1.Understanding of the 2013 International Association of Pancreatology/American Pancreatic Association evidence-based guidelines for the management of acute pancreatitis
Chinese Journal of Digestive Surgery 2013;12(12):937-943
Acute pancreatitis is one of the most common acute abdominal disease requiring acute hospitalization worldwide.As severe acute pancreatitis associated with mortality up to 30%,rational diagnosis and management requires up-to-date evidence-based treatment guidelines.The Guidelines for the surgical management of acute pancreatitis composed by the International Association of Pancreatology (IAP) was published in 2002,since then there have been substantial improvements in the management of acute pancreatitis.The collaboration of the IAP and the American Pancreatic Association (APA) was undertaken to revise these guidelines using an evidence-based approach in 2013 and published their new guidelines 2013 IAP/APA evidence-based guidelines for the management of acute pancreatitis few months ago.This paper presented the understandings of this new guidelines and compared with related guidelines abroad.
2.Prevention of deep vein thrombosis after total knee replacement
Guofeng WU ; Xiaoliang SUN ; Weihong YAN
International Journal of Surgery 2009;36(1):27-29
Objective To investigate how to prevent deep-vein thrombosis(DVT) after total knee replace-ment(TKR).Methods Deep vein thrombosis in 87 patients after TKR from 2004 to 2007 in the Third Hospital Affiliated to Suzhou University was retrospectively analyzed.Results Amony the 87 patients,13 were found having deep vein thrombosis,5 of 38 using low-molecular-weight beparin after TKR having deep vein thrombosis,6 of 35 cases using aspirin after TKR having deep vein thrombosis,5 of the 10 eases using mechanical preventive measures having deep vein thrombosis.The difference between low-molecular-weight heparin and aspirin group was not statistically significant.Conclusion Using low-molecular-weight heparin before TKR can prevent the occurrence of deep-vein thrombosis.Using epidural anesthesia,and a low-molee-ular-weight heparin drugs or aspirin after TKR can better prevent the formation of deep-vein thrombosis.
3.Acute patella cartilage fracture: diagnosis and treatment
Guofeng WU ; Xiaoliang SUN ; Weihong YAN
International Journal of Surgery 2008;35(11):740-742
Objective To investigate the mechanism of acute patella bone cartilage fracture,and further study its diagnosis and treatment of clinical significance.Methods Collecting 21 cases of the acute patella bone cartilage fracture from July 2005 to December 2007.Eleven patients were male and ten were female,with the mean age of 31.6 (16~46) years.All the patients were treated using the arthroseopic microfracture technique after MR examination.Results All patients were followed up 6 to 18 months,did not show patellofemoral joint pain. Evaluated by Tagner rating,excellent outcomes were found in 17 cases,good in 4 cases,satisfactory results in 100% cases.Conclusion The arthroscopic microfracture technique in treatment of the patella cartilage fracture method is simple,easy to operate,can significantly improve knee function and pain,as well as the quality of life.
4.Expression of two primary target antigens (PR3 and MPO) of serum antinutrophil cytoplasmic antibodies in severe preeclampsia women
Yu SUN ; Huixia YANG ; Weihong ZHAO
Chinese Journal of Perinatal Medicine 1998;0(02):-
0. 05). No significant difference was found in maternal and neonatal complications between the ANCA( + ) and ANCA(-) subgroups in S-PE subjects. But those 4 cases who developed renal function insufficiency patients were ANCA( + ). Conclusions ANCA might be associated with renal diseases in preeclampsia women, and further studies is required to determine whether ANCA is involved with the pathogenesis of preeclampsia.
5.Pancreatoduodenectomy for the treatment of chronic local pancreatitis in the head of pancreas
Yechen LI ; Xizeng HUI ; Weihong SUN
Chinese Journal of General Surgery 2001;0(08):-
Objective To evaluate the rationale of pancreatoduodenectomy for the treatment of chronic local pancreatitis in the head of pancreas.Methods Eleven patients underwent pancreatoduodenectomy for chronic local pancreatitis in the head of pancreas with 7 cases treated by Whipple′s operation and 4 by pylorus preserving pancreatoduodenectomy.Results Postoperative stress ulcer and wound infection occurred and were cured subsequently in one each.Postoperative follow up showed good quality of life in all the 11 patients.Conclusions Pancreatoduodenectomy is an effective cure for patients suffering from chronic local pancreatitis of the head of the pancreas refractory for conservative therapy.
6.Post-operative ipsilateral occipital hematoma in a patient with mesial temporal lobe epilepsy: A case report
Lichao Sun ; Yang Lv ; Zhanpeng Zhu ; Weihong Lin ; Jiqing Qiu ; Weihong Lin
Neurology Asia 2016;21(2):177-180
We report a case of a 35-year-old right-handed male patient with drug-resistant mesial temporal lobe
epilepsy who developed ipsilateral occipital hematoma after right temporal anterior lobectomy and
amygdalohippocampectomy. Patient did not report taking any drugs with anticoagulant effect, such
as aspirin or valproate. There was no past history of hypertension and the pre-operation tests were
normal. Pre-operative brain magnetic resonance imaging revealed no abnormality in the right occipital
lobe. Overdraining of cerebrospinal fluid may have triggered this remote cerebellar hemorrhage.
