1.Changes of superoxide dismutase and lipid peroxide in blood serum ulcerative of colitis patient
Basic & Clinical Medicine 2001;21(2):169-171
The content of superoxide dismutase (SOD) and lipid peroxide (LPO) of blood serum in 120 ulcerative colitis (UC) patient were tested by means of xanthine oxidation method and colorimeter on the reactive product of thio-barbituric acid.The content of SOD in the UC Patients was lower than that in the normal control group (P<0.001),and the content of LPO in the UC patients was obviously higher than that the control group (P<0.001).The content of SOD in the UC patients which accompanied the types of simple retention of damp-heat in the interior or weakness of the spleen and the stomach or the stagnancy of qi and blood stasis or deficiency of yin and stagnancy of qi and blood stasis was distinctly lower tban the one in the normal control groups (P<0.001).The content of LPO in them is distinctly higher than the content of LPO in normal control group (P<0.001).Conclusion: These results suggested that the content of SOD of protecting cell factor in the body of ulcerative colitis patients who were mostly the type of retention of damp-heat in the interior decreased and the content of LPO of damaging cell factor increased.When the patients accompanied with the deficiency,the content of the SOD in them reduced remarkably and the content of LPO enhanceed remarkably,especially in those who are the type of weekness of the spleen and the stomach or insufficiency of the spleen and the stagnancy of qi and blood stasis.
2.Clinical application of 3-D surface reconstruction by multislice spiral CT in the diagnosis of impacted teeth in maxilla
Journal of Practical Stomatology 2001;0(01):-
Objective:To evaluate the feasibility of the 3-D surface reconstruction by multislice spiral CT(MSCT) technique in the diagnosis of impacted teeth in maxilla.Methods:Eighty two cases with impacted teeth in maxilla were examined with volumetric CT scan using MSCT,the dental reconstruction images were obtained with multiplanar reformation technique and 3D-reconstruction technique.Results:Dental surface 3D-reconstruction image could display the shape,location and eruption orientation of the impacted teeth clearly.Conclusion:3-D surface reconstruction by MSCT can provide valuable diagnostic and anatomic information of the impacted teeth in maxilla.
3.Pharmacological Activity of Nest of Silvestri(Macrotermes annandalei)
Weijian BEI ; Yong CHEN ; Chaoshu CHEN
Chinese Traditional and Herbal Drugs 1994;0(09):-
Experimcnts showed that the nest of Macrotermes annandalei (Silvestri ) had the activity of relieving co gh, eliminating phlegm, and bacteriostasis. It coild also promote the phagocytosis of macrophages, enhance the transformation of T-cell of lymphocyte and rasiethe ratio of ANAE cell of lymphocyte in mice.
4.Comparative study of the circumcision techniques curative effect between circumcision suture device and Shang Ring
Shenquan CHEN ; Qifei ZHANG ; Weijian ZHANG
Chinese Journal of Primary Medicine and Pharmacy 2015;(15):2318-2320
Objective To compare the clinical effectiveness among disposable circumcisionsuture device and Shang Ring in treating redundant prepuce and phimosis.Methods The clinical data of 224 cases of circumcisions done by disposable circumcision suture device(n =112)and Shang Ring(n =112)were retrospective1y analyzed. Operation time,intra -operational bleeding and postoperative complications among two techniques were compared. Results Disposable circumcision suture operation and Shang ring circumcision without significant difference in the operation time and intra -operational bleeding.There result was (6.1 ±0.8)min vs (6.5 ±1.7)min and (2.0 ±0.0)mL vs (1.8 ±0.0)mL(P >0.05).The incidence of postoperative complications with incision pain rate was 21.43% vs 50.89%,infection rate was 14.29% vs 6.25%,frenum area incision edema rate was 8.04% vs 25.89%,and the postoperative hematoma and healing time was (8.0 ±1.7)d vs (14.0 ±1.2)d,the differences were statistically significant(P <0.05).Conclusion Each of two techniques has its own advantages and disadvantages.The treatment decision making should be a detailed description to the patients,we propose that school -age children should choose Shang Ring built -in method and the others should use disposable circumcision suture device depending on the situation.
5.Association of vitamin D receptor gene TruⅠ and FokⅠ polymorphisms with lumbar degenerative disc disease in Han nationality
Weijian CHEN ; Wei YE ; Yue DING
Orthopedic Journal of China 2006;0(05):-
0.05.[Conclusion]VDR TruⅠ and FokⅠpolymorphisms are not related to LDD in Han nationality.
