1.Effect of Occupational Therapy on Unilateral Spatial Neglect after Stroke
Chinese Journal of Rehabilitation Theory and Practice 2008;14(5):457-458
Objective To observe the effect of occupational therapy(OT) on unilateral spatial neglect(USN) in stroke patients.Methods 108 stroke patients with USN were randomly divided into OT group(54 cases) with OT and other rehabilitation therapy and control group(54 cases) without OT.They were assessed with line bisection test,number cancellation test,copying drawing test and clock-drawing before and 2 months after treatment.Results The incidence of USN of both groups were significantly reduced after treatment(P<0.01),while that of the OT group were lower than of the control group(P<0.01).Conclusion OT can significantly improve the USN after stroke.
2.Rehabilitation Training for Post-stroke Spasmodism Model Dysarthria and Its Efficacy
Chinese Journal of Rehabilitation Theory and Practice 2008;14(10):925-926
Objective To explore the method of rehabilitation training for post-stroke spasmodism model dysarthria and its efficacy.Methods 45 patients with post-stroke spasmodism model dysarthria were treated with verbal psychotherapy.Modified Frenchay dysarthric measurement was applied to assess rehabilitation efficacy.Results After rehabilitation training,the total effective rate of 45 patients was 93% after the therapy.The effective rate was 100%,96% and 85% respectively for the patients with the disease course of less than one month,between one and three months as well as more than three months.Conclusion Verbal psychotherapy is effective for post-stroke spasmodism model dysarthriaspasm,the early the training starts,the better the curative effect will be.
3.Influence of magnetic field on hemorheologic properties in rabbits
Hui LI ; Weijuan YAO ; Weibo KA
Chinese Journal of Medical Physics 2000;17(4):239-240,242,256
Rabbit blood samples were exposed to constant magnetic field within a range of intensity from 0.05 T to 0.35 T for 10 to 50 minutes, the propersities of hemorheology were measured by ektacytometry. The following results were obtained: The blood viscosity was lowed;The RBCs deformability was not changed obviously except for 10 minutes of exposure when the RBC's deformability was strongly decreased; The orientation index was increased; The results indicate that the magnetic field increases the RBC surface charge and results in the decrease of blood viscosity.
4.Effect of Occupational Therapy on Post Stroke Depression
Li YOU ; Peng ZHAO ; Li LIU ; Jiang RAO ; Weibo SHAO
Chinese Journal of Rehabilitation Theory and Practice 2013;19(8):775-777
Objective To explore the effect of occupational therapy (OT) on the depressive mood and activity of daily living (ADL) in patients with post stroke depression (PSD). Methods 42 patients with PSD were divided into OT group (n=21) and control group (n=21).Both 2 groups received routine therapy, and OT group received ADL training, selective recreation and sport and appreciation of music in addition.They were evaluated by modified Bathel index (MBI) and Hamilton Self-rating Scale for Depression (HAMD) before and after treatment.Results The scores of MBI increased and the scores of HAMD decreased significantly after 4 weeks in both 2 groups (P<0.001), especially in the OT group (P<0.01). Conclusion OT can improve not only ADL, but also the depressive mood in patients with PSD.
5.Effect of Occupational Therapy on Hemianesthesia and Hand Function after Stroke
Li YOU ; Jiang RAO ; Li LIU ; Weibo SHAO
Chinese Journal of Rehabilitation Theory and Practice 2012;18(7):638-639
Objective To explore the effect of occupational therapy (OT) on hemianesthesia and hand function after stroke. Methods 50 stroke patients with hemianesthesia were divided into OT group (n=25) and control group (n=25). The OT group accepted OT combined with routine therapy and the control group accepted routine therapy only. They were assessed with upper extremity sense of Fugl-Meyer Assessment (FMA) and evaluation of hand function before and after treatment. Results The scores of FMA and hand function improved significantly in both groups 2 months after treatment, and improved more in the OT group than in the control group (P<0.05). Conclusion OT can improve the sense and the hand function in stroke patients with hemianesthesia
6.Expression of thymidine kinase 1 in primary hepatic carcinoma and its value in prognostic prediction
Weibo BO ; Jibao QIN ; Haiying LI ; Xiaojuan FENG ; Huiyi WU
The Journal of Practical Medicine 2016;32(3):396-398,399
Objective To investigate the expressions of TK1 (thymidine kinase 1) in PHC (primary hepatic carcinoma). Methods TK1 and AFP in serum of 33 cases of PHC (primary hepatic carcinoma), 38 cases of hepatic cirrhosis,36 cases of hepatitis and 35 cases of healthy people were detected by means of Western blot—enhanced chemiluminecence and electrochemiluminescence. Results The difference of TK1 level in PHC group indicated significance when compared with that in hepatic cirrhosis group , hepatitis group and control group (U value was 436.4, 352.1, 163.6, respectively, all P < 0.01). TK1 level in patients with PHC was related with differentiation (χ2 = 7.476,P < 0.05) and TNM stage (χ2 = 7.227,P < 0.05),but not with sex, age, tumor diameter, number of tumors, vascular invasion, lymph node metastasis (P > 0.05). Kaplan-Meier curve analysis revealed that PHC patients with TK1≤ 2.0 pmol/L had a significantly shortened overall survival when compared with those with TK1 > 2.0 pmol/L (χ2 = 3.954,P < 0.05). Multivariable Cox regression analysis indicated that the level of TK1 and TNM stage were the independent risk factors for patients with PHC (all P <0.05). Conclusions The detection of TK1 has a certain clinical value in the diagnosis, monitoring and evaluation of the prognosis of the PHC.
