1.Solution for fault tolerant technique of network server in hospital
Chinese Medical Equipment Journal 1993;0(06):-
This paper introduces the concept, characteristics and applications of fault tolerant technique, which can ensure high availability of network server.
2.Octreotide for advanced hepatocellular carcinoma:Meta-analysis of randomized controlled trials
Chinese Journal of Postgraduates of Medicine 2010;33(16):28-31
Objective To evaluate the effect of octreotide on the survival of patients with advanced hepatocellular carcinoma(HCC).Methods Electronic databases searches were conducted.Meta-analysis of all randomized controlled trials (RCTs) comparing octreotide versus placebo or no treatment was performed.Results Five RCTs including 579 patients with HCC wers assessed.Meta-analysis of the five studies showed that octreotide had no significant effect on the 6,12 and 24 months survival rates of the patients(6months:OR=1.69,95%CI 0.89-3.21,P=0.11;12 months:OR=2.41,95%CI 0.83-6.93,P=0.10;24months:OR=0.58,95%CI 0.28-1.17,P=0.13).To perform the sensitivity analysis,the blank study,the trial detecting somatostatin receptor expression,the study with short survival or the two trials with short follow-up intervals were excluded,and the results also showed that the octreotide treatment had no significant effect on the 6 and 12 months survival rates.A sensitivity analysis based on two trials indicated that the 24months survival rate of the octreotide group was even lower than that of the control group(OR=0.51,95% CI0.27-0.98,P=0.04).Conclusions This Meta-analysis demonstrates that octreotide could not improve the survival of patients with advanced HCC.The administration of octreotide should not be recommended for the treatment of advaneed HCC.
3.The clinical significance of total serum bile acid test in evaluation of the prognosis of posthepatitis cirrhosis
Chinese Journal of Primary Medicine and Pharmacy 2013;20(11):1641-1642
Objective To explore the clinical significance of serum total bile acid (TBA) test in evaluation of the prognosis of posthepatitis cirrhosis.Methods 92 patients with posthepatitis cirrhosis were selected as the observation group,and divided into A,B,C groups according to the Child-Pugh grades.32 healthy people were selected as the control group.The level of serum TBA was detected and compared.Results The level of TBA in the observation group was (84.26 ±49.03) μmol/L,which was higher than that in the control group[(3.52 ± 2.67) μmol/L](t =17.53,P < 0.01).The level of TBA was gradually increased in Child-Pugh grade A,B,C grade,and the differences were statistically significant (t =3.84,6.21,5.49,all P < 0.05).Conclusion TBA test is benefit for the diagnosis and prognosis of posthepatitis cirrhosis.
4.Academic thoughts on Practice of acupuncture and moxibustion written by CHEN Jingwen, the acupuncture master in the Republic of China.
Chinese Acupuncture & Moxibustion 2015;35(3):305-308
Through the collection of Practice of acupuncture and moxibustion written by CHEN Jingwen, the acupuncture master in the Republic of China, the academic characteristics on acupuncture and moxibusiton were analyzed. The literature comparison method was adopted to compare the works of LUO Zhaoju, ZENG Tianzhi and LI Wenxian, etc. at the same period. It was discovered that CHEN Jingwen was the medical master who systematicly brought up the theory of acupoint properties earlier in the modern times. Classifying drugs based on acupoints was his academic feature. Additionally, the compatibility therapy of Chinese medicine was introduced to explain the essential ideas on the acupoints combination. The treatment was determined on the basis of zangxiang theory and the reinforcing and reducing therapy of acupuncture was emphasized in the determination of treatment and prescription. CHEN Jingwen's theory of acupoint property had been stressed and spread among the medical scholars in the Republic of China and he had made the beneficial exploration for the development of modern acupuncture and moxibustion therapy.
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5.Clinical Observation of 82 Cases of Enuresis Treated by Ginger-partitioned Moxibustion plus Cupping Therapy
Journal of Acupuncture and Tuina Science 2003;1(6):24-25
Purpose: To observe the clinical therapeutic effect in the treatment of enuresis by ginger-partitioned moxibustion plus cupping therapy. Methods: Ginger-par -titioned moxibustion was applied on Guanyuan (CV 4)and bilateral Zusanli (ST 36) and cupping therapy was applied on Shenque (CV 8) in the treatment of 82 cases of enuresis, in comparison with 76 cases treated by Chinese herbal medicine. Results: The effective rate was 84.1% in the treatment by ginger-partitioned moxibustion plus cupping therapy and was 64.5% in the treatment by Chinese herbal medicine. Conclusion: Ginger-partitio -ned moxibustion plus cupping therapy was better than Chinese herbal medicine in the treatment of enuresis (P <0.05).
6.Clinical Observation on 103 Cases of Traumatic Patellar Dislocation Treated with Integrative Traditional Chinese and Western Medicine
International Journal of Traditional Chinese Medicine 2008;30(4):295,309-
Objective To observe clinical effect of traumatic patellar dislocation treated with integrative traditional Chinese and western.Methods 103 patients with traumatic patellar dislocation were randomly divided into a treatment group and a control group.The treatment group was given the therapy of traditional Chinese medicine combined with western medicine,while the control group was treated only with western medicine.After 3 months'treatment,observed it's the clinical effect.Results Efficacy of the treatment group was obviously higher than the control group,with a significant difference (P<0.05).Conclusion The integrative traditional Chinese and western medicine exerts a better effect than the sole therapy of western medicine.
