No abstract available.
Dietary Supplements* ; Weight Loss*

No abstract available.
Humans ; Weight Loss*

No abstract available.
Stomach Neoplasms* ; Weight Loss*

Background: The weight loss benefit of semaglutide in patients with diabetes is well-documented, but its clinical utility in treating obesity among patients without diabetes is less described. We therefore assessed the efficacy and safety of subcutaneous semaglutide as treatment for obesity in patients without diabetes. Methodology: A comprehensive search of PubMed/MEDLINE, Cochrane and Google scholar was performed to identify trials on the efficacy and safety of subcutaneous semaglutide on patients with obesity without diabetes. Primary outcome was expressed as percent mean weight difference. Secondary outcomes including risk for gastrointestinal adverse events, discontinuation of treatment and serious adverse events were expressed as risk ratios. These were calculated using the random effects model. Results: The study included 4 randomized controlled trials having a total of 3,613 individuals with obesity without diabetes. The mean difference for weight reduction was -11.85%, favoring semaglutide [95% confidence interval (CI) (-12.81,-10.90), p<0.00001]. Secondary outcomes showed that the risk of developing gastrointestinal adverse events was 1.59 times more likely with semaglutide (RR 1.59, 95%CI [1.34, 1.88], p<0.00001). Risk for discontinuation due to adverse events was twice as likely in the semaglutide group (RR 2.19, 95%CI [1.36,3.55], p=0.001) and the risk for serious adverse events was 1.6 times more likely for semaglutide (RR1.60, 95%CI [1.24, 2.07], p=0.0003). Serious events were mostly of gastrointestinal and hepatobiliary disorders such as acute pancreatitis and cholelithiasis. Conclusion Among individuals with obesity without type 2 diabetes, subcutaneous semaglutide is effective for weight loss with an 11.85% reduction from baseline compared to placebo. This supports the use of semaglutide for weight management in obesity. However, risk of gastrointestinal adverse events, discontinuation of treatment and serious adverse events were higher in the semaglutide group versus placebo.
Obesity ; Weight Loss

Introduction: With the rising number of patients with diabetes, an increased trend of people having pre-diabetic state also increases. Interventions that promote weight reduction and improved physical activity decrease the risk of diabetes and even normalize blood sugar levels among pre-diabetic individuals. Promising evidence showed that the use of digital health technologies, focusing on weight loss, has significant effects on preventing diabetes. Objective: To synthesize available evidence on the effectiveness of digital health technology in achieving weight loss among pre-diabetic adults. Methods: A meta-analysis of randomized and non-randomized controlled trials among pre-diabetic adults was conducted.. A database search using The Cochrane Library, PubMed®, Google Scholar, and ProQuest was done by the investigators. Separate forest plots were developed for each outcome. Pooled estimates of mean differences for each outcome were computed. Results: Eleven trials were included. The pooled estimate demonstrated significantly higher weight loss (MD=1.77, 95%CI=0.82 to 2.73, p-value=0.0003), higher BMI reduction (MD=0.81, 95%CI=0.64 to 0.97, p-value<0.00001) and higher percent weight loss (MD=2.60, 95%CI=2.12 to 3.07, p-value<0.00001) among patients who received digital health technology interventions than controls. However, these results had high heterogeneity. Subgroup analysis by type of intervention significantly decreased the heterogeneity, with mixed interventions (combination of web pages, mobile applications, wearable technologies etc.) showing significant improvement in BMI and percent weight loss Conclusions/Recommendations The current meta-analysis demonstrated that use of digital health technology in achieving weight loss among pre-diabetic adults is more effective than usual care alone, particularly when delivered through mixed digital health technologies. Providing health education, reminders, counseling, and motivation through the web, emails, and mobile phones are recommended to achieve weight loss and BMI reduction among pre-diabetics. Further studies are recommended to evaluate the cost-effectiveness and sustainability of these interventions and whether these interventions offer long-term benefits.
Telemedicine ; Weight Loss