7.Efficacy of Wearing Gloves to Protect Laboratory Staffs from Hepatitis B Virus (HBV) Infected Via Hands
Xiaodong GU ; Dan LI ; Bixia YU ; Weibo YU
Chinese Journal of Nosocomiology 2006;0(07):-
OBJECTIVE To survey hepatitis B virus(HBV) contamination on hands of laboratory staffs and to evaluate the protection efficacy against HBV infection by wearing gloves.METHODS Samples from used gloves and gloves-protected hands were carried out according to the methods stipulated in the Technical Guidelines for Disinfection.All samples were divided into 3 groups:gloves worn for 1h,gloves worn for 3h and gloves-protected hands,each group had 202 cases.To detect HBsAg and HBV DNA by microparticle enzyme immunoassay(MEIA) and fluorescence quantitative polymerase chain reaction(FQ-PCR),respectively.RESULTS HBsAg polluted rates of gloves worn for 1h,gloves worn for 3h and gloves-protected hands were 22.77%,34.65% and 2.48%,respectively;HBV DNA polluted rates of gloves worn for 1h,gloves worn for 3h and gloves-protected hands were 27.72%,41.58% and 2.48%,respectively.The HBsAg and HBV DNA polluted rates of gloves worn for 3h were higher than those of gloves worn for 1h,the difference was significant between them(P
8.Anti-inflammatory and analgesic effects in vivo and bacteriostasis effect in vitro of diuretic mixture
Wenxian GUO ; Weibo DAI ; Quanxi MEI ; Hongnian LI
Drug Evaluation Research 2017;40(2):201-205
Objective To investigate the analgesic and anti-inflammatory effects of diuretic mixture and its bacteriostasis effect in vitro,and to provide scientific basis for clinical application.Methods Ear swelling test induced by xylene,twisting reaction test induced by acetic acid,capillary permeability increase in abdominal cavity of mice induced by acetic acid,and pain test induced by formalin were used to observe the analgesic and anti-inflammatory effects of diuretic mixture at high,middle and low doses (crude drug 18.0,9.0,and 4.5 g/kg).Bacteriostatic activities of diuretic mixture were tested by K-B paper disc diffusion method.Results Diuretic mixture alleviated ear edema in mouse model at high dose (P < 0.01).Diuretic mixture at high,middle,and low dose could effectively decrease the twisting reaction (P < 0.01),inhibit capillary permeability (P < 0.05 or 0.01),and ease the ache degree of mice induced by formalin in the first phase (P < 0.01),but there was no significant difference in the degree of pain intensity of phase Ⅱ.The inhibitory rates of diuretic mixture on Staphylococcus aureus and Escherichia coli were 95.04% and 37.44%,respectively.Conclusion Diuretic mixture has significant effects on analgesia and anti-inflammation and against S.aureus and E.coli in vitro.
9.The sixth nationwide survey on radiation oncology of continent prefecture of China in 2011
Weibo YIN ; Bo CHEN ; Chunli ZHANG ; Hongzhi ZHANG ; Yexiong LI
Chinese Journal of Radiation Oncology 2011;20(6):453-457
Objective In order to evaluate the present status of Radiation Oncology in China,the Chinese Society of Radiation Oncology performed the 6th continent prefecture of China e survey.Methods Questionnaire forms were sent by mail,e-mail,telephone and FAX.Results By August 31 st,2011,there were 1162 radiation oncology centers.There was a total of 30985 employees,including 9895 doctors,1887 physicists,11689 nurses,6103 technicians and 1411 engineers.There were 1296 linear accelerators,286 telecobalt units,81 deep x-ray machine,1040 simulators,376 CT simulators,317 brachytherapy units,1427 treatment planning system,1041 dosimeters,410 X-knife,and 230 γ-knife (122 for head only,108 for head and body).There were 56847 beds for inpatients (4 centers did not report the number of beds).More than 58000 patients were treated per day ( no report from 9 centers ),and 569056 new patients were treated annually (no report from 38 centers).Conclusions Radiation oncology was developed rapidly in the last 5 years,either in personnel,equipment,and new techniques.They are still insufficient in proportion to our population.
10.A clinical study of 90 patients with pancreatic carcinoma
Deling ZOU ; Weibo LIU ; Canyang WANG ; Yuehui LI
Clinical Medicine of China 2010;26(11):1196-1197
Objective To improve the early diagnosis and prognosis factor of pancreatic carcinoma by summarizing and analyzing the clinical data. Methods The clinical data of 90 patients with pancreatic carcinoma of our hospital from 1989 to 2005 were analyzed retrospectively. Results The symptoms of pancreatic carcinoma were very complicated,the most common manifestations were bellyache,jaundice and weight loss. Main physical signs in these patients included abdominal tenderness,abdominal mass,hepatomegalia,gallbladder enlargement. Jaundice was the outstanding manifestation of pancreatic head cancer. Among all patients,16 cases accepted sugical resection(17.8%),and the 1-year,3-year,5-year survival rate were 22. 2%,11.1% and 2. 2% respectively. Our data showed that the most important prognostic factors which influenced life span were the surgical procedures,tumor size and location,histological differentiation,TNM stage. Conclusions Clinical manifestations of pancreatic carcinoma are related to TNM stage,tumor size and location,histology type,complication disease. Clinical symptoms only provide clue for diagnosis of pancreatic carcinoma. Laboratory and imaging examination will provide objective evidence for further diagnosis and prognosis in pancreatic carcinoma.