1.Diagnostic value of diameter ratio of pulmonary artery or ascending aorta in COPD patients with pulmonary hypertension
Chinese Journal of Primary Medicine and Pharmacy 2016;23(2):241-244,245
Objective To investigate the diagnostic value of diameter ratio of pulmonary artery or ascending aorta in chronic obstructive pulmonary disease (COPD)patients with pulmonary hypertension.Methods 60 COPD patients with secondary pulmonary hypertension were selected as the study group,then 60 cases of normal pulmonary artery pressure COPD patients were selected as the control group.By comparing the pulmonary artery and aorta diame-ter ratio rose of the two groups to judge the value slow lung disease in patients with pulmonary hypertension of the resistive prompt action.Results The MAPD and MAD ratio of the study group was significantly higher than in the control group[(1.04 ±0.01)vs (0.83 ±0.02),t =12.572,P =0.000],and pulmonary artery high pressure ratio was positively correlated with the relative coefficient of r =0.743.Conclusion MAD ratio MAPD in the diagnosis of pulmonary artery hypertension have relatively high specificity,and the risk of an exacerbation of COPD future have prompted role in helping COPD patients with pulmonary hypertension of early detection and early treatment.
2.Epidemiological study on the influence of pig-derived Ascaris to the transmission of human ascariasis
Chinese Journal of Epidemiology 2001;22(2):116-118
Objective An experimental epidemiological study was designed to investigate possible relations of pig-derived Ascaris to the transmission of human ascariasis which might be caused by cross-infection between the pig and humans. Methods In Xinjian County, Jiangxi province, two adjacent villages, Laozhi and Panzhi, with similar baseline of ascariasis in pig and human populations were selected as the study sites with a one-year longitudinal epidemiological follow-up study. People in the two villages received mass chemotherapy. Pigs received mass chemotherapy only in Panzhi village and was twice repeated with two months interval, while pigs in Laozhi village were not treated at all. In the following year after treatment on humans, ascariasis among villagers was studied cross-sectionally five times with Kato-katz technique.Results No significant difference of the re-infection patterns of human ascariasis was found between the two villages in terms of prevalence and intensity during the following year in all the five surveys (χ2<0.658,F<1.658 and P>0.1).Conclusion The results suggested that pig-derived Ascaris were mainly transmitted among pigs but had no important role on the transmission of human ascariasis. The results were in good accordance with the findings through a recent molecular genetic research on the local human-and pig-derived Ascaris worms. Possible confounding factors were discussed.
3.Diagnosis and treatment of acetabular fractures of AO Type C
Shihong XU ; Dongsheng ZHOU ; Weidong MU
Chinese Journal of Orthopaedic Trauma 2002;0(02):-
Objective To discuss the timing and methods of operative treatment of acetabular fractures of AO Type C (double- column fractures). Methods From February, 1999 to January, 2004, we treated operatively 46 cases of AO Type C acetabular fractures, including 23 cases of C- 1 type, 14 cases of C- 2 type, and 9 cases of C- 3 type. 15 cases were treated through ilioinguinal approach, 10 cases through improved Kocher- Langenbeck approach, and 21 cases through combined anterior and posterior approaches. There were 3 groups of patients according to the time from injury to operation: 15 cases got operation within 1st week after injury (Group A); 23 cases within 2nd week (Group B); 8 cases within/after 3rd week (Group C). All of them were checked with radiography and 3D CT scan before and after operation. Results 34 cases( 73.9% ) obtained anatomical reduction, 8 cases( 17.4% ) got imperfect reduction, and 4 cases( 8.7% ) had unsatisfactory reduction. All the patients were followed up for 1 year to 4 years, averaging 31 months. According to D' Aubigne and Postel Hip Score, joint function was rated as excellent in 32 cases( 69.6% ) , good in 5 cases( 10.9% ) , fair in 5 cases ( 10.9% ) and poor in 4 cases ( 8.7% ) . As far as reduction was concerned, there was a significant difference (P0.05). As far as joint function was concerned, there was a significant amelioration in Groups A and B compared with Group C (P0.05) between group A and Group B. Conclusions Good knowledge of AO classification of acetabular fractures combined with particular radiological data can result in correct diagnosis of Type C acetabular fractures. Operations should be carried out within 2 weeks after injury and efforts should be made to ensure anatomical reduction. To achieve good clinical results in treatment of Type C acetabular fractures, suitable approaches and correct reduction and internal methods are essential
4.Development of heliox-recirculating respirator based on ADuC848
Yanan CHEN ; Dan ZHOU ; Weidong WANG
Chinese Medical Equipment Journal 1989;0(03):-
From the treatment of respiratory failure, the method of breathing heliox is presented. This paper introduces the heliox-recirculating respirator based on ADuC848 which realizes PID control of heliox output through the measurements of the pressure in gas path, oxygen concentration, temperature and so on. The electronic measurement & control unit is described in detail.
