1.Medical wearable devices and the healthcare model innovation
Chinese Journal of Health Management 2016;(1):70-75
The design principles of healthcare wearable devices: ambient intelligence, service continuity, and micro-context provide more choice and solutions for the healthcare and social needs, and have the potential to be an integral part of the modern health care system. The use of wearable devices will contribute to the innovation of healthcare data acquisition and healthcare behaviors, the promotion of health consciousness and literacy, it also benefits the patient education, clinical pathway, medical model and health management performance.
2.Clinical analysis of COPD with bronchodilator reversibility in 47 patients
Ye WANG ; Weiguo XU ; Yong LUO
Chinese Journal of Practical Internal Medicine 2000;0(12):-
Objective To analyze the clinical features of chronic obstructive pulmanory disease(COPD)with different results of bronchodilator reversibility test.Methods A total of 47 cases of COPD were selected and given bronchodilator reversibility test and lung fuction who were divided into two groups according to the bronchodilator reversibility test.We compared these two groups with sex,age,smoke history,body mass index,levels of IgE,eosinophil and lung function.Results The positive group had a shorter history of smoking and a higher level of IgE.The amelioration of FVC,FEV1,FRC,MEF 75% and MEF 50% was higher in the positive group than the negative(P
3.Study of meal-induced hypoxemia in COPD patients and application of the modified version of the pulmonary functional status and dyspnea questionnaire (PFSDQ-M).
Huanji DONG ; Yong LUO ; Weiguo XU
Chinese Journal of Practical Internal Medicine 2001;0(05):-
Objective To study PFSDQ-M in evaluating meal-induced hypoxemia in patients with chronic obstructive pulmonary disease.Methods PFSDQ-M scores were collected from 63 COPD patients;49 of them were performed spirometry and meal-related SpO2 monitoring.On the basis of different lung function parameters,data analysis was used to assess the relationship between PFSDQ-M and meal-induced hypoxemia.Results The SpO2 fluctuation during eating period was of significant difference in COPD patients with 3 respective levels of pulmonary function parameters (P
4.Immune enhancing effect of arginine on patients with chronic obstructive pulmonary disease complicated with malnutrition.
Weiguo XU ; Yong LUO ; Ling YANG
Chinese Journal of Practical Internal Medicine 2001;0(09):-
Objective To study the immune enhancing effect of arginine on patients with chronic obstructive pulmonary disease (COPD) complicated with malnutrition.Methods Thirty cases with COPD accompanied by malnutrition received nutritional support of total calorie intake of 1 5 times of resting energy expenditure (REE).Group A(n=12) received oral administration of 30g L-arginine per day as supplementation;Group B(n=18) were control subjects.Results The nutritional parameters such as TSF(triceps skinfold) thickness,PAlb(prealbumin),CHI(creatine height index) were markedly improved in Group A than Group B,TNF-?,CD 8 decreased and IL-2,NO(nitric oxide),IgG and CD 4 increased significantly in Group A(P
5.Continuous monitor of pulse oxygen saturation in patients with chronic obstructive pulmonary disease during meal and its clinical implication
Weiguo XU ; Huanji DONG ; Yong LUO
Chinese Journal of Practical Internal Medicine 2001;0(10):-
Objective To monitor pulse oxygen saturation(SpO_2)continuously in patients with chronic obstructive pulmonary disease (COPD) so as to study its clinical implication.Methods SpO_2, thoracic and abdominal respiratory activity was continually recorded during meal time by PSG in 19 patients with COPD. Body mass index and lung function were measured respectively. Results SpO_2 was lower after meal(P
6.Clinical analysis of psychological problems in patients with rheumatic diseases
Xiaomeng LUO ; Ying LIU ; Weiguo XIAO
Chinese Journal of Rheumatology 2017;21(7):475-479
Objective To study the mental status and its influencing factors of patients with rheumatic disease. Methods Three hundreds and eighty-one patients with rheumatic diseases were assessed with the self-rating anxiety scale, self-rating depressive scale, Eysenck Personality Questionnaire symptom checklist-90, and demographic characteristics questionnaire. The comparison among groups were tested by t tests, Spearman's correlation analysis. Results Patients with anxiety symptoms accounted for 35.96%, and pre-valence rate of depression was 48.03%. The gender (r=0.87, OR=2.34) and duration (r=0.006, OR=1.006) were the risk factors and the C4 (r=-2.63, OR=0.07) was the protective factor. In patients with systemic lupus erythematosus, depression was related to education (Z=2.228, P=0.026), disease duration (Z=-2.015,P=0.044), IgG level (t=-2.266, P=0.027), T cell subsets CD8 (Z=1.981, P=0.047) and CD3 (Z=1.967, P=0.049). Anxiety was related to education (Z=2.452, P=0.014), duration (Z=-2.054, P=0.04), complement C3 (t=2.035, P=0.045), C4 (Z=-2.204, P=0.028) and IgG level (t=-2.126, P=0.036). The value of CRP(Z=-1.984, P=0.047) and IgM (t=2.243, P=0.028) of rheumatoid arthritis patients were higher in the depression group. The depression group was different in disease duration (Z=-2.631, P=0.009), gender ( χ2=4.415, P=0.042), ESR (Z=2.17, P=0.023) and CD3 cell (Z=2.023, P=0.043) in Sj?gren's syndrome patients. Correlation analysis showed positive correlation between the score of SDS, SAS and the P value (r=0.21, P=0.01) (r=0.14, P=0.007) N dimension (r=0.52, P=0.01) (r=0.55, P=0.007) of EPQ. There were negative correlation between the score of SDS, SAS and the E dimension (r=-0.23, P=0.01) (r=-0.14, P=0.006) of EPQ. Conclusion The prevalence of depres-sion and anxiety is higher in patients with depressive and anxious symptoms. They are in older age, female gender, poor education, longer duration, lower complement and lower T cell subsets when compared with those patients without depression and anxiety. Patients who have an introverted, instable, nervous temperament are more likely to be depressed and anxious. Psychological assessment intervention and therapy should be carried out as early as possible.
7.Study on the Thermic Effect of Food of Patients With Chronic Obstructive Pulmonary Disease
Yong LUO ; Ling YANG ; Weiguo XU
Journal of Chinese Physician 2001;0(08):-
Objective To study on the thermic effect of food (TEF) of patients with chronic obstructive pulmonary disease(COPD).Methods Basal energy expenditure (BEE) of 12 male cases and resting energy expenditure (REE) of 11 male cases of COPD were detected by indirect calorimetry with metabolic cart. There were no significant difference in sex, age, height and body weight between two groups' e.g:TEF=REE-BEE.Results BEE and REE were 1114?208kcal/d,1433?136kcal/d respectively, the latter was higher 28% than BEE.Conclusion TEF increases significantly which may contributes to malnutrition and non-response to nutritional support in patients with COPD.
8.Hemodynamic Assessment of Ischemic Stroke with Near-Infrared Spectroscopy
Weiguo CHEN ; Pengcheng LI ; Qingming LUO ; Shaoqun ZENG ; Bo HU
Space Medicine & Medical Engineering 2000;13(2):84-89
Objective To validate near-infrared cerebral topography (NCT) as a practical toolin tracing the regional hemodynamic changes during normal ischemic stroke model of rat. Method Middle cerebral artery occlusion (MCAO) and photosensitizer induced intracranial infarction model of rat were established. The geometric shape and infarction area were measured by NCT, functional magnetic resonance imaging (fMRI), and TTC stained anatomical imaging techniques. Result In photosensitizer induced infarction model, the correlation between anatomical infarct area and NCT image area for infarct focus were r= 0.897 for 24 h group (P<0.05) and r=0.906 for 2 months group (P<0.01),respectively. The correlation between anatomical infarction area and NCT image area for infarct focus were r=0.820 for normothermia group (P<0.05) and r= 0.851 for hypothermia group (P<0.05), respectively. The correlation between fMRI and NCT image area for infarction focus were r= 0.874 for normothermia group (P<0.05) and r= 0.782 for hypothermia group (P<0.05),respectively. Conclusion Measurement with NCT for infarction focus matched well with fMRI and anatomic sample in rats. NCT technique might be a practical tool for short-term prediction of stroke and the rehabilitation after stroke in real time.
10.Study on control information network and its real-time property
Zhuanfeng WU ; Weiguo LIU ; Guangzhao LUO ; Pusheng WU
Journal of Pharmaceutical Analysis 2008;20(1):24-32
The control network is an important developmental orientation in the remote control system. As the control network and information network are comparatively alike in the framework and technology, we can build a control network which is similar to the common information network. In the era when the information network is becoming increasingly mature, it is a royal road to construct or rebuild a control information network in the development of the control network by relying on the achievements made in the information network or current information resources. This paper expounds the construction idea of the control information network, gives the idiographic realization method and then researches into the real-time problem encountered in the control information network, and presents a three-closed-loop control system based on virtualized reality. The feasibility of the idea is validated via experiments and simulations separately.