6.Clinical analysis on 5 cases of critically ill children complicated with pancreatic necrosis
Yimin ZHU ; Fang LIU ; Weijian CHEN
Chinese Pediatric Emergency Medicine 2011;18(2):120-122,后插一
Objective To summarize the clinical features and biological markers of critically ill children with pancreatic necrosis. Methods The clinical data of 5 ill children whose autopsy confirmed pancreatic necrosis in our hospital from 2003 to 2009 were collected and the pathological results were analyzed.Results Five cases appeared as acute onset and fever. Clinical manifestation of 2 cases included abdominal pain and 2 cases represented abdominal bulging,lots of flatulence and gastrointestinal bleeding. Four cases represented abnormal liver function and significant decrease of albumin,3 cases with increase of C-reactive protein. No case showed abnormal pancreas acoustic image of abdominal B-ultrasonography. Autopsy confirmed that 5 cases represented varying degrees necrosis of the pancreas, which complicated with the damage of adrenal gland,liver,lung,heart, spleen, kidney,intestine, thymus, mediastinal and mesenteric lymphnodes. All died in 36 hours after the children'conditions were changed. Two cases died of acute hemorrhagic necrosis of the pancreas,3 cases died of multiple organ failure based on pancreatic necrosis. Conclusion Pancreatic necrosis in critically ill children presents acute onset and short course,is prone to result in multiple organ damage or failure.
7.Implementing and understanding of clinical pharmaceutical services
Weijian LOU ; Gang HAN ; Huizhen CHEN
Chinese Journal of Hospital Administration 1996;0(12):-
Clinical pharmaceutical services include: rounds by clinical pharmacists, monitoring of dynamics and adverse effects of drugs, pharmaceutical information services and analyses on use of drugs. Considering the difficulties that clinical pharmacists have encountered in clinical pharmaceutical services like ward rounds and different clinical knowledge structures, corresponding measures have been taken to assess the work load of clinical pharmacists so as to bring into full play the role of clinical pharmacists in clinical pharmaceutical treatment and information services.
9.A retrospective analysis of 374 casualties from the Nepal earthquake
Jie ZENG ; Hua JIANG ; Weijian HU ; Kang CHEN
Chinese Journal of Emergency Medicine 2015;24(10):1086-1090
Objective To analyze the feature of victims transported from Nepal Pokhara's earthquake,and summarized the rescuing experiences got by the Chinese government medical team.Methods A total of 374 casualties from the 2015 Nepal's earthquake magnitude 8.1 transported to the Field Hospital of the Chinese government medical team were classified into four groups according to different causes of injury,and then retrospectively analyzed the types of injury,vital signs,severity of injury and causes of injury.Results Of 374 casualties,the average age was (30.1 ± 12.4) years,and were divided into group A (n =154) in which casualties trapped under ruined buildings,group B (n =123) in which the victims had crushed injury during escaping with their lives,group C (n =58) in which the wounded had injury resulted from fall on the ground during fleeing for their lives and group D (n =39) in which the injury of casualties was caused by fall from high level.Of them,273 patients (296 parts of body injured) suffered from fracture including 34 patients with severe multiple trauma.The average age in the group D (22.3 ±7.4 years old) was significant younger compared with the others (all P < 0.05).The average age in the group C (48.4 ± 13.3 years old) was significant older compared to the others (all P < 0.05).The injury probability was higher for male in the group D (14.2% vs.7.1%,x2 =5.077,P =0.024) and the injury probability was higher for female in the group C (19.7% vs 10.8%,x2 =5.635,P =0.018).The incidence of limbs fracture was highest (66.6%) in all 296 parts of body injured.The incidence of skull fracture in the group B (31.6%) was higher compared to the others (all P<0.05),and the incidence of spinal fracture in the group D (40.0%) was higher compared to the others (all P < 0.05).There was no significant difference in the severe multiple trauma incidence between the group A and the group D (16.9% vs.12.8%,x2 =0.381,P =0.537),but both group A and group D had significant higher incidence of severe multiple trauma compared to the rest two groups (all P < 0.05).The wound debridement was the leading rate of treatment among variety of treatments (57.5%) and the plaster fixation was the second high rate of treatment (30.9%),and the wound infection was found in 25 patients (17.4%) at the first dressing among 144 patients with soft tissue laceration.After active and regular debridement,72% patients' wound smear tests were negative 3 days later,and 100% were negative 7 days later.Conclusions The casualties treated by Chinese government medical team had relatively young average age,not very severe critical illness,and quite high rate of wound infection.The treatment of all kinds of fractures and open wound was a matter of critical importance.Although facing the challenge of incomplete set of medical equipment,the lacking of medicine and many other unexpected problems,the Chinese government medical team successfully fulfilled the mission with the prior experience accumulated from several domestic earthquake disaster rescue actions.
10.A case of Parkes-Weber syndrome accompanied by pseudo-Kaposi's sarcoma
Jinling TANG ; Ye SHU ; Weijian CHEN ; Yongqi LUO ; Jianping TANG
Chinese Journal of Dermatology 2014;47(11):812-814
A girl who aged eight years and seven months presented with prunosus patches on the right buttock for 8 years,gradual unilateral enlargement of the right lower limb for more than 7 years,and multiple vegetations for 1 year.Dermatological examination showed nevus flammeus and multiple malodorous vegetations over the right lower limb with high skin temperature.The right lower limb was thicker and longer than the left lower limb.X-ray examination,magnetic resonance imaging and Doppler ultrasound examination revealed high-flow vascular malformations.Pathological examination of the vegetations showed vascular proliferation,fibroblast proliferation and erythrocyte extravasation.She was diagnosed as Parkes-Weber syndrome accompanied by pseudo-Kaposi's sarcoma.