2.Real-time Effect of Retaining Needle at Lingtai (GV 10) and Shendao (GV 11) on ST-T Segment on Cardiogram of Angina Pectoris of Coronary Heart Disease
Chengjia LI ; Guannan YANG ; Weijun GONG
Shanghai Journal of Acupuncture and Moxibustion 2016;(1):27-29
Objective To observe the real-time effect of retaining needle at Lingtai (GV 10) and Shendao (GV 11) on ST-T segment on cardiogram in patients with angina pectoris of coronary heart disease (CHD).Method Thirty patients with angina pectoris of CHD who received acupuncture at Lingtai (GV 10) and Shendao (GV 11) were divided into group A with needles retained after insertion of the needles and group B without needles retained. The two groups were observed by using 12-lead electrocardiogram (ECG) before and after treatment, to compare the ST segment and T wave atⅡ,Ⅲ, avF lead and V4, V5, V6lead before and after treatment.Result After treatment, ST segment atⅡ,Ⅲ, avF lead and V4, V5, V6lead was changed significantly in group A (P<0.05). T wave was significantly changed atⅡ,Ⅲ, avF lead after treatment in group A (P<0.05). T wave at V4, V5, V6 lead was significantly changed after treatment in both groups (P<0.01,P<0.05).Conclusion Acupuncture at Lingtai (GV 10) and Shendao (GV 11) can improve myocardial ischemia in angina pectoris of CHD; compared to acupuncture without needles retained, retaining needles after acupuncture can produce a more significant effect in improving the inferior and anterior myocardial walls and a better real-time effect on ST-T on ECG of angina pectoris of CHD.
3.Study of oxaliplatin combined with capecitabine in the preoperative gemcitabine concurrent chemotherapy for improving the local control rate of colorectal cancer and anal sphincter preservation rate
Qiangjun GONG ; Weiyu LI ; Weijun CHEN
Chinese Journal of Primary Medicine and Pharmacy 2017;24(11):1732-1736
Objective To investigate the effect of oxaliplatin combined with capecitabine on the rate of local control and anal sphincter preservation of rectal cancer.Methods Eighty patients with stage Ⅱ/Ⅲ colorectal adenocarcinoma were randomly divided into control group and observation group,each group in 40cases.The patients in the observation group were treated with oxaliplatin and capecitabine.The control group was treated with oxaliplatin combined with leucovorin and 5-fluorouracil.The patients were followed up for 2~4 weeks.The local curative effect, perioperative biochemical index,R0 (excision margin without cancer cell) resection rate and sphincter preserving rate were compared between the two groups.Results In the control group, the short-term curative effect was 47.50%, which in the observation group was 60.00%, the difference was statistically significant (x2=4.22,P<0.05).There were no statistically significant differences in the biochemical indicators between the two groups (all P>0.05).The R0 resection rates of the control group and the observation group were 62.50%,57.50% (x2=0.67,P>0.05).The anal sphincter preservation rates of the control group and observation group were 32.50%,37.50% respectively (x2=0.67,P>0.05).The local control rates of the control group and observation group were 90.00%,92.50%,which of the observation group was higher than the control group, but the difference was not statistically significant(x2 =0.32,P>0.05).Conclusion The combination of oxaliplatin and capecitabine can improve the local curative effect in patients with rectal cancer without affecting the biochemical indicators of perioperative patients, but the effect of R0 resection rate and preserving anus rate in patients with rectal cancer compared with the chemotherapy regimen of FOLFOX4 has no significant difference, it is worthy of clinical promotion.
4.Advance in Spasticity after Stroke(review)
Weijun GONG ; Tong ZHANG ; Xinting SUN
Chinese Journal of Rehabilitation Theory and Practice 2008;14(3):212-213
Stroke is common clinically and spasticity is one of the main symptoms.There is some advance in recognition of the spasticity after stroke in the basic and clinic,but it remains obscure.