7.Treatment of old thoracolumber vertebrae fracture associated with incomplete paraplegia by using anterolateral decompression and internal fixation
Xiaoliang SUN ; Weihong YAN ; Zhiwei LIU ; Yousheng SUN
Chinese Journal of Trauma 1993;0(06):-
Objective To evaluate the efficacy of anterolateral decompression and internal fixation on the treatment of old thoracolumbar vertebrae fracture with associated incomplete paraplegia. Method the clinical findings of 26 cases with old thoracolumber vertebrae fracture with associated incomplete paraplegia treated by anterolateral decompression and internal fixing were reviewed retrospectively. Results All cases were followed up for 6 months through 2.5 years. The angle of kyphosis was 23?preoperatively and 6?postoperatively. According to Frankel's grading, there were two cases at grade A, three at grade B, five at grade C, seven at grade D, nine at grade E before operation and one at grade A, three at grade B, four at grade C, six at grade D and 12 at grade E after operation. Conclusion Anterolateral decompression and internal fixation is the treatment of choice for the old thoracolumber vertebrae fracture associated with incomplete paraplegia, especially for spinal deficit generated by displacement of the middle column.
8.Neo-adjuvant chemotherapy sensitivity and associated gene expressions in cervical cancer
Jinghua LI ; Haimei SUN ; Weihong ZHAO ; Baojun YANG ; Limin FENG
Cancer Research and Clinic 2011;23(3):154-156,160
Objective To study the associations between neo-adjuvant chemotherapy (NACT)sensitivity and expression of relative proliferation and apoptosis genes in cervical cancer tissues. Furthermore,the potential roles of relative genes expression as monitor in the chemotherapy against cervical cancer tissues were studied. Methods Fifteen pathologically proved Ⅱ A stage cervical cancer patients with HPV 16 positive were divided into effective group and non-effective group according to the clinical response to NACT, the changes of HPV16-E6, p53 genes and proteins expressions were measured by real-time quantitative reverse transcription polymerase chain reaction (RT-PCR) and Western blot. At the same time, MTT assay was used to detected proliferative activity to paclitaxel liposome and carboplatin (paraplatin) in HeLa cells. Results In effective group, the overall response rate was 73.3 % (11/15) and the HPV16-E6 mRNA and protein level after NACT was significantly decreased than that before NACT (t=3.359, t=3.614, P<0.05), while p53mRNA and protein level increased significantly (t =5.852, t=2.838, P <0.05). However, there have no significant different between pre-NACT and Post-NACT of the two genes in the non-effective group. After using chemotherapy HeLa cells growth decreased. Conclusion HPV16-E6 and p53 expreesion level are useful paraneters in evaluating NACT response in cervical cancer tissues. The detection of the two genes expression is a method for predicting efficacy in NACT.
9.Cytochemical changes of effect of Sijunzitang on different types of muscle fiber after exercise
Changyi SUN ; Minghui WANG ; Daoning YANG ; Weihong WU
Journal of Jilin University(Medicine Edition) 2006;0(04):-
Objective To discuss the function of Sijunzitang on relieving the exhaustion fatigue of muscle.(Methods Thirty-two) mice were divided into Quiet group,Fatigue group,Nature recovery group and Sijunzitang group.The mice in last three groups swam in the pool for 50 min every day.During exercise 0.2 mL Sijunzitang was injected into each mouse in Sijunzitang group every day.And the same dosage of normal saline was injected into other groups.After exercise,all the mice were killed and taken as material immediately.The technique of cytochemistry and Type MPV2 microspectrophotometer were used to test quantitatively the chemical components of different types(Ⅰ type,Ⅱ_A type and Ⅱ_B type) of muscle fibers in the quadriceps of mice after exhaustion exercise.(Results After) exhaustion exercise the content of glycogen and the activity of SDH in the muscle fibers in Fatigue group reduced remarkably (P
10.An analysis of delay in publication of 293 medical postgraduates' research papers
Li LU ; Weihong ZHANG ; Xuexin SUN ; Fenghua LI ; Liming TANG
Journal of Medical Postgraduates 2003;0(12):-
Objective:To analyze the delay in the publication of medical postgraduates' research papers and provide them with a guidance for the management of academic articles.Methods:A total of 293 articles were chosen from the Journal of Medical Postgraduates published from 2005 to 2006,of which,229 were original articles and 45 were reviews,including 184 funded and 109 non-funded research papers,and their delay in publication in different periods was statistically analyzed by SPSS13.0 software.Results:The total delay in the publication of the articles was(234.7 ? 116.9) d,including(57.0?36.8) d in manuscript examination,(109.4 ? 96.4) d in editing and(61.8 ? 52.4) d in suspension.The original articles were less delayed than the reviews,(224.2 ? 7.4) d vs(272.8 ? 19.3) d,P