7.CT and MRI on tumor like inflammatory demyelinating disease
Journal of Clinical Neurology 1997;0(06):-
Objective To investigate the clinical and imaging characteristics of tumor like inflammatory demyelinating disease of CNS, We have analyzed the reason of misdiagnosis, and summed up the main point of differential diagnosis.Methods We have analyzed 14 cases which were confirmed as demyelinating disease in pathology after the operation, and all the clinical and image data were included.Results CNS inflammatory demyelinating disease could present edema and mass effect by CT or MRI, there was ring potentialization after enhancement, it was difficulty to distinguish from CNS demyelinating disease. All the 14 patients were misdiagnosis as CNS tumor before the operation.Conclusion CNS inflammatory demyelinating disease could have some atypical representation on CT or MRI image, they were made easily the misdiagnosis. We should get the differential diagnosis by many ways including clinical manifestation, course, laboratory examination and imaging characteristics.
8.Ilaprazole in the treatment of duodenal ulcer:a Meta analysis
Lijun YU ; Weiping HUANG ; Junling HAN
Chinese Journal of Postgraduates of Medicine 2011;34(31):15-17
Objective To systematically review the efficacy of ilaprazole in duodenal ulcer by Meta analysis.Methods Randomized controlled trial (RCT) comparing ilaprazole with other proton pump inhibitors in duodenal ulcer were searohed for Meta analysis.Results Six RCT met the inclusion criteria and 1319 patients were included.Meta analysis showed that the healing rate at 4-week in the dose of ilaprazole 10 mg/d was higher than that in control group [ 89.1% (591/663 ) vs.86.4% (426/493) ],but there was no significant difference (P> 0.05 ).When including high-quality literature,English literature,Chinese literature,or the literature using omeprazole as control,there was no significant difference either (P > 0.05 ).The adverse rate in the two groups had no significant difference [ 9.7% (64/663) vs.12.6% (62/493)] (P >0.05 ).The 4-week healing rate between the doses of ilaprazole 5 mg/d and 10 mg/d had no significant difference [84.7%(138/163) vs.84.0%(131/156)](P>0.05).Conclusions Ilaprazole has high healing rate for duodenal ulcer,with low adverse rate.The effect of the dose ot5 mg/d is comparable to 10 mg/d.
9.Effect of psychological intervention on prevention of postoperation infection in patients with breast cancer
Ling TAN ; Wanting ZHENG ; Weiping HUANG
Chinese Journal of Practical Nursing 2008;24(15):58-59
Objective To discuss the effect of psychological intervention on prevention of posloperation infection in patients with breast cancer .Methods 336 patients with breast cancer after operation were divided into the control group and the intervention group with 168 cases in each group.The control group received routine nursing while the intervention group Was given psychological intervention based upon routine nursing.The incidence of postopemtion infection was observed in the two groups.Results Incidenc of infection took place in 27 patients(8.04%)among 336 cases.The incidence rate infection in the control group was 12.50%,which was evidently higher than that of the intervention group(3.57%),x2=9.06,P<0.01.The infection location and time in the intervention group was better than that of the control group.Conclusion Psychological intervention could reduce the incidence rate of posteperation infection in patients with breast cancer.
10.Study on inhibitory effects and mechanism of amlodipine on human breast carcinoma cell line MCF-7
Wenjing HUANG ; Weiping LI ; Wenjuan SUN
Chinese Pharmacological Bulletin 2009;25(12):1635-1640
Aim To observe the effects of amlodipine on cell cycle,cell cycle-related genes and cyclin expression of human breast carcinoma MCF-7 cells.And to probe effects of amlodipine on cell cycle and its mechanism of human breast carcinoma MCF-7 cells.Methods In vitro growth inhibitory effects of amlodip-ine on human breast carcinoma MCF-7 cells were determined by MTT assay,cell cycle distribution was detected by flow cytometry,the Mrna expression levels of cell cycle-related genes cyclinD1 and p21 were treated by RT-PCR,and the protein expression of cell cycle protein cyclinD1 and p21 were assessed by Western blot.Results With dose and time dependently,amlodipine could inhibit the proliferation of human breast carcinoma MCF-7 cells in vitro.The IC_(50) was 14.439 μmol·L~(-1).When breast cancer cells MCF-7 were treated with 7.22 μmol·L~(-1)(1/2 IC_(50)),14.439 μmol·L~(-1)(IC_(50))and 28.88 μmol·L~(-1)(2IC_(50))amlodipine for 48 h,the ratios in the G_0/G_1 phase were significantly increased as compared with control group(P<0.05).Amlodipine inhibited the expression of Mrna and protein of cyclinD1,while increased the expression of Mrna and protein of p21.Conclusions Amlodipine exhibits obvious anti-tumor activities on human breast carcinoma MCF-7 cells and arrest cell cycle in G_1 phase.The mechanism of G_1 phase arresting may be related to modulating the Mrna and protein expression of cell cycle-related gene cyclinD1 and p21.