretical-experimen-tal integration teaching reform practice can improve the quality of sanitary chemistry experiment teaching and cultivate students' comprehensive quality.

The ketogenic diet has been used for the treatment of epilepsy for 90 years, it also has been introduced to our country for more than 10 years.Its clinical efficacy has been recognized,but its antiepilepsy mechanisms are still unclear.This paper reviews its possible antiepilepsy mechanisms from the ion channels, neurotransmitters, neuroprotection, adenosine, mTOR signaling pathway and immune factors.

The main problems existing in the internal control of public medical institutions are pointed out and the suggestions about how to establish and perfect it were proposed, so as to assume its due role, according to its concept and benefits, combined with the analysis of present situation of internal control in public medical institutions in Putuo District.

Non-coding RNAs that can not encoding RNA protein,mainly include microRNAs and long non-coding RNAs,in bacteria,fungi,mammals,and many other biological activities life play a very wide range of regulatory role.More and more clinical researchers have begun to pay attention to the biological function of the non-coding RNAs and the relationship between the various diseases of the body,and people gradually realized that the study of non-coding RNAs has important significance for understanding human disease control and biological evolution.

As an immune regulator, vitamin D plays a role in asthma. In the fetus, vitamin D participates in immune system and lung development. It has been reported that vitamin D deficiency may explain a portion of the asthma epidemic. Beneficial associations have been reported between vitamin D and asthma severity in children. Epidemiologic studies have also suggested that higher prenatal vitamin D intakes have a protective role against wheezing illnesses in young children. In addition, vitamin D may play a therapeutic role in steroid resistant asthmatics and there is interest in using vitamin D therapeutic-ally to complement conventional asthma therapy, such as specific immunotherapy.

ObjectiveTo study the effect of high-dose mifepristone on the expression of hypoxia-inducible factor 1,(HIF-1α) and vascular endothelial growth factor(VEGF) in the endometrial tissue and research the molecular mechanisms of mifepristone in treat ment of endometrial cancer.Methods30 patients with endometrial cancer who were treated were asked to oral mifepristone 100mg/d,the specimens from a biopsy or curettage were taken as the group before treatment,the specimens from surgery were as the group of after treatment.Another 10 cases of normal endometrium were selected as the control group.The expression of HIF-1α and VEGF were examined with immunohistochemistry.ResultsThe expression of HIF-1 α and VEGF(78.6 ± 3.5,92.4 ± 5.1 ) in endometrial cancer was significantly higher than normal endometrium( 192.3 ± 4.7,178.4 ± 3.3,P ＜ 0.01 ),large doses of mifepristone can significantly reduce the expression of HIF-1 α and VEGF in endometrial cancer issues ( 103.2 ± 4.1,118.3 ± 4.9,P ＜0.05).ConclusionOne of the molecular mechanisms of mifepristone inhibits the endometrial cancer was reduced HIF-1α and VEGF expression.

Alveolar fluid transport is closely associated with neonatal lung development neonatal respiratory diseases,such as wet lung,pulmonary hyaline membrane disease,pneumonia,which are related with decreased lung fluid transport.This review introduces the characteristics of neonatal pulmonary fluid balance,including lung fluid secretion and absorption equilibrium,list clinical factors which can increase pulmonary fluid,explain important lung fluid transport mechanisms and their regulations.Inhaling beta agonists or glucocorticoid is a viable therapeutic strategy.

This paper introduces the viewpointins from recent researches about carbohydrate ingestion and mobilization and oxidation of fat during exercise in sports nutrition and interactional influence of carbohydrate and fat metabolism during exercise. Keywords：exercise;carbohydrate;fat;metabolism

This article discussed the author applied the thought of treatment based on syndrome differentiation that acquisitioned from following the master for many years.The three cases of experience in treating insomnia,welling-abscess of the lung and minor chest bind disease applying classical formulae of Xiaochaihu decoction,Weijing decoction and Xiaoxianxiong decoction separately all get preferable clinical curative effect.

Survivin is an apoptosis inhibitor and plays an important role in the development and progression of cancer.It is undetectable in normal adult tissues,but has been showed to be overexpressed in various cancers and has been regarded as a marker of malignancy.And the promoter polymorphism of Survivin gene is closely related to risk of cancer and gene susceptibility,this might provide clues for further elucidation of the correlation of risk of cancer and genetic polymorphism,and for diagnosis,prevention and screening of cancer gene.