5.Comparison the effect of Shengxuening tablets and ferrous succinate in treating pregnancy with anemia
Feng ZHANG ; Fuqun ZHOU ; Weidong WEI
Chinese Journal of Biochemical Pharmaceutics 2017;37(2):68-71
Objective To compare the clinical efficacy and safety of anemia during pregnancy of Shengxuening tablets and ferrous succinate treatment for clinical treatment in patients with anemia .Methods 212 cases of pregnancy in early pregnancy patients with anemia from March 2015 to February 2016 in our hospital,numbered according to the order of treatment, were randomly divided the patients into group A and group B,106 cases in each group,group A with Shengxuening tablets treatment, group B with ferrous succinate tablets treatment,two groups of patients were treated with the same program of diet guidance,all patients were treated for three months.Each patient was followed up to the end of delivery, and the two groups of patients before and after pregnancy treatment to the end of pregnancy anemia and pregnancy outcomes were compared.Comparison of two groups of patients before and after treatment for one,two and three months of hemoglobin (Hb) level,red blood cell count (RBC),serum ferritin (SF),total iron binding rate (TIBC) changes;finishing treatment of the two groups during the three follow-up of Hb, RBC, SF TIBC, which returned to normal levels at the time and, after three months of treatment and evaluate the clinical efficacy of the two groups were collected and compared during the treatment of adverse drug reactions of two groups were compared.Results After treatment for one,two and three months, levels of Hb,RBC and SF in two groups of patients were significantly higher than those before treatment,TIBC was lower than that before treatment (P<0.05);After treatment for one and two months,RBC,SF and Hb in group B were significantly higher than those in group A,TIBC lower than group A(P <0.05);After treatment for three months,the levels of Hb, RBC, SF and TIBC in two groups were back to normal,and there was no significant difference between the two groups.Hb, RBC,SF,TIBC index recovery time of group B was significantly shorter than the group A (P<0.05).After treatment for three months,there was no significant difference in clinical efficacy between two groups.The adverse drug reaction rate was significantly higher in the group B than in the group A during the treatment period (P<0.05).The end of the treatment to the end of pregnancy, five cases of group A were again the parallel treatment of anemia, 11 cases of group B were again anemia and pregnancy outcome in patients with treatment ,the adverse pregnancy rate in group A was higher than that of group B, the difference was statistically significant (P<0.05).Conclusion Shengxuening tablets and succinate iron treatment of early pregnancy anemia have advantages and disadvantages,clinical can consider the combined treatment of anemia in pregnancy,improve the clinical efficacy and safety.
6.Endoscopic diagnosis and treatment of post-cholecystectomy syndrome
Pinghong ZHOU ; Liqing YAO ; Weidong GAO
Chinese Journal of Digestive Endoscopy 1996;0(06):-
Objective To evaluate the value of endoscopy in etiological diagnosis and treatment of post - cholecystectomy syndrome. Methods Three hundred and twenty - six patients with post -cholecystectomy syndrome received ERCP. To reveral the etiology of post - cholecystectomy syndrome. For those with choledocholithiasis and those with papillary inflammatory stricture EST or EPBD were given those with papillary diverticulum and SOD EPBD were given, those with papillary tumor and hepatobiliary carcinoma EMBE were given and for those with bililary stricture in middle part of bile duct, purulent cholangitis, chloedocholithiasis(stones not excluded in one time)and bile leakage ENBD were used. Results ERCP was succeeded in 315 cases(96. 6%), 24 cases had no abnormal endoscopic findings view. 191 cases of choledocholithiasis 186 were totally get rid of stone after one to three times of opretion EST or EPBD was successfully given to 39 cases of 39 had papillary inflammatory stricture. Nine had papillary diverticulum which oppressed the papillary orifice, 7 had SOD, all of them were dealt with EPBD. Sixteen had stricture in the middle portion of bile duct, 11 of which were treated with ENBD. In 6 cases of papillary tumor and 5 hepatobiliary carcinoma patients jaundice improved significantly after received EMBE. Residual stones in cholecystic duct were seen in 4 cases. In 2 cases of bile leakage after cholecystectomy, ENBD was successfully carried out to avoid another operation. Complications were noted in 15 cases(4. 8%) of them. pancreatitis 11 cases, cholangitis 3 eases and hemorrhage of upper gastrointestinal tract one ease. Conclusion ERCP can find out the defenite cause of post - cholecystectomy syndrome at early stage and take corresponding endoscopic therapeutic measures. The complications of ERCP can be avoided by skillful operator.
