Objective To study the incidences of falls in patients with Parkinson's disease and analyze the related factors.Methods The clinic data of 100 Parkinson's patients were retrospectively analyzed to investigate the fall incidence and the related factors.Results The fall incidence was 46.0%during hospitalization in the patients with Parkinson's disease.The single factor analysis showed that the falls incidence were higher in male patients,dizziness from drug factors,a history of falls and non-presence of their families during hospitalization than those in the non-fall group(P<0.05).Logistic regression analysis showed that male patients,dizziness from drug factors,a history of falls and non-presence of their families during hospitalization were risk factors for Parkinson's patients during hospitalization.(all P<0.05). Conclusions The high risk factors for the falls in Parkinson's patients include male patients,dizziness from drug factors,a history of falls and non-presence of their families during hospitalization.Therefore,the assessment of the risk factors for falls should be done so as to carry out fall factors control and fall risks classification management for the purpose of reducing falls.

Objective To investigate standardization of technique of retroperitoned laparoscopic ureterolithotomy.Methods Retroperitoneal laparoscopic ureterolithotomy was performed on 85 cases of ureterolithiasis(the stone size ranging from 0.8~2.5cm,40 cases in the left,45 cases in the right;and 25 had undergone unsuccessful ESWL).Results 84 cases succeeded,1 case opened becase of play D-J tube difficultly,the mean operation time was 75 minutes(48~220min),and the estimated blood loss 20~100ml,the drain tube was removed 5~12 days(mean 7 days),1 case experienced urinary leakage,1 case infective in the retroperitoneal.Conclusion Retroperitoneal laparoscopic ureterolithotomy was a safe operation,it can take the place of open surgery.

( CPR ) skills of community nurses in the regional health alliance and its influencing factors . Methods Nosocomial CPR first-aid skills of 104 in-service nurses from 6 community hospitals in the regional health alliance using a convenience sampling method were investigated .Results The score of the CPR skill examination of community nurses in the health alliance was (75.6 ±11.3), which was lower than the score of nurses in the leading hospital .The subjects with the three lowest accuracy were:the technique and the items of the bag safety inspection of the bag valve mask (8.7%, 10.6%), the CE method to hold the mask (15.4%). The multiple linear regression test showed that community nurses′education , working age , weather they had attended related training were influencing factors of the nosocomial CPR skill score of community nurses in the health alliance .Conclusions Nosocomial CPR skills of community nurses in the regional health alliance need improving .The leading hospital in the health alliance should fully integrate resources and strengthen the first -aid skill training of community nurses in the regional health alliance in order to ensure medical safety in the community.

Objective To explore the current situation of knowledge, attitude, practice (KAP) on transitional nursing of nurses in regional medical association so as to provide the base for related training and quality control in regional medical association.Methods A total of 128 nurses in regional medical association were investigated with the transitional care KAP questionnaire for nurses.Results The overall score of the transitional care KAP questionnaire for nurses was (70.11±11.46), which was at the medium level. The score of knowledge, attitude, practice was (64.51±15.88), (78.27±9.47), (63.35±18.02). The pearson correlation analysis showed that there were statistically positive correlations between knowledge and attitude, between attitude and practice, between knowledge and practice (r=0.59, 0.50, 0.55;P<0.01). It is the influencing factor of the overall score of the transitional care KAP questionnaire, knowledge, attitude, practice wether attending related training. Conclusions Nurses in regional medical association have positive attitudes on transitional nursing. However, the knowledge and practice need to be strengthened further. It is imperative to improve the training mechanism of transitional nursing of nurses in regional medical association.

OBJECTIVE To evaluate the clinical efficacy and safety of XELOX chemotherapy （oxaliplatin+capecitabine） combined with antiangiogenic agent （apatinib） and immunotherapy （camrelizumab） in patients with inoperable metastatic colorectal cancer （CRC）of microsatellite stable （MSS） type. METHODS Clinical medical records of 40 patients with inoperable metastatic CRC of MSS type treated in Lishui People’s Hospital from January 2020 to January 2021 were retrospectively collected. According to the treatment plan， the patients were divided into control group （20 cases） and observation group （20 cases）. Control group was given XELOX+apatinib regimen， while observation group was given XELOX+apatinib+camrelizumab regimen. Every 3 weeks was a treatment cycle， and the treatment lasted for 2 consecutive cycles. The objective response rate （ORR）， disease control rate （DCR）， progression-free survival （PFS）， overall survival （OS） and adverse events （AEs） were recorded for all patients. RESULTS The ORR and DCR of observation group were 65.0% and 85.0%， respectively； and the ORR and DCR of control group were 35.0% and 75.0%， respectively， with no statistical significance between 2 groups （P＞0.05）. The median PFS of observation group and control groups were 16.0 months and 8.0 months， respectively； and the median OS were 19.0 months and 12.5 months， respectively， with statistical significance between 2 groups （P＜0.05）. Each patient in both groups had at least one AEs， and the incidences of reactive skin capillary hyperplasia and hyperthyroidism in observation group （40.0%， 20.0%） were significantly higher than those in control group （both were 0） （P＜0.05）. The incidence of nausea and vomiting in control group （90%） was significantly higher than observation group （10%） （P＜0.05）. There were 14 cases （70.0%） of patients with grade 3 or above AEs in observation group， and only 5 cases （25.0%） in control group， with statistical significance between 2 groups （P＜0.05）. However， no severe AEs that could not be tolerated or fatal occurred in the two groups， which could be alleviated after drug withdrawal or treatment. CONCLUSIONS The efficacy of XELOX chemotherapy combined with apatinib and camrelizumab in inoperable metastatic CRC patients of MSS type is comparable to that of XELOX chemotherapy combined with apatinib， but it has certain advantages in ORR， PFS and OS， and controllable safety.