5.Cultivating Mode of Postgraduate in Neurological Rehabilitation in Rehabilitation Medicine and Physical Therapy
Weijun GONG ; Fengren ZHANG ; Tong ZHANG
Chinese Journal of Rehabilitation Theory and Practice 2012;18(8):754-756
This article reviewed departed teaching experience and discussed the cultivation mode of postgraduate in neurological rehabilitation
in rehabilitation medicine and physical therapy
6.Effects of Needle Retaining on Haemodynamics of Anterior Tibial Artery During Acupuncture
Tong ZHANG ; Weijun GONG ; Xinting SUN
Chinese Journal of Rehabilitation Theory and Practice 2009;15(11):1044-1045
Objective To study the relationship between needle retaining anddeqi. Methods Manual acupuncture was performed at the left ST36 of 26 naive healthy adult volunteers. Half of them retained the needles for 6 min and others were put the needle out immediately afterdeqi. Hemodynamic parameters of the anterior tibial artery were observed with color Doppler ultrasonography before and at 0, 1, 2, 3, 4, 5 min after acupuncture. Results There was significant difference in Vmax、Vm、Pi and Dist in anterior tibial artery before and 3 min after acupuncture, but wasn't between needle remaining and not. Conclusion Needle retaining cannot change the regional haemodynamics during acupuncture, which suggest it cannot strengthendeqi.
7.Teaching for Students of Rehabilitation Medicine in Neurological Rehabilitation Practice
Lihua CUI ; Weijun GONG ; Lei SHAN
Chinese Journal of Rehabilitation Theory and Practice 2014;20(1):99-100
Neurological rehabilitation involves the most functional impairments. The students of rehabilitation medicine are required to master diagnosis and treatments of diseases, and assessments and rehabilitation of disabilities in neurological field during practice. This article introduced the experience of teaching for the students practised neurological rehabilitation.
8.Progress on breast cancer stem cells as a new target for the studies and treatment of breast cancer
Weijun LIU ; Kunhua WANG ; Kunmei GONG ; Yongxue ZHANG
China Oncology 2010;20(1):66-69
Since the study of the mechanism of breast cancer occurrence and development deepens, breast cancer stem cells are receiving more and more attention. Studies have shown that a group of breast cancer stem cells were undifferentiated, with self-renewal and multi-differentiation potential. These cells have a resistance to chemotherapy, radiotherapy, hypoxic, high tumorigenic, high invasion and metastasis. In breast cancer's recurrence,development, and even metastasis, they play an extremely important role. In-depth study of breast cancer stem cell related signal transduction pathways and the regulation of microenvironment are meaningful for clinical targeted treatment of breast cancer. Therefore, we summarized the latest development on breast cancer stem cells in the treatment of breast cancer.
9.Application of Neural Prosthesis in Rehabilitation of Cervical Spinal Cord Injury (review)
Zilong DIAO ; Xinxin MA ; Xiaoke CHAI ; Ran BAI ; Weijun GONG
Chinese Journal of Rehabilitation Theory and Practice 2017;23(4):394-397
Neural prosthesis control system is based on brain-computer interface and functional electrical stimulation technology, by an-alyzing the electroencephalograph control commands directly into the muscle system or an external device, which compensated efferent pathway from the brain-spinal cord, and recovered motor function of patients with cervical spinal cord injury. This paper described the basic structure, working principle and key technology of neural prosthetic system, summarized the application, problems and prospects of neural prosthetic technology in the rehabilitation of cervical spinal cord injury.
10.Hemodynamic Change of Anterior Tibial Artery during Acupuncture at Zusanli (ST36)
Tong ZHANG ; Weijun GONG ; Xuemei LI ; Jingfang WU
Chinese Journal of Rehabilitation Theory and Practice 2009;15(7):646-648
Objective To study physiological foundation of acupunctureDeqi.Methods 28 healthy volunteers who never experienced acupuncture were recruited. The right Zusanli (ST36) and a site 1.5 cm beside Zusanli (ST36) (nominated as A) were acupunctured at different time. Shallow and deep acupuncturing was inserted at Zusanli (ST36). Only deep acupuncturing was inserted at A. Hemodynamic parameters of the anterior tibial artery including the peak value in the systolic phase (Vmax), the average blood flow velocity (Vm), and the inner diameter of vessels (Dist) were observed with colored Doppler ultrasound before, at the end of acupuncture, and 3 min afterDeqi response. Results There was significant difference in those parameters between before acupuncture and 3 min after deqi response when deep acupuncturing at Zusanli (ST36) (P<0.05), but was not significant difference when shallow acupuncturing (P>0.05). There was significant difference in ΔVmax and ΔVm between acupuncture at Zusanli (ST36) and A points (P<0.05). Conclusion Arterial haemodynamics variation seems to be associated with acupunctureDeqi.