7.Expression of dihydrodiol dehydrogenase 2 in prostate cancer and its significance
Weidong SONG ; Liqun ZHOU ; Lili LIANG
Chinese Journal of Urology 2001;0(09):-
Objective To study the expression of dihydrodiol dehydrogenase (DD) in prostate cancer and its significance. Methods With reference to expression of ?-actin gene,the expression level of a human dihydrodiol dehydrogenase isoform (DD2) mRNA was examined in prostate cancer tissues (11 cases) and normal prostate tissues (10 cases) by reverse transcriptive-polymerase chain reaction(RT-PCR). Quantitative determination of relevant band densities was performed using densitometry-scanning techniques. Results Strong expression of DD2 mRNA was detected in prostate cancer tissures with absorbance in the range of 0.550 to 1.018 (median,0.726),and low expression of DD2 mRNA in normal prostate tissues with absorbance in the range of 0.248 to 0.420 (median,0.333). The difference of the expression of DD2 mRNA between cancer and normal prostate was significant ( P
8.Preliminary report of anterior cervical discectomy and interbody fusion by endoscope
Yue ZHOU ; Xia ZHANG ; Weidong WANG
Chinese Journal of Orthopaedics 2000;0(02):-
Objective To explore the technical feasibility and effects of ant erior cervical discectomy and interbody fusion using endoscopic technique. Metho ds A retrospective study was undertaken in 23 patients with single segmental cer vical fracture and dislocation or cervical spondylotic myelopathy. There were 14 males and 9 females with an average age of 41.5 years (range, 23 to 64). The fr acture and dislocation patients consisted of 2 cases with complete tetraplegia e ither of C3,4 or C4,5, 3 with incomplete tetraplegia of C5,6 and 2 of C4,5 free from nervous symptoms. The operative procedures included anterior cervical disce ctomy and interbody fusion with insertion of cage or/and plate fixation through an endoscopic working canal. Results All 23 cases were followed-up from 6 to 18 months. The operative incisions healed smoothly. All patients achieved interbody fusion, and no loosening or displacement of the cage and plate occurred. For th e cervical fracture and dislocation patients, by Frankel's classification, 2 cas es with complete tetraplegia showed no any improvement, 2 cases with incomplete tetraplegia improved from grade C preoperatively to grade D postoperatively, 1 c ase with incomplete tetraplegia upgrade from C to E, 2 cases without nervous sym ptoms maintained preoperative status. For cervical spondylotic myelopathy patien ts, according to Odom's scoring system, 10 cases were assessed as excellent (dis appearance of all symptoms), 5 good (alleviation of main symptoms), 1 fair (alle viation of partial symptoms). 94% patients gained excellent and good results. No complications occurred in this series. Conclusion With the improvement of the t echnique and instrument, the endoscopic procedures can be used for anterior cerv ical discectomy, interbody fusion and internal fixation. It presents microsurgic al advantages such as minimal incision, less traumatic reaction, clear intraoper ative visualization, and less postoperative discomfort comparing to traditional approach.
9.CLINICAL TREATMENT OF LUNG CANCER BY STEREOTATIC RADIOTHERAPY COMBINED WITH EXTERNAL IRRADIATION
Guixia ZHOU ; Guoxiong CHEN ; Weidong ZHAO
Medical Journal of Chinese People's Liberation Army 1982;0(03):-
cases were histologically confirmed to be patients with squamous cell carcinoma, 4 cases to be patients with adenocarcinoma. The majority of the patients received stereotatic radiotherapy on the basis of external radiation. The single dose for stereotatic radiation was 5~10Gy, once every two days, 4~8 fractions, the total dose was 26~42 Gy by using 5~6 non-coplanar stationary beams or arc radiation. The patients′ CT was checked 2~3 months after treatment, there were 8 cases of CR( 26.7%), 18 cases of PR(60%),4 case of NR (13.3%).The median survival time was 12 months and the survival of 1 year and 2 years was 84 % and 61.2% (using Kaplan-Meier methods). The total effective rate was 86.7%. The results suggested that stereotatic radiotherapy (SRT) is effective for lung cancer at palliative and radical treatment. Combined with external irradiation, it can increase the doses of target and shorten the course of treatment.
10.Study of combined determination of XIAP and survivin for predicting the prognosis of breast carcinoma
Xing DONG ; Weidong ZHOU ; Yingying JIANG
Chinese Journal of General Surgery 1997;0(04):-
Objective To study the expressions of XIAP and survivin in breast carcinoma tissues and their(value) in predicting the recurrence of breast carcinoma.Methods The expression of XIAP and survivin in 65 benign and 65 malignant breast paraffin-embedded specimens was detected by using immunohistochemical assay and the results were compared.Results The positive rate of XIAP and survivin in recurrent breast carcinoma(recurrent group) was 82.2% and 85.7% respectively,and in non-recurrent breast carcinoma tissue(non-recurrent group) was 54.5% and 45.5% respectively,and in both groups were increased significantly as compared with that of benign breast tissues(20.0%,and 13.3% respectively).The positive expression of XIAP and survivin was increased significantly in recurrent group as compared with non-recurrent group(P