We report the case of a patient with hypoglycemic symptoms and weight gain. Biochemical investigations revealed endogenous hyperinsulinemic hypoglycemia. A CT scan and MRI of the abdomen were initially not successful in localizing a pancreatic mass. However, an endoscopic ultrasound was able to demonstrate a pancreatic head mass. Enucleation of the mass resulted in clinical and biochemical improvement. This report also demonstrates the pattern of weight loss after surgery, showing an initial phase of gradual weight loss followed by a rapid loss of weight. This pattern of weight loss after successful removal of an insulin-producing pancreatic neuroendocrine tumor is a novel addition to the existing knowledge we have about this condition.
Hypoglycemia ; Insulinoma ; Weight Loss

Introduction: The demanding nature of medical school causes students to experience stress, anxiety, and depressive episodes that may cause students to gain or lose weight. This study aimed to determine the association of weight changes and stress levels among a private medical school students. Methods: Data were collected two times with an interval of 30 days through on-site measurement of the students’ anthropometrics using a stadiometer and utilization of online survey questionnaires accessed via QR code. Demographics and disease states were identified in the first round of data collection while the Perceived Stress Scale-10 (PSS-10) and identification of stressors was integrated in the second round of data collection. Results: Among the 212 individuals, 69.8% were categorized into having perceived moderate stress levels, 22.2% with high stress, and 8% with low stress. Of the 212 cases, 86 gained weight, 91 lost weight, and 35 had no change in weight. Fear of failure, poor motivation, and difficulty understanding lectures are among the top overall stressors. The study noted that there is a moderate association between stress and weight changes but it is not enough to reach statistical significance (0.161), as the sample size was not reached. The study revealed that the prevailing diseases were Polycystic Ovarian Syndrome, Hypothyroidism, and Hypertension, which have varying degrees of impact on weight change. Conclusion There is an association between weight changes and stress levels among first to fourth year medical students of a private medical school from A.Y. 2023-2024.
Weight Gain ; Weight Loss ; Students, Medical

No abstract available.
Primary Health Care* ; Weight Loss*

From January 1981 to December 1981, a program of blood loss measurement was undertaken to monitor the actual loss of blood resulting from transurethral prostatic resection. An accurate measurement of blood loss was obtained by Hemoglobincyanide method, a colorimetric determination of hemoglobin in the irrigating fluid, and the measured losses were correlated with several related factors. Followings were the results: 1. Blood loss ranged from 40 to 546 ml and its mean was 170 ml. 2. Blood loss averaged 22.2 ml per gram of tissue resected, and 2.4 ml per minute of resection time. 3. A statistically significant positive interrelationship was found among operative blood loss, weight of tissue resected and resection time. 4. Hemoglobincyanide method was simple enough to be used routinely.
Transurethral Resection of Prostate ; Weight Loss

OBJECTIVES: The purpose of this study was to compare and analyse dieting practices and tendencies in 2010 and 2015 using big data. METHODS: Keywords related to diet were collected from the portal site Naver from January 1, 2010 until December 31, 2010 for 2010 data and from January 1, 2015 until December 31, 2015 for 2015 data. Collected data were analyzed by simple frequency analysis, N-gram analysis, keyword network analysis, and seasonality analysis. RESULTS: The results show that exercise had the highest frequency in simple frequency analysis in both years. However, weight reduction in 2010 and diet menu in 2015 appeared most frequently in N-gram analysis. In addition, keyword network analysis was categorized into three groups in 2010 (diet group, exercise group, and commercial weight control group) and four groups in 2015 (diet group, exercise group, commercial program for weight control group, and commercial food for weight control group). Analysis of seasonality showed that subjects' interests in diets increased steadily from February to July, although subjects were most interested in diets in July in both years. CONCLUSIONS: In this study, the number of data in 2015 steadily increased compared with 2010, and diet grouping could be further subdivided. In addition, it can be confirmed that a similar pattern appeared over a one-year cycle in 2010 and 2015. Therefore, dietary method is reflected in society, and it changes according to trends.
Diet ; Methods ; Seasons ; Weight Loss