1.Leptin and osteoarthritis
International Journal of Surgery 2009;36(1):63-66
Leptin,the product of the obese gene,is a 16kDa secreted protein produced by white adipocytes.Because of its dual nature as a hormone and cytokine,leptin plays a role in regulating energy metabolism,inflam-marion,immune response,neuroendocrine and angiogenesis,and so on.The review focuses on the research and controversy of leptin's effect in osteoarthritis.
2.Analysis of Risk Factors of Recurrent Inguinal Hernia by Cox Proportional Hazard Regression Model
Chinese Journal of Bases and Clinics in General Surgery 2003;0(03):-
Objective To retrospectively analyze the risk factors of recurrent groin hernia. Methods Data came from all hernia repairs recorded in our hospital between 1991 and 2001. A total of 1 082 cases of groin hernia was analyzed through Cox proportional hazard model to determine the relative risks between recurrence and mode of admission, types of groin hernia, repair methods (traditional/tension free hernioplasty), and post operative complications.Results From 1991 to 2001,1 082 groin hernia operations were performed in our hospital, 88.9% for primary hernia and 11.2% for recurrent hernia. As compared with traditional hernia repair methods, Lichtenstein’s tension free hernioplasty technique had less relative risk for recurrent hernia repair than that for primary hernia repair. Postoperative complications and indirect hernia were linked to an increased relative risk for recurrence. Conclusion There are many factors affecting the recurrence of inguinal hernia, but the use of tension free hernia repair may decrease re recurrence of recurrent hernia.
3.Rearch and clinical application of materials to bile duct repair and reconstruction
Chinese Journal of General Surgery 1993;0(02):-
Objective To review experimental study and clinical application of materials to bile duct repair and reconstruction.Methods Comparison of different materials was made between advantages and disadvantages.Results Synthetic grafts such as vitallium,teflon are easy to handle,but have no flexion,and have foreign body reaction.Although autogenous free tissues such as venous patch and peritonium are resistant to infection,they are likley to lead to bile duct stricture because of lacking adeuqate blood supply.Vascularized neibouring tissues for repearing bile duct defect have satisfactory results.Conclusions To avoid bile duct striccture,vary measures should be taken to repair bile duct defecs;for segmental loss of bile duct,end to end anastomosis or Roux-en-Y biliary jejunal reconstruction should be applied.
4.Expression of ? opioid receptor of knee joint synovium tissue in patients with chronic knee osteoarthritis
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(09):-
Objective To evaluate the expression of ? opioid receptor of the knee joint synovium tissue in patients with chronic inflammation. Methods The patients were divided into inflammatory group and control group(n=25 for both). Those who were allocated to the inflammatory group were diagnosed as osteoarthritis by arthroscopy, and in the control group, the patients were having dislocation of patella and took internal fixation with arthroscopy. The synovium tissues were harvested from suprapateller bursa, articulation vestibule, intercondylar fossa and articulation metacele. The synovium were taken to measure ? opioid receptor by immunohistochemistry and RT-PCR in both groups. Results Immunohistochemical and RT-PCR results revealed that the expression of mRNA and the optical density (OD) of immunoreaction of ?-opioid receptor in the knee synovium tissue in the chronic inflammation group were significantly higher than those in the control group (P0.05). Conclusion The expression of ? opioid receptor of the knee joint synovium tissue in chronic inflammation was significantly up-regulated. It may play a partial role in the peripheral mechanism of morphine.
5.Progress on the associated-gene of hereditary spastic paraplegia
Wei WEI ; De WU ; Jiulai TANG
International Journal of Pediatrics 2010;37(6):622-624
There are twenty-one gene-associated sites of hereditary spastic paraplegia (HSP) that have been reported, including eleve gene-associated sites of autosomal dominant inheritance, seven gene-associated sites of autosomal recessive and three gene-associated sites of X2 linked recessive. Nine genes of HSP have been cloned as followed, atlastin, spastin, paraplegin, L1CAM, PLP, Hsp60, maspardin, TRAK1 and so on.
6.Phthalates esters and child health.
Chinese Journal of Contemporary Pediatrics 2009;11(11):949-953
Air Pollutants
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analysis
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Animals
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Child
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Esters
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toxicity
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Humans
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Liver
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drug effects
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Phthalic Acids
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analysis
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metabolism
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toxicity
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Reproduction
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drug effects
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Soil Pollutants
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analysis
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Thyroid Gland
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drug effects
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Water Pollutants, Chemical
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analysis
7.The future of spine functional reconstruction--from fusion to non-fusion.
Chinese Journal of Surgery 2006;44(16):1084-1086
Arthroplasty, Replacement
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methods
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trends
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Cervical Vertebrae
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surgery
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Diskectomy
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methods
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trends
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Forecasting
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Humans
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Lumbar Vertebrae
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surgery
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Spinal Fusion
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methods
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trends
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Spine
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surgery